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Emergency Medicine Clinics of North America, 1988
The rational selection and safe use of local anesthetic solutions is of paramount importance to the practice of emergency medicine. Such decisions are based on a sound knowledge of the pharmacology and toxicity of those agents one uses clinically in day to day practice.
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The rational selection and safe use of local anesthetic solutions is of paramount importance to the practice of emergency medicine. Such decisions are based on a sound knowledge of the pharmacology and toxicity of those agents one uses clinically in day to day practice.
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THE PHARMACOLOGY OF LOCAL ANESTHETICS
Anesthesiology Clinics of North America, 2000The pharmacology of local anesthetics is an integration of the basic physiology of excitable cells and the mechanism by which local anesthetics are capable of interrupting conduction of neural messages. The common characteristics of the molecules with local anesthetic action have been identified and can explain the properties of the agents.
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New England Journal of Medicine, 1976
Local anesthetics comprise one of the most widely used classes of drugs in medicine and dentistry, with their remarkable ability to block, quickly and reversibly, the traffic of impulses through both sensory and motor nerves. Historically, the demonstration of the general anesthetic properties of diethyl ether in 1846 antedated by 38 years Koller's ...
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Local anesthetics comprise one of the most widely used classes of drugs in medicine and dentistry, with their remarkable ability to block, quickly and reversibly, the traffic of impulses through both sensory and motor nerves. Historically, the demonstration of the general anesthetic properties of diethyl ether in 1846 antedated by 38 years Koller's ...
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Dermatologic Clinics, 1994
Although lidocaine alone will serve as an excellent anesthetic for most patients, using less painful injectable agents, topical anesthetics, and occasionally oral sedation will offer the frightened or pain-intolerant patient an acceptable and effective alternative system of local anesthesia.
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Although lidocaine alone will serve as an excellent anesthetic for most patients, using less painful injectable agents, topical anesthetics, and occasionally oral sedation will offer the frightened or pain-intolerant patient an acceptable and effective alternative system of local anesthesia.
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Narcotics and Local Anesthetics
Veterinary Clinics of North America: Equine Practice, 1993The recognition and alleviation of animal pain is a growing veterinary and public concern. Pain can be of an acute or chronic nature with different behavioral manifestations. Physiologically, pain is a dynamic and complex phenomenon that produces changes in the central and autonomic nervous systems as well as in the endocrine system.
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Best Practice & Research Clinical Anaesthesiology, 2018
Local anesthetics are used for performing various regional anesthesia techniques to provide intraoperative anesthesia and analgesia, as well as for the treatment of acute and chronic pain. Older medications such as lidocaine and bupivacaine as well as newer ones such as mepivacaine and ropivacaine are being used successfully for decades.
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Local anesthetics are used for performing various regional anesthesia techniques to provide intraoperative anesthesia and analgesia, as well as for the treatment of acute and chronic pain. Older medications such as lidocaine and bupivacaine as well as newer ones such as mepivacaine and ropivacaine are being used successfully for decades.
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Local anesthetics in dentistry
Clinical Dentistry Reviewed, 2019Since the advent of their use over a hundred years ago, local anesthetics have continued to shape the field of dentistry and its specialties by providing the means with which to accomplish a multitude of procedures in an office setting without the need for a general anesthetic. In oral and maxillofacial surgery, local anesthetics have the added benefit
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JAMA: The Journal of the American Medical Association, 1969
Patients frequently relate a history suggesting allergy to local anesthetic drugs which have been commonly recognized as causing dermatitis and systemic reactions. 1 However, there appears to be a wide discrepancy between the actual incidence and the emphasis placed on them by textbooks and lectures.
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Patients frequently relate a history suggesting allergy to local anesthetic drugs which have been commonly recognized as causing dermatitis and systemic reactions. 1 However, there appears to be a wide discrepancy between the actual incidence and the emphasis placed on them by textbooks and lectures.
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Local Anesthetics: Eutectic Mixture of Local Anesthetics
1991All commonly available local anesthetics have poor skin penetration when applied topically. One of the main reasons is that a local anesthetic agent needs to be in its cationic form in order to block nerve conduction. But it is the uncharged base which penetrates and diffuses into the tissues after topical administration.
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Archives of Dermatology, 1957
Received for publication May 21, 1957. There are a large number of agents that are used for local anesthesia by injection. Most of them I have found have one or more objections. The most commonly used ones are procaine hydrochloride, lidocaine (Xylocaine), and hexylcaine (Cyclaine). All are used in strengths of 1% to 2%.
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Received for publication May 21, 1957. There are a large number of agents that are used for local anesthesia by injection. Most of them I have found have one or more objections. The most commonly used ones are procaine hydrochloride, lidocaine (Xylocaine), and hexylcaine (Cyclaine). All are used in strengths of 1% to 2%.
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