Results 181 to 190 of about 4,350,697 (248)
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Regional Anesthesia and Pain Medicine, 2004
Skeletal muscle toxicity is a rare and uncommon side effect of local anesthetic drugs. Intramuscular injections of these agents regularly result in reversible myonecrosis. The extent of muscle damage is dose dependent and worsens with serial or continuous administration. All local anesthetic agents that have been examined are myotoxic, whereby procaine
Wolfgang, Zink, Bernhard M, Graf
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Skeletal muscle toxicity is a rare and uncommon side effect of local anesthetic drugs. Intramuscular injections of these agents regularly result in reversible myonecrosis. The extent of muscle damage is dose dependent and worsens with serial or continuous administration. All local anesthetic agents that have been examined are myotoxic, whereby procaine
Wolfgang, Zink, Bernhard M, Graf
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Local Anesthetics, Local Anesthetic Systemic Toxicity (LAST), and Liposomal Bupivacaine.
Anesthesiology ClinicsLocal anesthetics have played a vital role in the multimodal analgesia approach to patient care by decreasing the use of perioperative opioids, enhancing patient satisfaction, decreasing the incidence of postoperative nausea and vomiting, decreasing the ...
Michael O On'Gele +3 more
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The American Journal of Surgery, 1957
Abstract 1. 1. An outline of the pharmacology of propoxycaine HCI, a new local anesthetic, is presented. 2. 2. Seventy-one cases in which propoxycaine HCI was used as a local anesthetic are reviewed. 3. 3. Salient features of the satisfactory performance of propoxycaine HCI include: (a) rapid onset, (b) effective in small dosage, (c ...
J H, MITCHELL +2 more
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Abstract 1. 1. An outline of the pharmacology of propoxycaine HCI, a new local anesthetic, is presented. 2. 2. Seventy-one cases in which propoxycaine HCI was used as a local anesthetic are reviewed. 3. 3. Salient features of the satisfactory performance of propoxycaine HCI include: (a) rapid onset, (b) effective in small dosage, (c ...
J H, MITCHELL +2 more
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Emergency Medicine Clinics of North America, 1992
Emergency physicians often rely on the use of local anesthetic agents to relieve patient discomfort, and research continues in an effort to develop new agents with improved anesthetic qualities. Eventually, a nontoxic, rapidly acting agent may become available that could provide profound anesthesia of long duration when applied topically to intact skin
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Emergency physicians often rely on the use of local anesthetic agents to relieve patient discomfort, and research continues in an effort to develop new agents with improved anesthetic qualities. Eventually, a nontoxic, rapidly acting agent may become available that could provide profound anesthesia of long duration when applied topically to intact skin
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The Pharmacology of Local Anesthetics
Veterinary Clinics of North America: Equine Practice, 1991Understanding of the pharmacology of local anesthesia is important for selection of a local anesthetic for use in equine standing surgery. In general, the action potential is inhibited by local anesthetics by preventing the influx of sodium ions across the axonal membrane.
T K, Day, R T, Skarda
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Current Opinion in Anaesthesiology, 2010
Local anesthetics are not only used as drugs to block the sodium channel to provide analgesia and antiarrhythmic action. The purpose of this review is to highlight the new indications and limitations of this class of drugs.Recent research has focused on the use of intravenous local anesthetics to improve bowel function after surgery or trauma, to ...
Borgeat, A, Aguirre, J
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Local anesthetics are not only used as drugs to block the sodium channel to provide analgesia and antiarrhythmic action. The purpose of this review is to highlight the new indications and limitations of this class of drugs.Recent research has focused on the use of intravenous local anesthetics to improve bowel function after surgery or trauma, to ...
Borgeat, A, Aguirre, J
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Dental Clinics of North America, 1994
Local anesthetics have been especially important in establishing pain control as a fundamental accomplishment in clinical dentistry. When used conscientiously, local anesthetics are effective and safe. It is helpful for clinical dentists to understand the workings of these adjuncts. The more we understand them, the better we will be able to use them.
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Local anesthetics have been especially important in establishing pain control as a fundamental accomplishment in clinical dentistry. When used conscientiously, local anesthetics are effective and safe. It is helpful for clinical dentists to understand the workings of these adjuncts. The more we understand them, the better we will be able to use them.
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ABSORPTION OF LOCAL ANESTHETICS
Journal of the American Medical Association, 1958Factors that determine the rate of absorption of a local anesthetic were studied in canine and, when possible, in human subjects. The drugs used were tetracaine, cocaine, procaine, and benzocaine. Objective data was obtained in the form of actual concentrations of each drug in the blood, and the concentrations obtained by intravenous injection were ...
D, CAMPBELL, J, ADRIANI
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Facial Plastic Surgery Clinics of North America, 2020
A thorough medical history is critical in patient selection for local anesthesia facelifting. Patients with no prior issues with dental procedures and no history of significant anxiety are better candidates. Simplifying local anesthesia mixtures and using dilute concentrations will minimize dosing errors and decrease risk of local anesthesia toxicity ...
Louis M, DeJoseph, Jason D, Pou
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A thorough medical history is critical in patient selection for local anesthesia facelifting. Patients with no prior issues with dental procedures and no history of significant anxiety are better candidates. Simplifying local anesthesia mixtures and using dilute concentrations will minimize dosing errors and decrease risk of local anesthesia toxicity ...
Louis M, DeJoseph, Jason D, Pou
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A Pharmacological and Therapeutic Study of Benzyl Alcohol as a Local Anesthetic
Journal of Pharmacology and Experimental Therapeutics, 19181. Laboratory experiments with benzyl alcohol or phenmethylol show that it possesses powerful local anesthetic properties, on the one hand, and a very low toxicity as compared with other well-known local anesthetics on the other. 2. A series of clinical
D. I. Macht
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