Results 211 to 220 of about 6,300,215 (300)

Modified scalp block and total intravenous anesthesia for frontal craniotomy in a dog with a meningioma: a technical case report. [PDF]

Vet Res Commun
Freisleben P, Mangini LT, Gasparotto JC, da Silva Mielke JF, Chaves JNF, Pozzolo AAD, Takamori Sekita AM, Beckmann DV, Mazzanti A.   +8 more
europepmc   +1 more source

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

Advanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan, Lixin Tian, Lianjie Peng, Jingyu Zhang, Lining Lin, Xiaoting Zhang, Yaxian Luo, Zhichao Liu, Xinhua Yao, Mouyuan Sun, Yong He, Mengfei Yu, Huiming Wang   +12 more
wiley   +1 more source

Hyperselective Neurectomy for Upper-Limb Spasticity Under General Anesthesia or Wide-Awake Surgery: A Retrospective Comparative Cohort Study. [PDF]

JB JS Open Access
Jerome JTJ, Surendran G, Thirumagal K.
europepmc   +1 more source

AL398, A Novel NSUN6 Inhibitor, Attenuates Epithelial‐Mesenchymal Transition and Metastasis in Endometrial Cancer by Abrogating m5C‐Dependent Stabilization of Snail mRNA

Advanced Science, EarlyView.
Proposed molecular mechanism: NSUN6 catalyzes m5C methylation on Snail mRNA to enhance its stability, leading to Snail upregulation and EMT promotion. The first‐in‐class inhibitor AL398 suppresses endometrial cancer metastasis by targeting the NSUN6‐m5C‐Snail. axis. ABSTRACT Endometrial cancer (EC) constitutes a leading gynecologic malignancy for which
Xiangzhuan Zhao, Linlin Yang, Huanxiang Chen, Chenfeng Guo, Hongshen Lu, Ying Zhu, Xuanzhi Wang, Yang Li, Ruike Zhang, Zichong Huang, Yifang Chen, Keyu Jin, Zeduo Xu, Lingxiu Meng, Longfeng Zhang, Yuanyuan Han, Yicong Yan, Qiaozhen Kang, Junhu Wan, Hongyang Liu   +19 more
wiley   +1 more source

Analgesic Effectiveness of Ultrasound-Guided PECS II Block in Implantable Venous Port Catheter Placement: A Retrospective Comparative Study. [PDF]

Medicina (Kaunas)
Karatepe Ü, Bozan AA, Oterkus M, Doger C.   +3 more
europepmc   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Effects of an Ultrasound‑Guided Femoral, Sciatic, and Genitofemoral Nerve Block with Ropivacaine on EC₅ ₀ and EC₉ ₅ for High Saphenous Vein Ligation. [PDF]

Drug Des Devel Ther
Wang H, Chang J, Li Y, Chen L, Chen C, Wang Q, Gao X, Yang F, Chen S, Wang Y, Wu J, Wu G.   +11 more
europepmc   +1 more source

A Photothermally Amplified Enzyme–Nitric Oxide Co‐Regulatory System Reprograms Pathological ECM–Fibroblast Crosstalk to Alleviate Hypertrophic Scarring

Advanced Science, EarlyView.
An enzyme–nitric oxide (NO) co‐regulatory strategy reprograms pathological extracellular matrix (ECM)–fibroblast crosstalk in hypertrophic scars. Enzymatic degradation of pre‐existing ECM relieves aberrant mechanical cues, while NO‐mediated fibroblast phenotypic modulation restrains excessive collagen synthesis.
Junzhe Fu, Fan Jia, Yixian Mu, Wanzhe Liu, Dingqi Tang, Qiao Jin, Jian Ji, Youxiang Wang   +7 more
wiley   +1 more source

Enhanced Pain Management With Combined EMLA Patch and Local Anesthetic Infiltration in Transradial Angiography. [PDF]

Clin Cardiol
Nashtar MA, Azizy O, Trippe J, Canbay A, Patsalis PC, Steinmetz M.   +5 more
europepmc   +1 more source