Results 91 to 100 of about 460,880 (412)

A study to compare 0.5% hyperbaric bupivacaine with 0.5% isobaric ropivacaine intrathecally for elective lower limb surgery.

open access: yesInternational Journal of Endorsing Health Science Research, 2022
Background: Spinal anaesthesia is the most appropriate method that is more advantageous than general anaesthesia. The study was planned to comparatively assess the effects of hyperbaric 0.5% Bupivacaine with isobaric 0.5% Ropivacaine in Elective Lower ...
Muhammad Naeem Pasha   +4 more
doaj   +1 more source

Perioperative Neurocognitive Disorder: State of the Preclinical Science. [PDF]

open access: yes, 2020
The purpose of this article is to provide a succinct summary of the different experimental approaches that have been used in preclinical postoperative cognitive dysfunction research, and an overview of the knowledge that has accrued. This is not intended
Culley, Deborah J   +10 more
core  

Comparison of the qCON and qNOX indices for the assessment of unconsciousness level and noxious stimulation response during surgery [PDF]

open access: yes, 2016
The objective of this work is to compare the performances of two electroencephalogram based indices for detecting loss of consciousness and loss of response to nociceptive stimulation.
Agustí, Mercé   +8 more
core   +2 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Ketamine-Medetomidine General Anesthesia Occurs With Alternation of Cortical Electrophysiological Activity Between High and Low Complex States [PDF]

open access: yesarXiv, 2022
Anesthetic agents are known to induce a range of alterations in cortical electrophysiological activity, such as the rise of signature patterns, changes in statistical properties, and altered dynamic behavior of neural records. Plenty of methods can be used to monitor these changes, among them complexity metrics demonstrated to have the power to ...
arxiv  

Intra-Operative Discomfort in Photorefractive Keratectomy

open access: yesClinical Ophthalmology, 2021
Samuel M Philbrick,1 John L Bennion2 1Department of Operational and Readiness Medicine, Joint Base Elmendorf-Richardson Hospital, Elmendorf, AK, USA; 2Department of Ophthalmology, Saint Alphonsus Health System, Boise, ID, USACorrespondence: Samuel M ...
Philbrick SM, Bennion JL
doaj  

Local anesthetic systemic toxicity.

open access: yesAesthetic surgery journal, 2014
Local anesthetic systemic toxicity (LAST) is a rare yet devastating complication from the administration of local anesthesia. The ability to recognize and treat LAST is critical for clinicians who administer these drugs.
D. Dickerson, J. Apfelbaum
semanticscholar   +1 more source

Anatomy of Soft Tissues of the Spinal Canal [PDF]

open access: yes, 1999
Background and Objectives. Important issues regarding the spread of solutions in the epidural space and the anatomy of the site of action of spinal and epidural injections are unresolved.
Quinn, Hogan, Toth, Jeffrey M.
core   +1 more source

Safety of local anesthetics

open access: yesAnais Brasileiros de Dermatologia, 2020
Local anesthetics are essential medications for the conduction of dermatological procedures. They stop the depolarization of nerve fibers and are divided into two main categories, the amide and ester types. Systemic toxicity with reflex on the central nervous and cardiovascular systems is their most feared adverse reactions, and the anaphylactic ...
Ana Carolina Figueiredo Pereira Cherobin   +1 more
openaire   +6 more sources

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

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