Results 141 to 150 of about 304,725 (261)
Desflurane Selectively Suppresses Long-latency Cortical Neuronal Response to Flash in the Rat [PDF]
, 2009 Background—The effect of inhalational anesthetics on sensory-evoked unit activity in the cerebral cortex has been controversial. Desflurane has desirable properties for in vivo neurophysiologic studies but its effect on cortical neuronal activity and ...
Hudetz, Anthony G. +2 more
core +2 more sources
Journal of the Formosan Medical Association, 2013 Desflurane, with a low blood–gas partition coefficient, is an ideal anesthetic to achieve rapid offset and recovery from general anesthesia. Investigation of desflurane elimination from blood and respiratory gas should provide useful information with ...
Chih-Cherng Lu +6 more
doaj +1 more source
Journal of Biological Chemistry, 2013 Background: General anesthetics of diverse chemical structure potentiate GABAA receptors by binding to unknown sites. Results: A photoreactive barbiturate identifies intersubunit-binding sites distinct from, but homologous to, sites identified by ...
D. C. Chiara +7 more
semanticscholar +1 more source
Acta Scientiarum: Animal Sciences, 2008 Objetivou-se verificar a eficiência de anestésicos naturais na indução à anestesia de juvenis de pacu. Foram avaliadas quatro concentrações de mentol (50, 100, 150 e 200 mg L-1), quatro de eugenol (10, 25, 50 e 100 mg L-1) e uma de benzocaína (100 mg L-1)
André Fernando Nascimento Gonçalves +3 more
doaj
Structure-Dependent Activity of Natural GABA(A) Receptor Modulators
Molecules, 2018 GABA(A) receptors are ligand-gated ion channels consisting of five subunits from eight subfamilies, each assembled in four hydrophobic transmembrane domains.
Serhat Sezai Çiçek
doaj +1 more source
Structure and Dynamics of Brain Lobe's Functional Networks at the Onset of Anesthesia-Induced Loss of Consciousness [PDF]
arXiv, 2016 Anesthetic agents are neurotropic drugs capable of inducing significant alterations in the thalamocortical system, promoting a profound decrease in awareness and level of consciousness. There is experimental evidence that general anesthesia affects large-scale functional networks, leading to alterations in the brain's state.
arxiv
Proteomic Learning of Gamma-Aminobutyric Acid (GABA) Receptor-Mediated Anesthesia [PDF]
arXivAnesthetics are crucial in surgical procedures and therapeutic interventions, but they come with side effects and varying levels of effectiveness, calling for novel anesthetic agents that offer more precise and controllable effects. Targeting Gamma-aminobutyric acid (GABA) receptors, the primary inhibitory receptors in the central nervous system, could
arxiv
Constructing a control-ready model of EEG signal during general anesthesia in humans [PDF]
arXiv, 2019 Significant effort toward the automation of general anesthesia has been made in the past decade. One open challenge is in the development of control-ready patient models for closed-loop anesthesia delivery. Standard depth-of-anesthesia tracking does not readily capture inter-individual differences in response to anesthetics, especially those due to age,
arxiv