Results 11 to 20 of about 509,138 (315)

Pharmacokinetics, pharmacodynamics, and safety of ciprofol emulsion in Chinese subjects with normal or impaired renal function

open access: yesFrontiers in Pharmacology, 2023
Background: Ciprofol, a novel sedative–hypnotic drug, has been approved for its use in inducing and maintaining general anesthesia, as well as for providing sedation.Methods: In this phase I, single-center, parallel, controlled, open-label clinical trial,
Jun Tao   +11 more
doaj   +1 more source

Perioperative and anesthetic deaths: toxicological and medico legal aspects [PDF]

open access: yes, 2019
Background: Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology.
Argo A.   +5 more
core   +1 more source

Effect of Electroencephalography-Guided Anesthetic Administration on Postoperative Delirium Among Older Adults Undergoing Major Surgery: The ENGAGES Randomized Clinical Trial

open access: yesJournal of the American Medical Association (JAMA), 2019
Importance Intraoperative electroencephalogram (EEG) waveform suppression, often suggesting excessive general anesthesia, has been associated with postoperative delirium.
T. Wildes   +23 more
semanticscholar   +1 more source

The validity of topical drug therapy for otitis media with effusion

open access: yesМедицинский совет, 2021
Otitis media with effusion is difficult to diagnose, since the course of the disease is mostly asymptomatic, while the initial stage of the disease is very similar to Eustachiitis or the pre-perforative stage of acute otitis media.
S. V. Morozova   +2 more
doaj   +1 more source

Isoflurane induces Art2‐Rsp5‐dependent endocytosis of Bap2 in yeast

open access: yesFEBS Open Bio, 2021
Although general anesthesia is indispensable during modern surgical procedures, the mechanism by which inhalation anesthetics act on the synaptic membrane at the molecular and cellular level is largely unknown.
Fumi Kozu   +5 more
doaj   +1 more source

Continuous local anesthetic wound infusion: Impact on pain score and opioid use in patients undergoing elective mastectomy

open access: yesSaudi Journal of Anaesthesia, 2022
Introduction: Opioids are commonly used to control acute postoperative pain but their usage is associated with significant complications and the potential of addiction.
Ahmed AlFaraj   +6 more
doaj   +1 more source

Sympathomimetic anesthetics [PDF]

open access: yesCanadian Anaesthetists’ Society Journal, 1973
The characteristic anaesthetic and other pharmacological properties of phencyclidine, ketamine, dexoxadrol and etoxadrol and the structure-activity relationship of these compounds have been described. Their possible mode of action is discussed in reference to the central depressant actions of the sympathomimetic amines.
openaire   +2 more sources

Immune‐Mediated Myocarditis in Fabry Disease Cardiomyopathy

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Glycosphingolipid accumulation in Fabry cells generates a proinflammatory response that may influence disease evolution and responsiveness to enzyme replacement therapy.
Andrea Frustaci   +8 more
doaj   +1 more source

New patents on topical anesthetics. [PDF]

open access: yes, 2014
Anesthesia is defined as a total or partial loss of sensation and it may be general, local or topical, depending on the method of drug administration and area of the body affected.
CALVIERI, Stefano   +6 more
core   +1 more source

Local anesthetic systemic toxicity: current perspectives

open access: yesLocal and Regional Anesthesia, 2018
Local anesthetic systemic toxicity (LAST) is a life-threatening adverse event that may occur after the administration of local anesthetic drugs through a variety of routes.
K. El-Boghdadly, A. Pawa, K. Chin
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy