Results 341 to 350 of about 330,975 (366)
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The effect of anesthetic charge on anesthetic-phospholipid interactions
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1981Cationic and uncharged forms of a tertiary amine local anesthetic are reported to have different properties and potencies as nerve blocking agents. However, the relative capacities of each form of the local anesthetic to perturb the properties of different model membrane systems is unknown.
Philip S. Low, Stephen R. Davio
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Exaggerated Anesthetic Requirements in the Preferentially Anesthetized Brain
Anesthesiology, 1993The brain is assumed to be the site of anesthetic action, but anesthetics have effects elsewhere, such as the spinal cord. A preferentially anesthetized goat brain model was used to determine the importance of anesthetic action in the brain.Six goats were anesthetized with isoflurane; after tracheal intubation and insertion of a femoral arterial ...
Kevin Schwartz, Joseph F. Antognini
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Cancer recurrence after surgery: Direct and indirect effects of anesthetic agents *
International Journal of Cancer, 2012Surgery is of paramount importance in the management of solid tumors as definitive resection can be totally curative. Nonetheless, metastatic recurrence after surgery remains a major cause of morbidity and mortality.
A. Tavare +4 more
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Current Opinion in Anaesthesiology, 2001
Intravenous anesthetics continue to be a mainstay in the modern anesthesiologist's armamentarium. In this review the authors will discuss new advancements in the use of propofol, as well as a greater understanding as to its mechanism of action. Further, we will discuss the use of target controlled infusion systems, touch upon the possible benefits of ...
J, Petrie, P, Glass
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Intravenous anesthetics continue to be a mainstay in the modern anesthesiologist's armamentarium. In this review the authors will discuss new advancements in the use of propofol, as well as a greater understanding as to its mechanism of action. Further, we will discuss the use of target controlled infusion systems, touch upon the possible benefits of ...
J, Petrie, P, Glass
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Dermatologic Surgery, 1996
Dermatology is dependent upon the effects of local anesthetics for diagnostic and therapeutic interventions. A working knowledge of the drugs' actions and interactions is necessary for anyone aspiring to optimize the benefits derived from the use of local anesthetic agents.This article reviews nerve physiology, pharmacology, classification of local ...
R A, Skidmore +2 more
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Dermatology is dependent upon the effects of local anesthetics for diagnostic and therapeutic interventions. A working knowledge of the drugs' actions and interactions is necessary for anyone aspiring to optimize the benefits derived from the use of local anesthetic agents.This article reviews nerve physiology, pharmacology, classification of local ...
R A, Skidmore +2 more
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Regional anesthesia and pain medicine, 2012
Background and Objectives There are varying reports on the incidence of major morbidity associated with peripheral regional anesthesia. Our objective was to contribute to the knowledge regarding the incidence of local anesthetic systemic toxicity and ...
B. Sites +6 more
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Background and Objectives There are varying reports on the incidence of major morbidity associated with peripheral regional anesthesia. Our objective was to contribute to the knowledge regarding the incidence of local anesthetic systemic toxicity and ...
B. Sites +6 more
semanticscholar +1 more source
Anesthesiology Clinics of North America, 2002
The action of anesthetics on the nervous system can be understood by considering their possible interactions with neuronal function. Anesthesia may be produced by a change in the balance of inhibitory synapses (notable via GABAa receptors) and excitatory synapses (notably glutamate receptors).
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The action of anesthetics on the nervous system can be understood by considering their possible interactions with neuronal function. Anesthesia may be produced by a change in the balance of inhibitory synapses (notable via GABAa receptors) and excitatory synapses (notably glutamate receptors).
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Disposition of Anesthetic and Anesthetic-Related Agents in Ruminants
Veterinary Clinics of North America: Food Animal Practice, 1986Many factors may influence the actions and fates of anesthetic and anesthetic-related agents in ruminant animals. These considerations need to be taken into account when these drugs are employed clinically. Some of the major principles governing the disposition of CNS-active drugs are reviewed, with special emphasis on the uniqueness of ruminant ...
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Emergency Medicine Clinics of North America, 1992
Emergency physicians often rely on the use of local anesthetic agents to relieve patient discomfort, and research continues in an effort to develop new agents with improved anesthetic qualities. Eventually, a nontoxic, rapidly acting agent may become available that could provide profound anesthesia of long duration when applied topically to intact skin
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Emergency physicians often rely on the use of local anesthetic agents to relieve patient discomfort, and research continues in an effort to develop new agents with improved anesthetic qualities. Eventually, a nontoxic, rapidly acting agent may become available that could provide profound anesthesia of long duration when applied topically to intact skin
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Anesthetic technique and cancer recurrence in oncologic surgery: unraveling the puzzle
Cancer Metastasis Review, 2017R. Kim
semanticscholar +1 more source