Results 141 to 150 of about 3,086 (286)

Evaluation of midazolam-ketamine with dexmedetomidine and fentanyl for injectable anaesthesia in dogs [PDF]

dexmedetomidine and fentanyl for injectable anaesthesia in dogs. Vet.
Abhijit M. Pawde, Hari P. Aithal, Kambale M. Santosh, P. Kinjavdekar, Prakash Kinjavdekar, R. A. Ahmad, Raja A. Ahmad   +6 more
core  

Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

Advanced Science, EarlyView.
ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang, Hongyi Zhang, Haixiang Guo, Xiwen Zhang, Yidan Wang, Baoyin Wang, Tong Wang, Guokun Zhao, Qing Zhang, Fei Gao, Shuang Liang, Hao Jiang, Yu Ding, Xiliang Du, Jiabao Zhang, Yi Zheng, Xinwei Li, Bao Yuan   +17 more
wiley   +1 more source

General anesthesia and depth of anesthesia (DoA) evaluation methods in laboratory animals: a comprehensive review. [PDF]

Vet Res Commun
Altınoluk T, Kazdağlı H.
europepmc   +1 more source

Nanoparticle‐Mediated Immunometabolic‐Epigenetic Remodeling Enhances Schwann Cell‐Macrophage Interaction for Sciatic Nerve Regeneration

Advanced Science, EarlyView.
A biomimetic Prussian White nanoparticle (PW) is engineered to achieve long‐term local retention and orchestrate immunometabolic‐epigenetic remodeling for sciatic nerve regeneration. PW directly targets hexokinase 2 to suppress glycolysis, thereby elevating α‐ketoglutarate and driving Kdm4a/b‐mediated demethylation of H3K9me3.
Wenying Xu, Rongrong Wu, Zhicheng Liu, Hongyu Yan, Huan Zhang, Yuanyi Zheng, Xiaojun Cai   +6 more
wiley   +1 more source

Bridging neural circuits and clinical outcomes: a novel framework for perioperative disturbances of consciousness and cognition. [PDF]

Front Neurol
Wang X, Ma X, Shen Z, Jia Y, Wang Y, Zhang N.   +5 more
europepmc   +1 more source

EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS‐STING Pathway

Advanced Science, EarlyView.
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo, Chong Wu, Xiaobo Li, Caina Ma, Jiamin Huang, Zishuo Chen, Weiling He, Tianyu Tao, Weijing Zhang   +8 more
wiley   +1 more source

Tiletamine-Zolazepam for Total Intravenous Anesthesia in Sheep. [PDF]

J Am Assoc Lab Anim Sci
Mocarski E, Heng K, Huss M, Saenz Y, Franco B, Butts Pauly K, Jampachaisri K, Sharp P, Pacharinsak C.   +8 more
europepmc   +1 more source

The effect of tiletamine-zolazepam anesthesia to the intramedal injection of histamine in cats [PDF]

, 1992
Bettenay, Sonya V., Ihrke, Peter J., Kass, Philip H., Mueller, Ralf S.   +3 more
core   +1 more source

Reinforcing Calcium Overload via Inflammation‐Mediated Targeting to Amplify Pyroptosis and Antitumor Immunity

Advanced Science, EarlyView.
A neutrophil‐membrane‐camouflaged nanoplatform (RC@NMVs) exploits tumor inflammation to target and accumulate in tumors. Intracellular Ca2+ overload is triggered via lysosomal CaP dissolution and Ru red‐mediated Ca2+ channel blockade, synergistically inducing gasdermin‐mediated pyroptosis.
Yingying Liu, Yang Liu, Qin Fan, Jinqiao Zhang, Kexin Wen, Boyu Yuan, Xianzhou Cai, Ziliang Dong, Lianhui Wang   +8 more
wiley   +1 more source

Predictors of failed reduction after prosthetic hip dislocation. [PDF]

Eur J Orthop Surg Traumatol
Frappa N, Chernov D, Papalia AG, Fuller S, Lutnick E, Alben MG.   +5 more
europepmc   +1 more source