Results 171 to 180 of about 1,731 (219)

Perioperative dobutamine infusion in an African lion (Panthera leo). [PDF]

J Vet Med Sci
Shin D, Jeong Y, Yeon S, Lee I, Son WG.
europepmc   +1 more source

Linezolid‐mediated Prevention of Fibroblast Activation and Tissue Fibrosis via Mitochondrial Translation Inhibition

Arthritis &Rheumatology, EarlyView.
Objective Beyond its role as a ribosome‐targeting antibiotic, linezolid was recently shown to modulate immune responses by inhibiting mitochondrial translation. Because mitochondrial dysfunction is implicated in various fibrotic diseases, including systemic sclerosis (SSc), this study aimed to evaluate the antifibrotic potential of linezolid and ...
Xuezhi Hong, Yanhua Xiao, Haodong Qi, Shihao Zhu, Tim Filla, Andrea‐Hermina Györfi, Yi‐Nan Li, Meilin Xu, Langxian Zhi, Thuong Trinh‐Minh, Clara Dees, Georg Schett, Jörg H. W. Distler, Alexandru‐Emil Matei   +13 more
wiley   +1 more source

Ketamine in Diabetes Care: Metabolic Insights and Clinical Applications. [PDF]

Pharmaceutics
Sukhram SD, Sanchez M, Anidugbe A, Kupa B, Edwards VP, Zia M, Yilmaz G.   +6 more
europepmc   +1 more source

A multifaceted interplay between hemophagocytosis, IL‐18 and type I IFN distinguishes Still disease from other autoinflammatory diseases

Arthritis &Rheumatology, Accepted Article.
Objectives The unknown pathophysiology and the lack of specific features for systemic Juvenile Idiopathic arthritis and adult‐onset Still disease (collectively Still disease/SD) delays diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory diseases ...
Yvonne M. Mueller, Charlotte Girard, Harmen J. G. van de Werken, Stefan J. Erkeland, Dwin G.B. Grashof, Laurie Vaillant, Renske J.H. den Dekker, Iris van Zuijen, Sharon Veenbergen, Fanny Coffin, Eric Bindels, Yvan Jamilloux, Katerina Laskari, ImmunAID consortium, Vassili Soumelis, Bruno Fautrel, Cem Gabay, Peter D. Katsikis   +17 more
wiley   +1 more source

Synaptic fidelity for drug development: is it time to move beyond glutamate release and receptors? [PDF]

Expert Opin Ther Targets
Abdallah CG, Tamman AJF.
europepmc   +1 more source

Calcium retinoate nanoparticle mediated microglial polarization to regulate inflammatory microenvironment for therapy of neuroinflammatory disease

BMEMat, EarlyView.
A nano‐drug based on retinoic acid and calcium is developed, which can be rapily endocytosed by microglia and decomposed into small molecule/ion storms in lysosomes. This nano‐drug regulates microglial phenotype switching from M1 to M2 while indirectly guiding neuronal differentiation of endogenous neural stem cells, thereby ameliorating ...
Shuo Zhang, Yuan Yao, Wenfeng Shao, Jiapei Shi, Benjie Wei, Chunhui Sun, Jingang Wang, Jiaming Shi, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Na Ren, Yuchun Tang, Wenjuan Zhou, Shuping Wang   +13 more
wiley   +1 more source

General Anesthetics: Aspects of Chirality, Pharmacodynamics, and Pharmacokinetics. [PDF]

Pharmaceuticals (Basel)
Čižmáriková R, Habala L, Valentová J.   +2 more
europepmc   +1 more source

Evaluation of Depth of Anesthesia Sleep Quality in Swine Undergoing Hernia Repair: Effects of Romifidine/Ketamine-Diazepam Protocols with and Without Tramadol and the Potential Role of Serotonin as a Biomarker. [PDF]

Vet Sci
Bruno F, Leonardi F, Spadola F, Bruschetta G, Licata P, Neve VC, Costa GL.   +6 more
europepmc   +1 more source

Seizure following in-office lidocaine administration: a case report on local anesthetic systemic toxicity. [PDF]

Ther Adv Drug Saf
Chan D, Wood C, Rafizadeh A, Nagai M.
europepmc   +1 more source

The central clinical relevance of near-death experiences in acute care contexts: identification, prediction, and management. [PDF]

Front Psychol
Michael P, Fritz P, Gosseries O, Rousseau AF, Ancion A, Ghuysen A, Martial C.   +6 more
europepmc   +1 more source