Results 11 to 20 of about 3,086 (286)
Advantages of ketamine in pediatric anesthesia
Open Medicine, 2022 Although ketamine is primarily used for induction and maintenance of general anesthesia, it also presents sedative, amnestic, anesthetics, analgesic, antihyperalgesia, neuroprotective, anti-inflammatory, immunomodulant, and antidepressant effects.
Simonini Alessandro +3 more
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Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation. [PDF]
, 2014 BackgroundMany anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABAA) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar
Brosnan, Robert J, Pham, Trung L
core +2 more sources
Sex and Gender Differences in the Effects of Novel Psychoactive Substances
Brain Sciences, 2020 Sex and gender deeply affect the subjective effects and pharmaco-toxicological responses to drugs. Men are more likely than women to use almost all types of illicit drugs and to present to emergency departments for serious or fatal intoxications. However,
Liana Fattore +3 more
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Synthesis and characterization of phencyclidine and his derivatives [PDF]
Hemijska Industrija, 2010 Phencyclidine (PCP) or 1-phenyl-cyclohexylpiperidine is the best known representative drug from the compound class of arylcyclohexylamines. On an account of pharmacological activities it belongs to the family of drugs known as a dissociative anesthetics.
Ilić Nataša C. +3 more
doaj +1 more source
Frontiers in Veterinary Science, 2022 BackgroundLocal and regional anesthetic procedures are valuable tools in veterinary practice. Caudal epidural administration of local anesthetic agents is widely reported for surgical interventions of the tail, anus, rectum, vulva, vagina, urethra, and ...
Mohamed Marzok +7 more
doaj +1 more source
PHARMACOLOGIC EFFECTS OF CI-581, A NEW DISSOCIATIVE ANESTHETIC, IN MAN [PDF]
Survey of Anesthesiology, 1965 Pharmacologic actions of CI‐581, a chemical derivative of phencyclidine, were determined in 20 volunteers from a prison population. The results indicate that this drug is an effective analgesic and anesthetic agent in doses of 1.0 to 2.0 mg. per kilogram.
Domino, Edward F. +2 more
openaire +3 more sources
Frontiers in Physiology, 2019 1. A comparative descriptive analysis of systemic (sodium pentobarbital, sodium thiopentone, ketamine) and volatile (halothane, isoflurane, enflurane) general anesthetics revealed important differences in the neuronal responses of identified motor ...
Hadi Fathi Moghadam +6 more
doaj +1 more source
Dissociative paraplegia after epidural anesthesia: A case report [PDF]
, 2013 10.1186/1752-1947-7-56Journal of Medical Case ...
Hirjak, D. +4 more
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Neuronal entropy depends on the level of alertness in the parkinsonian globus pallidus in vivo [PDF]
, 2014 A new working hypothesis of Parkinson's disease (PD) proposes to focus on the central role of entropy increase in the basal ganglia (BG) in movement disorders. The conditions necessary for entropy increase in vivo are, however, still not fully described.
Andres, Daniela Sabrina +3 more
core +3 more sources
The role of setting for ketamine abuse: clinical and preclinical evidence [PDF]
, 2012 Drug abuse is often seen as a unitary phenomenon, partly as a result of the discovery over the past three decades of shared mechanisms of action for addictive substances. Yet the pattern of drug taking is often very different from drug to drug.
Sprenger +8 more
core +1 more source