Results 51 to 60 of about 3,086 (286)

The Discriminative Stimulus Properties of Hallucinogenic and Dissociative Anesthetic Drugs

open access: yes, 2016
The subjective effects of drugs are related to the kinds of feelings they produce, such as euphoria or dysphoria. One of the methods that can be used to study these effects is the drug discrimination procedure. Many researchers have been trying to elucidate the mechanisms that underlie the discriminative stimulus properties of abused drugs (e.g ...
Tomohisa, Mori, Tsutomu, Suzuki
openaire   +2 more sources

Anesthetic protocol using propofol and isoflurane in spectacled bear (Tremarctos ornatus) [PDF]

open access: yes, 2023
The management of wild animals generally requires chemical containment with the use of sedatives, tranquilizers, general anesthetics or dissociative drugs.
Farias, Roberto Citelli   +6 more
core   +2 more sources

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

open access: yesAdvanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim   +6 more
wiley   +1 more source

Combined effects of dissociable and undissociable local anesthetics upon ATP-induced firefly bioluminescence. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1976
Combined effects of two drugs present simultaneously are usually expressed as summation, synergism or potentiation, and antagonism. When the sum of the effects of each drug present separately equals the combined effect of the two drugs present simultaneously, the action is called additive or summation.
H, Kamaya, I, Ueda, H, Eyring
openaire   +2 more sources

Brain perfusion, part 2: anesthesia and brain perfusion in small animals [PDF]

open access: yes, 2010
Sedatives and anesthetics can influence cerebral metabolism and respiratory and cardiovascular dynamics, which results in changes in cerebral perfusion.
Gielen, Ingrid   +4 more
core   +1 more source

The incidence of unpleasant dreams after sub-anaesthetic ketamine [PDF]

open access: yes, 2009
Ketamine is an N-methyl-D-aspartate (NMDA)receptor antagonist with psychotogenic effects and for whichthere are diverse reports of whether pleasant or unpleasantdreams result during anaesthesia, post-operatively or aftersub-anaesthetic use.
A Ellingson   +92 more
core   +1 more source

Tissue Engineered Human Elastic Cartilage From Primary Auricular Chondrocytes for Ear Reconstruction

open access: yesAdvanced Functional Materials, EarlyView.
Despite over three decades of research, no tissue‐engineered solution for auricular reconstruction in microtia patients has reached clinical translation. The key challenge lies in generating functional elastic cartilage ex vivo. Here, we integrate synergistic cell‐biomaterial strategies to engineer auricular grafts with mechanical and histological ...
Philipp Fisch   +13 more
wiley   +1 more source

Descripción anestesiológica del efecto de un protocolo en base a Azaperona y Ketamina en conejo doméstico (oryctolagus cuniculus) [PDF]

open access: yes, 2007
The effects of the anaesthetic protocol, based on a premedication with atropine and azaperone (Stresnil ®) and the anesthetic induction with a 0.5% ketamine solution, were studied in 25 healthy adults rabbits.Each animal was premed with 0.04 mg/kg b.w ...
Bastías, Andrés   +4 more
core   +2 more sources

Artifact‐Minimizing Ultrathin Transparent Electrodes Fabricated via iCVD for In Vivo Optogenetic Stimulation and Neural Signal Monitoring of Primary Visual Cortex

open access: yesAdvanced Functional Materials, EarlyView.
We present ultrathin flexible transparent electrodes through iCVD‐enabled molecular control of 10 nm gold films on poly(dimethylaminomethylstyrene). In vivo validation demonstrated photoelectric artifact reduction vs. opaque electrodes and preservation of natural neural dynamics.
Tae Jin Mun   +11 more
wiley   +1 more source

Self‐Assembled Nanoclay Gel With Spheroid MSC‐Derived Exosome Mimetics to Integrate Demineralized Bone Matrix and Noggin‐Targeting miRNA for Synergistic Osteogenesis

open access: yesAdvanced Functional Materials, EarlyView.
We report a versatile nanoclay gel carrier platform that enhances the osteogenic efficacy of demineralized bone matrix (DBM) by integrating nanoclay‐based self‐assembly with cell‐derived exosome mimetics loaded with noggin‐targeting miR‐200c. This design amplifies BMP signaling, thereby promoting DBM‐mediated osteogenesis and offering a promising ...
Changlu Xu   +7 more
wiley   +1 more source

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