Results 91 to 100 of about 952,770 (304)
Arthritis Care &Research, EarlyView.Objective The aim of this study was to apply sequence analysis (SA) to phenotype health care patterns of adult patients with musculoskeletal (MSK) conditions using primary care electronic health records and to investigate the association between these health care patterns and patients’ self‐reported outcomes after consultation.
Smitha Mathew +6 more
wiley +1 more source
Chloride of Ethyl as a General Anesthetic [PDF]
The Boston Medical and Surgical Journal, 1903 n ...
openaire +3 more sources
Electrostatic Contributions of Aromatic Residues in the Local Anesthetic Receptor of Voltage-Gated Sodium Channels [PDF]
, 2008 Antiarrhythmics, anticonvulsants, and local anesthetics target voltage-gated sodium channels, decreasing excitability of nerve and muscle cells. Channel inhibition by members of this family of cationic, hydrophobic drugs relies on the presence of highly ...
Ahern, Christopher A. +3 more
core +2 more sources
Arthritis Care &Research, EarlyView.Objective Walk With Ease (WWE) is a six‐week arthritis‐appropriate evidence‐based physical activity program traditionally offered in a face‐to‐face format. Because many populations encounter participation barriers to in‐person programs, WWE was modified for telephone delivery (WWE‐T).
Christine A. Pellegrini +5 more
wiley +1 more source
Intravenous anesthetics have differential effects on human potassium channels
Acta Biochimica et Biophysica SinicaGeneral anesthetics are widely used in the clinic and greatly promote the development of surgery. However, the incidence of cardiovascular and respiratory complications caused by general anesthetics is still high, and the underlying mechanisms remain ...
Tao Ying +9 more
doaj +1 more source
Using the adjuvants during infusion of local anaestetics into caudal-epidural space in newborns
Patologìâ, 2012 Markers of stress and central haemodynamics were investigated in 45 newborns. General anesthesia and caudal infusion of local anesthetics were combined in 15 newborns. Promedol and clonidine were added to local anesthetics in 15 newborns.
M. Yu. Kurochkin
doaj +1 more source
The Effects of General Anesthetics on Synaptic Transmission
Current Neuropharmacology, 2020 General anesthetics are a class of drugs that target the central nervous system and are widely used for various medical procedures. General anesthetics produce many behavioral changes required for clinical intervention, including amnesia, hypnosis, analgesia, and immobility; while they may also induce side effects like respiration and cardiovascular ...
Hui Yang +9 more
openaire +4 more sources
Arthritis Care &Research, EarlyView.Objective Pediatric rheumatologic diseases (PRDs) are characterized by high rates of anxiety and depression known to impact health‐related outcomes. We present guidance statements to assess and manage mental health concerns for youth with PRDs in pediatric rheumatology practice.
Natoshia R. Cunningham +21 more
wiley +1 more source
Mechanism of Anesthetic Action: Oxygen Pathway Perturbation Hypothesis [PDF]
Medical Hypothese (2001) 57(5): 619-627., 2001 Although more than 150 years have past since the discovery of general anesthetics, how they precisely work remains a mystery. We propose a novel unitary mechanism of general anesthesia verifiable by experiments. In the proposed mechanism, general anesthetics perturb oxygen pathways in both membranes and oxygen-utilizing proteins such that the ...
arxiv
A high-throughput approach for identification of novel general anesthetics. [PDF]
PLoS ONE, 2009 Anesthetic development has been a largely empirical process. Recently, we described a GABAergic mimetic model system for anesthetic binding, based on apoferritin and an environment-sensitive fluorescent probe.
Wendy A Lea +6 more
doaj +1 more source