Results 91 to 100 of about 6,404,771 (353)

Intravenous anesthetics have differential effects on human potassium channels

Acta Biochimica et Biophysica Sinica
General anesthetics are widely used in the clinic and greatly promote the development of surgery. However, the incidence of cardiovascular and respiratory complications caused by general anesthetics is still high, and the underlying mechanisms remain ...
Tao Ying, Yao Kejie, Wu Jing, Xu Tian, Lin Junhui, Qin Yi, Su Diansan, Cai Shiqing, Yu Weifeng, Chen Xuemei   +9 more
doaj   +1 more source

ANESTHETIC, ANALGETIC, HYPNOTIC – ARE THE TERMS IMPORTANT?

Вестник анестезиологии и реаниматологии, 2017
The review is devoted to pharmacology of the general anesthesia in the light of current understanding of this event and as a medical technique. The discussion covers the classification of medications used for general anesthesia basing on action mechanisms
A. E. Karelov, K. M. Lebedinskiy, V. I. Buravtsov   +2 more
doaj   +1 more source

Where, how, and how much? A multicenter cohort study of the relationship between lupus decision aid modality, place of administration, interruption and viewing completeness and patient‐reported outcomes

Arthritis Care &Research, Accepted Article.
Objective We assessed whether shared decision‐making (SDM), and patient acceptability, feasibility, and overall satisfaction with a computerized patient decision aid (PtDA) for patients with systemic lupus erythematosus (SLE), differs by PtDA setting, modality, and the viewing experience.
Jasvinder A. Singh, Mark Beasley, Larry R. Hearld, for the Implementing DEcision‐Aid for Lupus in clinics (IDEAL) Consortium   +3 more
wiley   +1 more source

Shaker-Related Potassium Channels in the Central Medial Nucleus of the Thalamus Are Important Molecular Targets for Arousal Suppression by Volatile General Anesthetics

Journal of Neuroscience, 2013
The molecular targets and neural circuits that underlie general anesthesia are not fully elucidated. Here, we directly demonstrate that Kv1-family (Shaker-related) delayed rectifier K+ channels in the central medial thalamic nucleus (CMT) are important ...
M. Lioudyno, Alexandra M Birch, Brian S. Tanaka, Y. Sokolov, A. L. Goldin, K. Chandy, James E. Hall, M. Alkire   +7 more
semanticscholar   +1 more source

Spin-Mediated Consciousness Theory: An Approach Based On Pan-Protopsychism [PDF]

, 2002
As an alternative to our original dualistic approach, we present here our spin-mediated consciousness theory based on pan-protopsychism. We postulate that consciousness is intrinsically connected to quantum mechanical spin since said spin is embedded in ...
Hu, Huping, Wu, Maoxin
core  

Lipid Ion Channels

, 2010
The interpretation electrical phenomena in biomembranes is usually based on the assumption that the experimentally found discrete ion conduction events are due to a particular class of proteins called ion channels while the lipid membrane is considered ...
Heimburg, Thomas
core   +1 more source

Treating lupus nephritis patients to lupus low disease activity reduces renal relapse and preserves long‐term kidney function

Arthritis Care &Research, Accepted Article.
Objective Lupus low disease activity state (LLDAS) is a validated treatment target in systemic lupus erythematosus (SLE) but limited studies have explored the role of LLDAS in lupus nephritis (LN). This study aims to investigate the frequency and predictors of LLDAS attainment, and its benefit on LN relapse and renal function preservation in patients ...
Chak Kwan Cheung, Desmond YH Yap, KL Lee, Philip H Li, Iris YK Tang, Chak Sing Lau, Shirley CW Chan   +6 more
wiley   +1 more source

Development of a personalized visualization and analysis tool to improve clinical care in complex multisystem diseases with application to scleroderma

Arthritis Care &Research, Accepted Article.
Background In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of a scleroderma patient's ...
Ji Soo Kim, John Scott, Lauren Fisher, Lauren N. Smith, Willie Stewart, Adrianne Woods, Rob Smithwright, Diane Koher, Parastoo Aslanbeik, Aalok B. Shah, Brad Tibbils, Samantha I. Pitts, Ayse P. Gurses, Yushi Yang, Ana‐Maria Orbai, Antony Rosen, Laura K. Hummers, Scott L. Zeger, Ami A. Shah   +18 more
wiley   +1 more source

Research progress on mitochondrial mechanisms of sensitivity to inhalational anesthetics

Zhongguo linchuang yanjiu
Experimental animals and people have different sensitivity to inhalational anesthetics, which is related to the depth of anesthesia during general anesthesia and the perioperative safety of patients.
CHENG Sijing*, WEI Yiyong, WANG Haiying
doaj   +1 more source

The influence of anesthetics, neurotransmitters and antibiotics on the relaxation processes in lipid membranes [PDF]

, 2007
In the proximity of melting transitions of artificial and biological membranes fluctuations in enthalpy, area, volume and concentration are enhanced. This results in domain formation, changes of the elastic constants, changes in permeability and slowing ...
Antonov V. F., Antonov V. F., Blume A., Bovill J. G., Brown D. A., Böckmann R. A., Böttner M., Cannon B., Cantor R. S., Cantor R. S., Cantor R. S., Chapman D., Cruzeiro-Hansson L., Ebel H., Ebel H., Elamrani K., Franks N., Gaus K., Gennis R. B., Genz A., Grabitz P., Gruenewald B., Halstenberg S., Halstenberg S., Heimburg T., Heimburg T., Heimburg T., Heimburg T., Heimburg T., Helms J. B., Hill T. L., Hinderliter A., Hinz H.-J., Holzwarth J. F., Holzwarth J. F., Jackson M. B., Jacobson K., Johnson M. L., Kaufmann K., Kharakoz D. P., Korlach J., Krasowski M., Lee J., Melchior D. L., Melo E. C., Mitaku S., Mountcastle D., Nagle J. F., Onsager L., Onsager L., Papahadjopoulos D., Pollakowski D., Sackmann E., Salinas D. G., Schmidt D., Seeger H., Seeger H. M., Seeger H. M., Simons K., Singer S., Steim J. M., Strehlow U., Tamura K., Thompson T., Trudell J. R., Träuble H., Tsong T. Y., Tsong T. Y., Turnheim K., Ueda I., van Osdol W. W., van Osdol W. W., van Osdol W. W., van Osdol W. W., Vaz W. L., Winter R., Yao H.   +76 more
core   +2 more sources