Results 141 to 150 of about 6,244,144 (279)

Diverse Treatment Goals in Psoriatic Arthritis: Insights from participants in the PARC cohort

Arthritis Care &Research, Accepted Article.
Objective The aim was to examine patient‐reported treatment goals among individuals with psoriatic arthritis (PsA). Methods Participants in the Psoriatic Arthritis Research Consortium (PARC) completed standardized assessments including patient‐reported outcome (PROs) instruments between 2017‐2020.
Astia Allenzara, Kat Bush, M. Elaine Husni, Soumya M. Reddy, Jose U. Scher, Ethan Craig, Joelle Koplin, Jessica A. Walsh, Alexis Ogdie   +8 more
wiley   +1 more source

Antagonism of propofol anesthesia by alkyl-fluorobenzene derivatives

Scientific Reports
Despite their frequent use across many clinical settings, general anesthetics are medications with lethal side effects and no reversal agents. A fluorinated analogue of propofol has previously been shown to antagonize propofol anesthesia in tadpoles and ...
Diana M. Plasencia, Liam H. Rodgers, Alexys R. Knighton, Roderic G. Eckenhoff, E. Railey White   +4 more
doaj   +1 more source

Preventive Effect of Metformin in Radiation‐Induced Xerostomia

Advanced Biology, EarlyView.
Head and neck cancer patients who received radiotherapy complain of severe dry mouth due to damage to the salivary glands. Metformin is an antidiabetic drug, but its radio‐protective effect has been reported. It is confirmed that metformin protects the salivary glands from radiation and provides evidence for the use of metformin in cancer treatment in ...
Sungryeal Kim, Jeong‐Mi Kim, Eun‐Jeong Jeon, Seo‐Young Park, Jin‐Mi Park, Jeong‐Seok Choi   +5 more
wiley   +1 more source

Local anesthetic infiltration vs. nervous blocks in face’s skin lesions: what’s new [PDF]

, 2018
Skin tumors are the most common type of cancer. They are localized throughout the body, more frequently in those regions chronically exposed to sun, like face, scalp and neck, compromising aesthetic appearance.
Arrico, L., Brancadoro, D., Collini, S., Grippaudo, F., Troisi, F.   +4 more
core  

Mechanical Metamaterials for Bioengineering: In Vitro, Wearable, and Implantable Applications

Advanced Engineering Materials, EarlyView.
Mechanical metamaterials with engineered architectures exhibit properties that differ from and greatly surpass those of their constituent bulk materials. This review summarizes the applications of mechanical metamaterials in bioengineering, focusing on advances in the last 5 years.
Madihah Kazim, Aniket Pal, Debkalpa Goswami   +2 more
wiley   +1 more source

Characterization of Large Scale Functional Brain Networks During Ketamine-Medetomidine Anesthetic Induction

, 2016
Several experiments evidence that specialized brain regions functionally interact and reveal that the brain processes and integrates information in a specific and structured manner. Networks can be used to model brain functional activities constituting a
Padovani, Eduardo C.
core  

SCS: Superior‐Vena‐Cava Compressing Shape‐Memory‐Alloy‐Based Implantable Device for Heart Failure

Advanced Engineering Materials, EarlyView.
An implantable superior–vena‐cava compression device, utilizing biocompatible shape‐memory‐alloy actuators, regulates blood flow and thereby achieves an 18.6% reduction in end‐diastolic left ventricular volume in a porcine model of ADHF. This potential long‐term solution minimizes thrombosis risk by avoiding direct blood contact, offering a significant
Yongjin Kim, Jeonghyeon Lee, Jeongwon Kim, Domin Cho, Hyunwoo Lee, Se Jin Oh, Amy Kyungwon Han   +6 more
wiley   +1 more source

A Novel Protein‐Polysaccharide Oral Nanoemulsion Targeting Activated Hepatic Stellate Cells to Enhance the Therapeutic Effect of Pirfenidone on Fibrosis After Transarterial Chemoembolization for Liver Cancer

Advanced Functional Materials, EarlyView.
Transarterial Chemoembolization (TACE) may aggravate liver fibrosis. In this study, a novel oral targeting nanoemulsion is fabricated to enhance the therapeutic effect of antifibrotic drug‐pirfenidone (PFD) on fibrosis after TACE. Studies have shown that PFD nanoemulsion can enhance the oral liver targeting effect of PFD, and effectively improve the ...
Zhimei Cheng, Shan Xu, Yi Lei, Huizhou He, Runbin Sun, Xingle Jin, Cheneryu Huang, Yuhao Zheng, Jianqing Peng, Lei Tang, Peng Luo, Yi Chen, Shuai Zhang   +12 more
wiley   +1 more source

Magnetic Field‐Assisted Conductive Nerve Guidance Conduit Enabling Peripheral Nerve Regeneration with Wireless Electrical Stimulation

Advanced Functional Materials, EarlyView.
This study introduces a conductive nerve guidance conduit integrated with wireless electrical stimulation through alternating magnetic fields, which induces currents and creates a supportive microenvironment for nerve regeneration. In vivo studies show that this approach significantly enhanced myelin restoration, gastrocnemius muscle regeneration ...
Shiheng Liu, Li‐Fang Zhu, Ming‐Wei Chang, Chao Li, Tingyu Wang, Rong Wang, Xinghao Yan, Baolin Wang   +7 more
wiley   +1 more source

Conducting Polymer Microelectrode Arrays for Simultaneous Electrophysiology and Advanced Brain Imaging

Advanced Functional Materials, EarlyView.
A flexible micro‐electrocorticography array with PEDOT:SS electrodes is shown to be compatible with ultra‐high magnetic field MRI up to 9.4 T. Multimodal brain monitoring is demonstrated by performing simultaneous blood oxygen level‐dependent functional MRI in parallel with electrophysiology.
Sagnik Middya, Alejandro Carnicer‐Lombarte, Stephen Sawiak, Sam Hilton, Vincenzo F Curto, Damiano G Barone, Gabriele S Kaminski Schierle, George G Malliaras   +7 more
wiley   +1 more source