Results 11 to 20 of about 6,408,160 (262)
The impact of preoperative glycated hemoglobin (HbA1c) on postoperative complications after elective major abdominal surgery: a meta-analysis [PDF]
Korean Journal of Anesthesiology, 2022 Background Diabetes is a risk factor for postoperative complications. Previous meta-analyses have shown that elevated glycated hemoglobin (HbA1c) levels are associated with postoperative complications in various surgical populations. However, this is the
Joanna K. L. Wong +5 more
doaj +1 more source
Molecular mechanisms of general anesthesia [PDF]
Korean Journal of Anesthesiology, 2010 General anesthetics produce a widespread neurodepression in the central nervous system by enhancing inhibitory neurotransmission and reducing excitatory neurotransmission.
Yong Son
doaj +1 more source
General Anesthetics Commonly Used for Laboratory Animals
Shiyan dongwu yu bijiao yixue, 2022 General anesthetics used for laboratory animals are mostly controlled drugs, and are subject to strict supervision by the competent government agency in China.
LU Xiao +5 more
doaj +1 more source
Shared structural mechanisms of general anesthetics and benzodiazepines
Nature, 2020 Most general anaesthetics and classical benzodiazepine drugs act through positive modulation of γ-aminobutyric acid type A (GABA A ) receptors to dampen neuronal activity in the brain 1 – 5 .
Jeong Joo Kim +9 more
semanticscholar +1 more source
Structural interplay of anesthetics and paralytics on muscle nicotinic receptors
Nature Communications, 2023 General anesthetics and neuromuscular blockers are used together during surgery to stabilize patients in an unconscious state. Anesthetics act mainly by potentiating inhibitory ion channels and inhibiting excitatory ion channels, with the net effect of ...
Umang Goswami +3 more
doaj +1 more source
Nature Communications, 2020 Metastasis can occur following surgical resection of solid tumors and metastasis is the main cause of cancer death. The role of anesthetics used during surgery in cancer metastasis and the underlying mechanism remains largely unknown.
Ru Li, Yujie Huang, Jun Lin
semanticscholar +1 more source
General Anesthetics Activate a Potent Central Pain-Suppression Circuit in the Amygdala
Nature Neuroscience, 2020 General anesthesia (GA) can produce analgesia (loss of pain) independent of inducing loss of consciousness, but the underlying mechanisms remain unclear. We hypothesized that GA suppresses pain in part by activating supraspinal analgesic circuits.
Thuy Hua +10 more
semanticscholar +1 more source
The effect of lidocaine on apoptotic neurodegeneration in the developing mouse brain [PDF]
Korean Journal of Anesthesiology, 2014 BackgroundGeneral anesthetics induce neuronal apoptosis in the immature brain. Regional anesthesia using local anesthetics can be an alternative to general anesthesia.
Ji-Hyun Lee +6 more
doaj +1 more source
The Effects of General Anesthetics on Synaptic Transmission
Current Neuropharmacology, 2020 General anesthetics are a class of drugs that target the central nervous system and are widely used for various medical procedures. General anesthetics produce many behavioral changes required for clinical intervention, including amnesia, hypnosis ...
Xuechao Hao +9 more
semanticscholar +1 more source
General Anesthetics on Immune System Cytokines: A Narrative Review Article
Anesthesiology and Pain Medicine, 2020 Context According to the previous studies, general anesthesia influences the immune system. Evaluating such impacts on the immune system helps to improve the management of anesthesia.
A. Jafarzadeh +4 more
semanticscholar +1 more source