Results 211 to 220 of about 74,037 (265)
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Evaluation of a General Anesthetic
JAMA, 1981Isoflurane is a nonflammable halogenated ether used as an inhalational anesthetic. It has physical, pharmacologic, and clinical properties similar to those of halothane and enflurane; however, it differs in important respects from both. It is a more potent muscle relaxant than halothane and does not have the CNS irritant properties of enflurane.
Michael H. M. Dykes, Harry W. Linde
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2006
Publisher Summary In surgical practice, the term general anesthesia (narcosis) presently refers to the condition of an organism with a reversible loss of consciousness at a controlled level of nervous system suppression. It includes components such as analgesia (absence of pain), amnesia (absence of memory), and suppression of reflexes such as ...
Victor J. Hruby, Ruben Vardanyan
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Publisher Summary In surgical practice, the term general anesthesia (narcosis) presently refers to the condition of an organism with a reversible loss of consciousness at a controlled level of nervous system suppression. It includes components such as analgesia (absence of pain), amnesia (absence of memory), and suppression of reflexes such as ...
Victor J. Hruby, Ruben Vardanyan
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Anaphylaxis to General Anesthetics
2010The incidence of hypersensitivity reactions to anesthetics is estimated 1 in 13,000 anesthetics up to 1 in 3,180. The rate of mortality ranges between 3 and 9%. 90% of reactions appear at anesthesia induction. Cardiovascular collapse and bronchospasm are more frequent in IgE-dependent reactions.
D. Anne Moneret-Vautrin +1 more
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Neurotoxicity of General Anesthetics: An Update
Current Pharmaceutical Design, 2012Though general anesthetics have now been used clinically for well over a century, both their mechanisms of action as well as the nature of any potentially neurotoxic side effects remain elusive. With roughly 234 million people undergoing surgery each year worldwide, it remains imperative that any potentially deleterious effects of anesthetics be ...
Zhongcong Xie, Phillip E. Vlisides
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General Anesthetic Techniques in Ruminants
Veterinary Clinics of North America: Food Animal Practice, 1996Sedation, anesthesia, protection of the airway during general anesthesia, and control of pain in the perioperative period are important considerations in the management of sheep, goats, and cattle. Though ruminants are classically considered farm animals and are often intended for the production of food and fiber, these species are used extensively in ...
Gwendolyn L. Carroll +1 more
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Antagonism of general anesthetics
International Congress Series, 2005Abstract Despite many research efforts on the mechanisms of anesthesia, there have been no reports on the anesthesia antagonists. It is well recognized that the dose–response curves of anesthetics are extremely steep. Availability of anesthesia antagonists would benefit anesthesia practice at emergency situations when the anesthesia becomes ...
Ikuo Ueda, Tsuneo Tatara, Hiroshi Kamaya
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General anesthetic allergy testing
Current Allergy and Asthma Reports, 2008Anaphylaxis in the setting of general anesthesia is a rare but potentially lethal event. The investigation of severe reactions is important for confirming the clinical diagnosis and identifying likely causative agents and safe agents that may be used in the future. Many comprehensive reports have described the testing protocol of individual specialized
Garry Donnan, Karl Bleasel, Gary Unglik
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General anesthetics and the developing brain
Current Opinion in Anaesthesiology, 2009General anesthetics and sedatives are used in millions of children every year to facilitate surgical procedures, imaging studies, and sedation in operating rooms, radiology suites, emergency departments, and ICUs. Mounting evidence from animal studies suggests that prolonged exposure to these compounds may induce widespread neuronal cell death and ...
Andreas W. Loepke, George K. Istaphanous
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2019
Anesthetising the older surgical patient present its own unique challenges. Heterogeneity is the most consistent feature of this age group and preoperative assessment and optimisation must take into account the varying comorbidities, extent of physiological ageing, frailty and the size of surgery which will determine patient outcome. Breast surgery can
Irwin Foo, Faisal Jafar
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Anesthetising the older surgical patient present its own unique challenges. Heterogeneity is the most consistent feature of this age group and preoperative assessment and optimisation must take into account the varying comorbidities, extent of physiological ageing, frailty and the size of surgery which will determine patient outcome. Breast surgery can
Irwin Foo, Faisal Jafar
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Clinical pharmacology of general anesthetics
Clinical Pharmacology & Therapeutics, 1967The past decade has seen great interest in the clinical pharmacology of general anesthetics. Recently introduced drugs, such as halothane or methoxyflurane, have already been studied in more detail than ether or nitrous oxide had been during the first century of their clinical use.
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