Results 251 to 260 of about 6,404,771 (353)

Selection of anesthetic agents for obstructive jaundice: An update for anesthesiologists. [PDF]

Medicine (Baltimore)
Li YQ, Zhou X, Cao Y, Long Y.
europepmc   +1 more source

Cortical Response to Acute Implantation of the Utah Optrode Array in Macaque Cortex

Advanced Healthcare Materials, EarlyView.
Delivering light deep into the brain over a large volume while causing minimal tissue damage is a major challenge for non‐human primate optogenetics. This study evaluates Utah Optrode Array designs in vivo, revealing how changes in shank geometry, surface texture, and insertion parameters minimize acute damage—offering a path toward high‐precision ...
Adrián Villamarin‐Ortiz, Christopher F. Reiche, Frederick Federer, Andrew M. Clark, John D. Rolston, Cristina Soto‐Sánchez, Eduardo Fernandez, Steve Blair, Alessandra Angelucci   +8 more
wiley   +1 more source

Anesthetic-mediated cardioprotection: from molecular mechanisms to clinical translation challenges. [PDF]

Front Physiol
Fu T, Jia X, Tang C, Yu D, Zhou H, Wang X, Liu S, Wu K.   +7 more
europepmc   +1 more source

Enhanced GABAergic actions resulting from the coapplication of the steroid 3α-hydroxy-5α-pregnane-11,20-dione (alfaxalone) with propofol or diazepam [PDF]

, 2018
Akk, Gustav, Cao, Lily Q, Chakrabarti, Shampuma, Evers, Alex S, Germann, Allison L, Mennerick, Steven, Montana, Michael C, Shin, Daniel J, Wozniak, David F, Yuede, Carla M   +9 more
core   +1 more source

Pulmonary Delivery of siRNA Anti‐TNFα‐loaded Lipid Nanoparticles for Rapid Recovery in Murine Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
In a murine model of acute lung injury, pulmonary administration of lipid nanoparticles carrying TNFα siRNA enables targeted delivery to immune cells. The study emphasises the importance of optimizing LNP distribution and delivery timing to improve therapeutic outcomes and develop emergency therapies for lung hyperinflammation.
Qinglin Wang, Jihana Achour, Laila Emam, Younes Louaguenouni, Catherine Cailleau, Françoise Mercier‐Nomé, Séverine Domenichini, Claudine Delomenie, Sezen Gul, Juliette Vergnaud, Nicolas Tsapis, Arnaud Mansart, Djillali Annane, Francois Fay, Elias Fattal   +14 more
wiley   +1 more source

Antibacterial activity of local anesthetics against multidrug-resistant bacteria in vitro. [PDF]

Am J Transl Res
Lee JS, Moon J, Lee JY, Kim HT, Park S, Park JW, Shin YD.   +6 more
europepmc   +1 more source

A Novel Sprayable Fibrinogen/Glycosaminoglycans/Collagen‐Based Bioink for Skin Wound Healing Applied by a Handheld Dual‐Head Airbrush

Advanced Healthcare Materials, EarlyView.
A dual‐head airbrush‐based spraying device, combined with a fibrinogen bioink enriched with glycosaminoglycans and collagen, enables the delivery of biomaterials and cells to promote wound healing. This system demonstrates effective skin regeneration in vitro and in vivo, with comparable results to autografts.
Paula Pleguezuelos‐Beltrán, Daniel Nieto‐García, Carlos Chocarro‐Wrona, Juan de Vicente, Patricia Gálvez‐Martín, José Manuel Entrena, Elena López‐Ruiz, Juan Antonio Marchal   +7 more
wiley   +1 more source

Comparison of Ciprofol-Based and Propofol-Based Total Intravenous Anesthesia on Postoperative Recovery Quality in Patients Undergoing Hysteroscopic Surgery: A Randomized Non-Inferiority Trial. [PDF]

Drug Des Devel Ther
Yang H, Yang Y, Huang Y, Liu T, Wang Y.
europepmc   +1 more source

Rolling Ultrasharp Microneedle Spheres Enable Topical Delivery of Biologics Through the Skin

Advanced Healthcare Materials, EarlyView.
Rolling ultraminiaturized microneedle spheres (RUMS), created via two‐photon polymerization, unlock effective and painless topical delivery of messenger RNA (mRNA) and drugs through the skin. By gently forming thousands of microscopic pores, RUMS boost skin permeability by up to 100‐fold.
Theocharis Nikiforos Iordanidis, Argyris Spyrou, Samantha Roudi, Fredrik J. Swartling, Göran Stemme, Samir EL Andaloussi, Niclas Roxhed   +6 more
wiley   +1 more source

Sevoflurane inhibition of the developmentally expressed neuronal sodium channel Na_v1.3. [PDF]

Sci Rep
Xiang J, Herold KF, Platholi J, Hemmings HC.   +3 more
europepmc   +1 more source