Results 61 to 70 of about 77,932 (186)

General Anesthetic Techniques in Swine

open access: yesVeterinary Clinics of North America: Food Animal Practice, 1996
General anesthesia techniques for swine can be challenging due to the animal's temperament, anatomic traits, physical condition, and the environment in which the clinician may be working. Taking these factors into consideration, this article provides specific information on preanesthetic considerations, venous catheterization, drug selection ...
P F, Moon, L J, Smith
openaire   +2 more sources

Intravenous anesthetics have differential effects on human potassium channels

open access: yesActa Biochimica et Biophysica Sinica
General anesthetics are widely used in the clinic and greatly promote the development of surgery. However, the incidence of cardiovascular and respiratory complications caused by general anesthetics is still high, and the underlying mechanisms remain ...
Tao Ying   +9 more
doaj   +1 more source

Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites. [PDF]

open access: yes, 2018
Voltage-gated sodium (NaV) channels are important targets of general anesthetics, including the intravenous anesthetic propofol. Electrophysiology studies on the prokaryotic NaV channel NaChBac have demonstrated that propofol promotes channel activation ...
Bondarenko, Vasyl   +12 more
core   +1 more source

A high-throughput approach for identification of novel general anesthetics. [PDF]

open access: yesPLoS ONE, 2009
Anesthetic development has been a largely empirical process. Recently, we described a GABAergic mimetic model system for anesthetic binding, based on apoferritin and an environment-sensitive fluorescent probe.
Wendy A Lea   +6 more
doaj   +1 more source

Scientometrics of anesthetic drugs and their techniques of administration, 1984–2013 [PDF]

open access: yes, 2015
The aim of this study was to assess progress in the field of anesthetic drugs over the past 30 years using scientometric indices: popularity indices (general and specific), representing the proportion of articles on a drug relative to all articles in the
Kissin, Igor, Vlassakov, Kamen V
core   +1 more source

ANESTHETIC, ANALGETIC, HYPNOTIC – ARE THE TERMS IMPORTANT?

open access: yesВестник анестезиологии и реаниматологии, 2017
The review is devoted to pharmacology of the general anesthesia in the light of current understanding of this event and as a medical technique. The discussion covers the classification of medications used for general anesthesia basing on action mechanisms
A. E. Karelov   +2 more
doaj   +1 more source

Metabifurcation analysis of a mean field model of the cortex

open access: yes, 2010
Mean field models (MFMs) of cortical tissue incorporate salient features of neural masses to model activity at the population level. One of the common aspects of MFM descriptions is the presence of a high dimensional parameter space capturing ...
Bojak, Ingo   +3 more
core   +2 more sources

Perioperative and anesthetic deaths: toxicological and medico legal aspects [PDF]

open access: yes, 2019
Background: Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology.
Argo A.   +5 more
core   +1 more source

Electrostatic Contributions of Aromatic Residues in the Local Anesthetic Receptor of Voltage-Gated Sodium Channels [PDF]

open access: yes, 2008
Antiarrhythmics, anticonvulsants, and local anesthetics target voltage-gated sodium channels, decreasing excitability of nerve and muscle cells. Channel inhibition by members of this family of cationic, hydrophobic drugs relies on the presence of highly ...
Ahern, Christopher A.   +3 more
core   +2 more sources

Research progress on mitochondrial mechanisms of sensitivity to inhalational anesthetics

open access: yesZhongguo linchuang yanjiu
Experimental animals and people have different sensitivity to inhalational anesthetics, which is related to the depth of anesthesia during general anesthesia and the perioperative safety of patients.
CHENG Sijing*, WEI Yiyong, WANG Haiying
doaj   +1 more source

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