General Anesthetic Techniques in Swine
General anesthesia techniques for swine can be challenging due to the animal's temperament, anatomic traits, physical condition, and the environment in which the clinician may be working. Taking these factors into consideration, this article provides specific information on preanesthetic considerations, venous catheterization, drug selection ...
P F, Moon, L J, Smith
openaire +2 more sources
Intravenous anesthetics have differential effects on human potassium channels
General anesthetics are widely used in the clinic and greatly promote the development of surgery. However, the incidence of cardiovascular and respiratory complications caused by general anesthetics is still high, and the underlying mechanisms remain ...
Tao Ying +9 more
doaj +1 more source
Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites. [PDF]
Voltage-gated sodium (NaV) channels are important targets of general anesthetics, including the intravenous anesthetic propofol. Electrophysiology studies on the prokaryotic NaV channel NaChBac have demonstrated that propofol promotes channel activation ...
Bondarenko, Vasyl +12 more
core +1 more source
A high-throughput approach for identification of novel general anesthetics. [PDF]
Anesthetic development has been a largely empirical process. Recently, we described a GABAergic mimetic model system for anesthetic binding, based on apoferritin and an environment-sensitive fluorescent probe.
Wendy A Lea +6 more
doaj +1 more source
Scientometrics of anesthetic drugs and their techniques of administration, 1984–2013 [PDF]
The aim of this study was to assess progress in the field of anesthetic drugs over the past 30 years using scientometric indices: popularity indices (general and specific), representing the proportion of articles on a drug relative to all articles in the
Kissin, Igor, Vlassakov, Kamen V
core +1 more source
ANESTHETIC, ANALGETIC, HYPNOTIC – ARE THE TERMS IMPORTANT?
The review is devoted to pharmacology of the general anesthesia in the light of current understanding of this event and as a medical technique. The discussion covers the classification of medications used for general anesthesia basing on action mechanisms
A. E. Karelov +2 more
doaj +1 more source
Metabifurcation analysis of a mean field model of the cortex
Mean field models (MFMs) of cortical tissue incorporate salient features of neural masses to model activity at the population level. One of the common aspects of MFM descriptions is the presence of a high dimensional parameter space capturing ...
Bojak, Ingo +3 more
core +2 more sources
Perioperative and anesthetic deaths: toxicological and medico legal aspects [PDF]
Background: Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology.
Argo A. +5 more
core +1 more source
Electrostatic Contributions of Aromatic Residues in the Local Anesthetic Receptor of Voltage-Gated Sodium Channels [PDF]
Antiarrhythmics, anticonvulsants, and local anesthetics target voltage-gated sodium channels, decreasing excitability of nerve and muscle cells. Channel inhibition by members of this family of cationic, hydrophobic drugs relies on the presence of highly ...
Ahern, Christopher A. +3 more
core +2 more sources
Research progress on mitochondrial mechanisms of sensitivity to inhalational anesthetics
Experimental animals and people have different sensitivity to inhalational anesthetics, which is related to the depth of anesthesia during general anesthesia and the perioperative safety of patients.
CHENG Sijing*, WEI Yiyong, WANG Haiying
doaj +1 more source

