Results 271 to 280 of about 736,541 (316)

Safety of Intravenous and Inhalation Anesthetics

2013
9.2 Determination of Safety of Inhalation Anesthetics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 279 9.2.1 General Considerations . . . . . . . . . . . . . . . . . . . . . . . . . . . . 279 9.2.2 Safety Margin of Inhalation Anesthetics . . . . . . . . . .
openaire   +3 more sources

Local anesthetics systemic toxicity association with exparel (bupivacaine liposome)- a pharmacovigilance evaluation

Expert Opinion on Drug Safety, 2018
Background: Local anesthetic systemic toxicity (last) is a rare life threatening complication usually from intra-arterial or intravenous injection leading to systemic absorption of regional anesthesia drug.
N. Aggarwal
semanticscholar   +1 more source

Intravenous anesthetics differentially reduce neurotransmission damage caused by oxygen-glucose deprivation in rat hippocampal slices in correlation with N-methyl-d-aspartate receptor inhibition

Critical Care Medicine, 2001
ObjectiveTo examine the relation between the effect of intravenous anesthetics on ischemic neurotransmission damage and their actions on N-methyl-d-aspartate (NMDA) receptors in an in vitro cerebral ischemic model.
R. Zhan, S. Qi, Chaoran Wu, H. Fujihara, K. Taga, K. Shimoji   +5 more
semanticscholar   +1 more source

PHARMACOLOGY OF INTRAVENOUS LOCAL ANESTHETICS

Acta Anaesthesiologica Scandinavica, 1969
SUMMARYThe systemic effects of local anesthetics should be regarded as with other drugs. The central nervous system can be stimulated or depressed. The depressant action may be useful or dangerous depending on the severity of the situation. The cardiovascular effects are depressant in nature and are useful in antiarrhythmic therapy.
openaire   +3 more sources

Eutectic Mixture of Local Anesthetics Reduces Pain During Intravenous Catheter Insertion in the Pediatric Patient

The Clinical Journal of Pain, 2001
ObjectiveThe objective of this study was to explore the relation between the application of a mixture of lidocaine/prilocaine cream (eutectic mixture of local anesthetics [EMLA]) before intravenous cannula insertion and perceived pain in the pediatric ...
A. Cordoni, L. Cordoni
semanticscholar   +1 more source

Acute Cardiovascular Toxicity of Intravenous Amide Local Anesthetics in Anesthetized Ventilated Dogs

Anesthesia and Analgesia, 1982
The acute intravenous cardiovascular toxicity of five amide local anesthetic agents was studied in intact, ventilated dogs anesthetized with pentobarbital. Minimal changes in various cardiovascular functions were seen at doses of 0.3 to 3.0 mg/kg.
P. Liu, H. Feldman, B. Covino, R. Giasi, B. Covino   +4 more
semanticscholar   +1 more source

Effects of intravenous anesthetics on interleukin (IL)‐6 and IL‐10 production by lipopolysaccharide‐stimulated mononuclear cells from healthy volunteers

Acta Anaesthesiologica Scandinavica, 2002
Background: Surgical trauma has been shown to augment the plasma concentrations of proinflammatory cytokines, which are important mediators of host defense mechanisms and the systemic inflammatory response syndrome (SIRS).
M. Takaono, T. Yogosawa, M. Okawa-Takatsuji, Shinichi Aotsuka   +3 more
semanticscholar   +1 more source

Facilitation of Serotonergic Activity and Amnesia in Rats Caused by Intravenous Anesthetics

Anesthesiology, 2005
Background:Midazolam and propofol often provoke retrograde amnesia after recovery from anesthesia in humans. Because an increase in central serotonergic activity impairs learning and memory, the authors examined the relation between changes in the ...
K. Semba, N. Adachi, T. Arai
semanticscholar   +1 more source

Dexmedetomidine as a Total Intravenous Anesthetic Agent

Anesthesiology, 2004
DEXMEDETOMIDINE is a highly selective α 2 adrenoceptor agonist that has sedative and analgesic properties with associated reduction in opioid and anesthetic requirements. 1-11 One significant advantage of dexmedetomidine is that in the clinical dose range there is no respiratory depression. 12-14 The agonistic action on the α 2 adrenoceptors in the
David L. Luterman, Michael A. E. Ramsay
openaire   +3 more sources

Intravenous Anesthetics in the Pulmonary Circulation

2000
Intravenous anesthetics in either bolus or constant infusion may be used to produce induction or maintenance of anesthesia. Examples of these anesthetics are ultra-short-acting thiobarbiturates, propofol, etomidate, and ketamine. Of the four, propofol and ketamine possess significant pulmonary effects.
Alan D. Kaye, Bobby D. Nossaman, Philip J. Kadowitz   +2 more
openaire   +2 more sources