Results 21 to 30 of about 736,541 (316)

Volatile anesthetics versus total intravenous anesthesia in patients undergoing coronary artery bypass grafting: An updated meta-analysis and trial sequential analysis of randomized controlled trials

PLoS ONE, 2019
Background The benefits of volatile anesthetics in coronary artery bypass grafting (CABG) patients remain controversial. We aimed to conduct an updated meta-analysis to assess whether the use of volatile anesthetics during CABG could reduce mortality and
X. Jiao, Xue-mei Lin, X. Ni, Hailong Li, Chuan Zhang, Chun-song Yang, Hao-Xin Song, Qiusha Yi, Ling-Li Zhang   +8 more
semanticscholar   +1 more source

INHALATION SEDATION IN THE PATIENTS AFTER CARDIAC SURGERY IN INTENSIVE CARE UNITS

Вестник анестезиологии и реаниматологии, 2018
From the time when special tools for delivery of volatile anesthetics in the intensive care units (ICU) became available, inhalation sedation is getting more and more popular among emergency physicians.
V. V. Likhvantsev, O. A. Grebenchikov, Yu. V. Skripkin, O. N. Ulitkina, F. F. Bershadskiy, E. M. Stroiteleva   +5 more
doaj   +1 more source

The thermodynamics of general and local anesthesia [PDF]

Biophys. J. 2014, 106: 2143-2156, 2014
General anesthetics are known to cause depression of the freezing point of transitions in biomembranes. This is a consequence of ideal mixing of the anesthetic drugs in the membrane fluid phase and exclusion from the solid phase. Such a generic law provides physical justification of the famous Meyer-Overton rule.
arxiv   +1 more source

Intravenous versus Volatile Anesthetic Effects on Postoperative Cognition in Elderly Patients Undergoing Laparoscopic Abdominal Surgery.

Anesthesiology, 2021
BACKGROUND Delayed neurocognitive recovery after surgery is associated with poor outcome. Most surgeries require general anesthesia, of which sevoflurane and propofol are the most commonly used inhalational and intravenous anesthetics. The authors tested
Yujuan Li, Dongtai Chen, Han-bing Wang, Zhi Wang, Furong Song, Hui Li, L. Ling, Zhiwen Shen, Chuwen Hu, Jun Peng, Wei-Xing Li, W. Xing, Jiahao Pan, Hua-geng Liang, Qiao-ling Zhou, J. Cai, Ziqing He, S. Peng, W. Zeng, Zhiyi Zuo   +19 more
semanticscholar   +1 more source

Lipid Emulsion for Local Anesthetic Systemic Toxicity

Anesthesiology Research and Practice, 2012
The accidental overdose of local anesthetics may prove fatal. The commonly used amide local anesthetics have varying adverse effects on the myocardium, and beyond a certain dose all are capable of causing death.
Sarah Ciechanowicz, Vinod Patil
doaj   +1 more source

Structural interplay of anesthetics and paralytics on muscle nicotinic receptors

Nature Communications, 2023
General anesthetics and neuromuscular blockers are used together during surgery to stabilize patients in an unconscious state. Anesthetics act mainly by potentiating inhibitory ion channels and inhibiting excitatory ion channels, with the net effect of ...
Umang Goswami, Md Mahfuzur Rahman, Jinfeng Teng, Ryan E. Hibbs   +3 more
doaj   +1 more source

anesthetic: nested sampling visualisation [PDF]

Journal of Open Source Software, 2019, 4(37), 1414, 2019
anesthetic is a Python package for processing nested sampling runs, and will be useful for any scientist or statistician who uses nested sampling software. anesthetic unifies many existing tools and techniques in an extensible framework that is intuitive for users familiar with the standard Python packages, namely NumPy, SciPy, Matplotlib and pandas.
arxiv   +1 more source

Shared structural mechanisms of general anesthetics and benzodiazepines

Nature, 2020
Most general anaesthetics and classical benzodiazepine drugs act through positive modulation of γ-aminobutyric acid type A (GABA A ) receptors to dampen neuronal activity in the brain 1 – 5 .
Jeong Joo Kim, A. Gharpure, J. Teng, Y. Zhuang, R. Howard, Shaotong Zhu, C. Noviello, R. M. Walsh, E. Lindahl, R. Hibbs   +9 more
semanticscholar   +1 more source

Effects of Anesthetics on Barrier Tissue Function

Journal of Immunology Research, 2019
Anesthetics have long been proven to have additional effects other than anesthesia on different organs and tissues of the human body. Barrier tissues play critical roles in human health and diseases, yet the impacts of anesthetics on barrier tissues are ...
Fujing Wang, Yanhui Li, Changlei Cui, Zhaoping Xue, Haichun Ma   +4 more
doaj   +1 more source

Differential role of intravenous anesthetics in colorectal cancer progression: implications for clinical application

OncoTarget, 2016
Anesthetics are unavoidable to colorectal cancer (CRC) patients who underwent surgical treatment. Thus, the molecular mechanisms underlying the role of the intravenous anesthetics in CRC metastasis are still unclear.
Fengliu Deng, Mingwen Ouyang, Xiaofei Wang, Xue-qing Yao, Yeming Chen, Taoliangshan Tao, Xuegang Sun, Lijun Xu, Jing Tang, Liang Zhao   +9 more
semanticscholar   +1 more source