Results 131 to 140 of about 5,479,760 (341)
Huli yanjiuObjectiveTo explore the influencing factors of pediatric nurses' willingness to adopt local anesthetics in clinical practice.MethodsA total of 251 pediatric nurses from 10 hospitals in Sichuan province were surveyed by a self⁃designed survey ...
ZHAO Liping +3 more
doaj
Mydriasis mediated by local anesthetics: an unexpected adverse event or new therapeutic indication?
Therapeutic Advances in Drug SafetyThe increasing off-label use of medications needs a robust pharmacovigilance system. This is particularly crucial given the abundance of scientific data that can be harnessed to ensure a product’s safety.
Homero Contreras-Salinas +4 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
, 1986 P(論文)Abnormal reactions often occur under local anesthesia during dental treatment, and occasionally there are allergic reactions to local anesthetics or to its additives. This paper presents definitions, mechanism and symptons of such allergy and a safe
新家, 昇, 22136
core
Neutrophil‐Mimetic MRI Enables Ultra‐Early Detection of Vascular Inflammation After Stroke
Advanced Healthcare Materials, EarlyView.In this study, we developed neutrophil‐mimetic MRI probes that detect ultra‐early neuroinflammation following ischemic stroke by targeting E‐selectin. Within seconds of their injection, these microparticles mimic initial leukocyte adhesion to the activated cerebral endothelium.
Marion Isabelle Morvan +17 more
wiley +1 more source
Non anesthetic action of local anesthetics
, 2013 Local anesthetics are not only used as drugs to block the sodium channel to provide analgesi and anti-arrhythmic action. The purpose of this review is to highlight the new indications and limitations of this class of drugs. Recent research has focused on
ALAIN BORGEAT, BORGEAT, ALAIN
core
Atomic Layer Deposition Processes: Versatile Platforms for Engineering ZnO‐Chitosan Biointerfaces
Advanced Healthcare Materials, EarlyView.Vapour phase metalation (VPM), multiplied pulsed vapour phase infiltration (MPI), and O2 plasma‑enhanced atomic layer deposition (PEALD) tailor Zn–chitosan (Zn‑CS) films. PEALD improves wettability and biocompatibility. MPI enhances semiconductor behavior. Antiseptic selectivity: VPM → E. coli; MPI → H. pylori.
Mabel Moreno +17 more
wiley +1 more source
Journal of Ege University School of Dentistry, 2019 Derya Karasu +3 more
semanticscholar +1 more source
DETERMINATION BY^1H-NMR OF BINDING SITES OF LOCAL ANESTHETICS ON LIPID BILAYER MEMBRANE MODEL
, 1994 P(論文)局所麻酔薬の作用機序についてはさまざまな仮説があるが,どの仮説も十分な説明をしていない。そこで我々は核磁気共鳴装置(NMR)を用いて,局所麻酔薬と神経膜モデルであるリン脂質二重膜との結合状態を検索した。この結果,局所麻酔薬分子中にある窒素原子とリン脂質二重膜の外側にある親水性部分の酸素原子とが静電結合をおこすことが分かった。また我々が作用持続時間の延長を目的に合成した,リドカインのエステル誘導体では窒素原子との結合に加えて,エステルカルボニル部分の酸素原子でも膜と結合することもわかった。さらに,
23966 +7 more
core
Advanced Healthcare Materials, EarlyView.Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha +9 more
wiley +1 more source