Results 11 to 20 of about 5,479,760 (341)
Safety of local anesthetics, [PDF]
Anais Brasileiros de Dermatologia, 2020 Local anesthetics are essential medications for the conduction of dermatological procedures. They stop the depolarization of nerve fibers and are divided into two main categories, the amide and ester types.
Ana Carolina Figueiredo Pereira Cherobin +1 more
doaj +6 more sources
Local anesthetics elicit immune-dependent anticancer effects
Journal for ImmunoTherapy of Cancer, 2022 Background Retrospective clinical trials reported a reduced local relapse rate, as well as improved overall survival after injection of local anesthetics during cancer surgery. Here, we investigated the anticancer effects of six local anesthetics used in
Shuai Zhang +14 more
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Stem Cell Research & Therapy, 2021 Background A large number of preclinical studies have shown that local anesthetics have a direct inhibitory effect on tumor biological activities, including cell survival, proliferation, migration, and invasion. There are few studies on the role of local
Xiaoqing Fan +7 more
doaj +2 more sources
Mechanisms of Cancer Inhibition by Local Anesthetics
Frontiers in Pharmacology, 2021 The use of local anesthetics during surgical treatment of cancer patients is an important part of perioperative analgesia. In recent years, it has been showed that local anesthetics can directly or indirectly affect the progression of tumors.
Yiguo Zhang +7 more
doaj +2 more sources
BMC Anesthesiology, 2020 Background Retrospective analysis and pre-clinical studies suggest that local anesthetics have anti-tumoral effects. However, the association between cancer recurrence and the use of local anesthesia is inconclusive and most reports are based on single ...
Guanhua Zhu +3 more
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Effects of local anesthetics on breast cancer cell viability and migration
BMC Cancer, 2018 Background Breast cancer accounts for nearly a quarter of all cancers in women worldwide, and more than 90% of women diagnosed with breast cancer undergo mastectomy or breast-conserving surgery.
Ru Li +5 more
doaj +2 more sources
Chiral Aspects of Local Anesthetics
Molecules, 2020 Thanks to the progress made in chemical technology (particularly in the methodologies of stereoselective syntheses and analyses) along with regulatory measures, the number of new chiral drugs registered in the form of pure enantiomers has increased over ...
Ružena Čižmáriková +4 more
doaj +2 more sources
Local anesthetics for brain tumor resection: current perspectives
Local and Regional Anesthesia, 2018 This review summarizes the added value of local anesthetics in patients undergoing craniotomy for brain tumor resection, which is a procedure that is carried out frequently in neurosurgical practice.
J. Potters, M. Klimek
semanticscholar +2 more sources
On controversial issues of systemic toxicity of local anesthetics
Вестник анестезиологии и реаниматологии, 2020 The letter draws attention to the provisions on the use of fat emulsion when systemic toxicity of local anesthetics develops that was published in the article titled Disputed Issues of Systemic Toxicity of Local Anesthetics.
R. E. Lakhin
doaj +3 more sources
Allergy to local anesthetics: Reality or myth?
Presse medicale, 2016 International audienceThe incidence of allergic reactions to local anesthetics is low. Most cases involve a psychogenic reaction rather than an allergic reaction.
J. Malinovsky +4 more
semanticscholar +2 more sources