Results 21 to 30 of about 4,774,452 (329)

Electrostatic Contributions of Aromatic Residues in the Local Anesthetic Receptor of Voltage-Gated Sodium Channels [PDF]

, 2008
Antiarrhythmics, anticonvulsants, and local anesthetics target voltage-gated sodium channels, decreasing excitability of nerve and muscle cells. Channel inhibition by members of this family of cationic, hydrophobic drugs relies on the presence of highly ...
Ahern, Christopher A., Dougherty, Dennis A., Eastwood, Amy L., Horn, Richard   +3 more
core   +2 more sources

Minimum anesthetic volume in regional anesthesia by using ultrasound-guidance

Revista Brasileira de Anestesiologia, 2016
The ultrasound guidance in regional anesthesia ensures the visualization of needle placement and the spread of Local Anesthetics. Over the past few years there was a substantial interest in determining the Minimum Effective Anesthetic Volume necessary to
Alessandro Di Filippo, Silvia Falsini, Chiara Adembri   +2 more
doaj   +3 more sources

Transient neurologic symptoms following spinal anesthesia with isobaric mepivacaine: A decade of experience at Toronto Western Hospital [PDF]

, 2018
Background: Transient neurologic symptoms (TNSs) can be distressing for patients and providers following uneventful spinal anesthesia. Spinal mepivacaine may be less commonly associated with TNS than lidocaine; however, reported rates of TNS with ...
Abdallah, Faraj W., Behboudi, Minou, Brull, Richard, MacFarlane, Alan, Sankar, Ashwin   +4 more
core   +2 more sources

Cytotoxicity of Local Anesthetics on Bone, Joint, and Muscle Tissues: A Narrative Review of the Current Literature

Journal of Pain Research, 2023
Kaiwen Zhang, Meihong Li, Wenlong Yao, Li Wan Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of ChinaCorrespondence: Li Wan, Department of Anaesthesiology ...
Zhang K, Li M, Yao W, Wan L
doaj  

Lipid Emulsion for Local Anesthetic Systemic Toxicity

Anesthesiology Research and Practice, 2012
The accidental overdose of local anesthetics may prove fatal. The commonly used amide local anesthetics have varying adverse effects on the myocardium, and beyond a certain dose all are capable of causing death.
Sarah Ciechanowicz, Vinod Patil
doaj   +1 more source

Fast glycorrhachia and cerebrospinal fluid protein as predictors of sensory block in anesthesia with subarachnoid Ropivacaine [PDF]

, 2016
BACKGROUND: Identify if glycorrhachia and cerebrospinal fluid protein could influence the time of sensory block to T10, the duration and the metameric block's level, after a standard dose of Ropivacaine. METHODS: 80 patients, ASA I - III undergoing to
COLLINI, Saul, DE SIO, SIMONE, MERLIN, PAMELA, PACELLA, Elena, PACELLA, FERNANDA, Troisi, F   +5 more
core   +1 more source

Preparação, caracterização e avaliação in vitro de microesferas de bupivacaína em excesso enantiomérico de 50% (S75-R25) Preparación, caracterización y evaluación in vitro de microesferas de bupivacaina en exceso enantiomérico de 50% (S75-R25) Preparation, characterization and in vitro evaluation of 50% enantiomeric excess bupivacaine (S75-R25)-loaded microspheres

Revista Brasileira de Anestesiologia, 2008
JUSTIFICATIVA E OBJETIVOS: As microesferas podem ser utilizadas como um sistema de liberação controlada para prolongar a ação de anestésicos locais.
Pedro Paulo Tanaka, Jean Pierre Estèbe, Richard Campos, François Chevanne, Pascal Le Corre, Sérgio Bernardo Tenório, Maria Fernanda Torres   +6 more
doaj   +1 more source

Monosynaptic Functional Connectivity in Cerebral Cortex During Wakefulness and Under Graded Levels of Anesthesia [PDF]

, 2012
The balance between excitation and inhibition is considered to be of significant importance for neural computation and cognitive function. Excitatory and inhibitory functional connectivity in intact cortical neuronal networks in wakefulness and graded ...
Diba, Kamran, Hudetz, Anthony G., Pillay, Siveshigan, Ropella, Kristina M., Vizuete, Jeannette A.   +4 more
core   +3 more sources