Results 71 to 80 of about 330,973 (257)

Kidney Fibrosis In Vitro and In Vivo Models: Path Toward Physiologically Relevant Humanized Models

Advanced Healthcare Materials, EarlyView.
This review discusses kidney diseases with a focus on kidney fibrosis and the models currently used. It highlights the limitations of animal and 2D in vitro models in replicating human kidney anatomy and physiology. Consequently, there is a significant need for humanized 3D in vitro models, such as 3D cell aggregates, membranes and hydrogels, on‐chip ...
Gabriele Addario, Lorenzo Moroni, Carlos Mota   +2 more
wiley   +1 more source

Monosynaptic Functional Connectivity in Cerebral Cortex During Wakefulness and Under Graded Levels of Anesthesia [PDF]

, 2012
The balance between excitation and inhibition is considered to be of significant importance for neural computation and cognitive function. Excitatory and inhibitory functional connectivity in intact cortical neuronal networks in wakefulness and graded ...
Diba, Kamran, Hudetz, Anthony G., Pillay, Siveshigan, Ropella, Kristina M., Vizuete, Jeannette A.   +4 more
core   +3 more sources

Thermally Drawn Shape and Stiffness Programmable Fibers for Medical Devices

Advanced Healthcare Materials, EarlyView.
Thermal drawing technique is adapted to fabricate Shape Memory Polymer Fibers (SMPFs) with programmable stiffness and shape. Multilumen and multimaterial SMPFs are developed for innovative medical devices: stiffness adjustable catheters, body temperature softening neural interfaces, and shape programmable cochlear implants.
Jiwoo Choi, Qindong Zheng, Mohamed E. M. K. Abdelaziz, Thomas Dysli, Daniel Bautista‐Salinas, Andreas Leber, Shan Jiang, Jianan Zhang, Ali Anil Demircali, Jinshi Zhao, Yue Liu, Nick W. F. Linton, Fabien Sorin, Xiaoting Jia, Eric M. Yeatman, Guang‐Zhong Yang, Burak Temelkuran   +16 more
wiley   +1 more source

Nitrogen‐Doped Ultrananocrystalline Diamond – Optoelectronic Biointerface for Wireless Neuronal Stimulation

Advanced Healthcare Materials, EarlyView.
Researchers demonstrate a diamond‐based, wireless biointerface capable of generating safe capacitive current under pulsed light illumination in the visible and near‐infrared light region. This biointerface is long‐lasting and the first among diamond‐based electrodes capable of optically‐controlled, non‐genetic modulation of intracellular calcium ...
Yue Yao, Arman Ahnood, Andre Chambers, Wei Tong, Steven Prawer   +4 more
wiley   +1 more source

Action potential as a pressure pulse propagating in the axoplasm [PDF]

arXiv, 2009
We suggest that the propagation of the action potential is driven by a pressure pulse propagating in the axoplasm along the axon length. The pressure pulse mechanically activates Na ion channels embedded in the axon membrane. This activation initiates the development of a local membrane voltage spike, as in the Hodgkin-Huxley model of the action ...
arxiv  

Local anesthetic infiltration vs. nervous blocks in face’s skin lesions: what’s new [PDF]

, 2018
Skin tumors are the most common type of cancer. They are localized throughout the body, more frequently in those regions chronically exposed to sun, like face, scalp and neck, compromising aesthetic appearance.
Arrico, L., Brancadoro, D., Collini, S., Grippaudo, F., Troisi, F.   +4 more
core  

Allergic Reactions to Local Anesthetics in Dental Patients: Analysis of Intracutaneous and Challenge Tests [PDF]

Some dental patients have histories of adverse reactions to local anesthesia. The aim of the present study was to investigate the frequency of allergy to local anesthetics of dental patients who had histories of adverse reactions to local anesthesia ...
Adriani J, Adriani J, Aldrete JA, Ayako Jinzenji, Barbaud A, Berkun Y, Fisher MM, Fisher MM, Giovannitti JA, Green SM, Hitoshi Higuchi, Kazuo Mukae, Kelly KJ, Mai Sakaguchi, Malamed SF, Michiyo Suda, Minako Ishii, Schatz M, Schwartz HJ, Shigeru Maeda, Takuya Miyawaki, Thyssen JP, Tomoko Hayashi, Wildsmith JA, Yoshihisa Watanabe, Yukiko Arai, Yumiko Tomoyasu   +26 more
core   +2 more sources

CircAars‐Engineered ADSCs Facilitate Maxillofacial Bone Defects Repair Via Synergistic Capability of Osteogenic Differentiation, Macrophage Polarization and Angiogenesis

Advanced Healthcare Materials, EarlyView.
Schematic representation of circAars‐engineered‐ADSCs incorporated into GelMA scaffolds for craniomaxillofacial bone regeneration. CircAars‐engineered ADSCs embedded in GelMA scaffolds enhance the repair of critical‐sized bone defects by binding miR‐128‐3p in the cytoplasm, thereby inhibiting its activity.
Yi He, Yunyang Lu, Runze Li, Yuquan Tang, Weidong Du, Lejia Zhang, Jie Wu, Kechen Li, Weijie Zhuang, Shiyu Lv, Yaoling Han, Bailong Tao, Feilong Deng, Wei Zhao, Dongsheng Yu   +14 more
wiley   +1 more source

Information capacity and transmission are maximized in balanced cortical networks with neuronal avalanches [PDF]

The Journal of Neuroscience, January 5, 2011 31(01), 2010
The repertoire of neural activity patterns that a cortical network can produce constrains the network's ability to transfer and process information. Here, we measured activity patterns obtained from multi-site local field potential (LFP) recordings in cortex cultures, urethane anesthetized rats, and awake macaque monkeys.
arxiv  

SENSORY REGRESSION TIME FROM SUBARACHNOID BLOCK WITH HYPERBARIC 0.75% BUPIVACAINE IN THE OBESE PATIENT [PDF]

, 1989
The purpose of this study was to determine if obese patients have a different sensory regression time from subarachnoid block than non-obese patients using hyperbaric 0.75% bupivacaine. A quasi-experimental design was used. Twenty patients were separated
Hilton, George Leslie
core   +1 more source