Results 231 to 240 of about 302,831 (404)

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

Mydriasis mediated by local anesthetics: an unexpected adverse event or new therapeutic indication? [PDF]

Ther Adv Drug Saf
Contreras-Salinas H, Vázquez-Beltrán JC, Romero-López MS, Olvera-Montaño O, Rodríguez-Herrera LY.   +4 more
europepmc   +1 more source

Best Anesthetics for Assessing Left Ventricular Systolic Function by Echocardiography in Mice

American Journal of Physiology. Heart and Circulatory Physiology, 2015
R. Pachon, B. Scharf, Lin Yan, D. Vatner, S. Vatner   +4 more
semanticscholar   +1 more source

Eco‐Fabricated Nanowave‐Textured Implants Drive Microtubule‐Assisted Nuclear Mechanotransduction and Chromatin Modification: Biophysical Priming for Osteogenesis and Bone Regeneration

Advanced Functional Materials, EarlyView.
Eco‐friendly nanowave‐textured implants produced via femtosecond laser fabrication enhance bone regeneration by orchestrating a precise mechanotransduction cascade. This nanotopography directs mesenchymal stem cell alignment and cytoskeletal organization, triggering changes in nuclear shape and chromatin acetylation that prime cells for osteogenesis ...
Bosu Jeong, Ji‐Young Yoon, Junyong Ahn, Byunghak Lee, Sung‐Min Park, Jae‐Heon Kim, Buuvee Bayarkhangai, Yu Jin Kim, Sak Lee, Jonathan C. Knowles, Moon‐Young Kim, DongJun Lee, Sang‐Hoon Rhee, Hae‐Hyoung Lee, Hae‐Won Kim, Jung‐Hwan Lee   +15 more
wiley   +1 more source

Convergent effects of different anesthetics on changes in phase alignment of cortical oscillations. [PDF]

Cell Rep
Bardon AG, Ballesteros JJ, Brincat SL, Roy JE, Mahnke MK, Ishizawa Y, Brown EN, Miller EK.   +7 more
europepmc   +1 more source

Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration

Advanced Functional Materials, EarlyView.
A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo, Zaijin Tao, Zhenzhen Dai, Yinghua Gao, Chengzhen Chu, Cunyi Fan, Shen Liu, Xin Ma, Fangchun Jin, Zhengwei You, Jia Jiang   +10 more
wiley   +1 more source

Efficacy of continuous epidural anesthetics and steroids infusion for management of acute herpes zoster and postherpetic neuralgia: a retrospective study. [PDF]

Front Neurol
Dou X, Guan X, Li C, Qin W, Zhang Y, Li Y, Han B, Wu C, Chen Y, Wang L, Mao P, Zhou L, Fan B.   +12 more
europepmc   +1 more source

THE CHOICE OF ANESTHETIC IN OPERATING FOR ABSCEDD OF THE LUNG

, 1914
FRED T. MURPHY
openalex   +2 more sources

Comparative Study of Anesthetic Agents on Propulsive Motility of the Small Intestine [PDF]

, 1947
Edward J. Van Liere, J. Clifford Stickney, DAVID W. NORTHRUP   +2 more
openalex   +1 more source

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

Advanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires, Ezra Gordon, Heikyung Suh, Darrell J. Irvine, Paula T. Hammond   +4 more
wiley   +1 more source