Results 1 to 10 of about 218,062 (252)

Isoflurane promotes phagocytosis of apoptotic neutrophils through AMPK-mediated ADAM17/Mer signaling. [PDF]

PLoS ONE, 2017
A patient's recovery from lung inflammatory injury or development of multi-system organ failure is determined by the host's ability to resolve inflammation and repair tissue damage, both of which require the clearance of apoptotic neutrophils by ...
Xueke Du, Chunling Jiang, Yang Lv, Randal O Dull, You-Yang Zhao, David E Schwartz, Guochang Hu   +6 more
doaj   +1 more source

Do the Manual or Computer-Controlled Flowmeters Generate Similar Isoflurane Concentrations in Tafonius?

Frontiers in Veterinary Science, 2019
Introduction: Tafonius is an anesthesia machine with computer-controlled monitor and ventilator. We compared the isoflurane fluctuations in the circuit with manual (MF) or computer-driven (CF) flowmeters, investigated the origin of the differences and ...
Mathieu Raillard, Mathieu Raillard, Olivier Levionnois, Paul MacFarlane   +3 more
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A pilot study on midazolam sedation for murine echocardiography: A potential alternative to isoflurane anesthesia and awake imaging

Physiological Reports
Isoflurane anesthesia is often used to facilitate murine echocardiography, but can suppress cardiac function. Awake imaging avoids pharmacological interference, but can induce sympathetic activation. In this Midazolam sedation.
Bart Jacobs, Sarah Derde, Lies Langouche, Jan D'hooge, Nadia Salerno, Sandro Queirós, Greet Van den Berghe, Annette Caenen, Jan Gunst   +8 more
doaj   +1 more source

Isoflurane depresses hippocampal CA1 glutamate nerve terminals without inhibiting fiber volleys

BMC Neuroscience, 2006
Background Anesthetic-induced CNS depression is thought to involve reduction of glutamate release from nerve terminals. Recent studies suggest that isoflurane reduces glutamate release by block of Na channels.
MacIver M Bruce, Winegar Bruce D
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Isoflurane preconditioning induced genomic changes in mouse cortex

BJA Open
Background: Altered patterns of genetic expression induced by isoflurane preconditioning in mouse brain have not yet been investigated. The aim of our pilot study is to examine the temporal sequence of changes in the transcriptome of mouse brain cortex ...
Umeshkumar Athiraman, Tusar Giri
doaj   +1 more source

Critical role of NLRP3-caspase-1 pathway in age-dependent isoflurane-induced microglial inflammatory response and cognitive impairment

Journal of Neuroinflammation, 2018
Background Elderly patients are more likely to suffer from postoperative cognitive dysfunction (POCD) after surgery and anesthesia. Except for declined organ function, the particular pathogenesis of POCD in elderly patients remains unknown. This study is
Zhi Wang, Shiyu Meng, Lin Cao, Ying Chen, Zhiyi Zuo, Shuling Peng   +5 more
doaj   +1 more source

In vivo field recordings effectively monitor the mouse cortex and hippocampus under isoflurane anesthesia

Neural Regeneration Research, 2016
Isoflurane is a widely used inhaled anesthetic in the clinical setting. However, the mechanism underlying its effect on consciousness is under discussion.
Yi-qing Yin, Li-fang Wang, Chao Chen, Teng Gao, Zi-fang Zhao, Cheng-hui Li   +5 more
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Isoflurane's Effect on Protein Conformation as a Proposed Mechanism for Preconditioning

Biochemistry Research International, 2011
Persistent alteration of protein conformation due to interaction with isoflurane may be a novel molecular aspect of preconditioning. We preincubated human serum albumin with isoflurane, dialyzed to release agent, and assessed protein conformation ...
Michelle R. Baker, Sean K. Benton, Christopher S. Theisen, Chad A. McClintick, Eugene E. Fibuch, Norbert W. Seidler   +5 more
doaj   +1 more source

Effects of inspired oxygen fractions in rabbits anesthetized with isoflurane or sevoflurane, maintained on spontaneous ventilation

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
It is important to identify the best inspired fraction of oxygen in a variety of situations, including sevoflurane or isoflurane anesthesia, in spontaneously breathing rabbits.
M. Horr, N. Nunes, E.G.F. Biteli, P.C.F. Lopes, A.P. Gering, J.V. Moro, F.D.L. Rocha   +6 more
doaj   +1 more source

Neuroprotective effects of dexmedetomidine against isoflurane-induced neuronal injury via glutamate regulation in neonatal rats

Drug Design, Development and Therapy, 2018
Xue Wang,1,2,* Yangyang Shan,1,* Zhiyin Tang,1 Linlin Gao,3 Hongtao Liu1 1Department of Anesthesiology, Shengjing Hospital, China Medical University, Shenyang 110004, China; 2Department of Anesthesiology, Xiangyang Central Hospital, Affiliated Hospital ...
Wang X, Shan Y, Tang Z, Gao L, Liu H
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