Results 31 to 40 of about 12,749 (205)
PLoS ONE, 2015 This study demonstrates that in mice subjected to hypoxia-ischemia (HI) brain injury isoflurane anesthesia initiated upon reperfusion limits a release of mitochondrial oxidative radicals by inhibiting a recovery of complex-I dependent mitochondrial ...
Sergey A Sosunov +5 more
doaj +1 more source
Isoflurane exposure during mid-adulthood attenuates age-related spatial memory impairment in APP/PS1 transgenic mice. [PDF]
PLoS ONE, 2012 Many in vitro findings suggest that isoflurane exposure might accelerate the process of Alzheimer Disease (AD); however, no behavioral evidence exists to support this theory.
Diansan Su +6 more
doaj +1 more source
Frontiers in Behavioral Neuroscience, 2020 Isoflurane contributes to cognitive deficits when used as a general anesthetic, and so does sleep deprivation (SD). Patients usually suffer from insomnia before an operation due to anxiety, fear, and other factors. It remains unclear whether preoperative
Kai Zhang +13 more
doaj +1 more source
Isoflurane Bilaterally Modulates Neuronal Excitability
, 2019 Volatile anesthetics induce hyperactivity during induction while producing anesthesia at higher con- centrations. They also bidirectionally modulate many neuronal functions. However, the neuronal mechanism is unclear.
Cheng Zhou (307152) +2 more
core +3 more sources
Anesthetic propofol attenuates the isoflurane-induced caspase-3 activation and Aβ oligomerization. [PDF]
PLoS ONE, 2011 Accumulation and deposition of β-amyloid protein (Aβ) are the hallmark features of Alzheimer's disease. The inhalation anesthetic isoflurane has been shown to induce caspase activation and increase Aβ accumulation.
Yiying Zhang +8 more
doaj +1 more source
BJA Open, 2022 Background: Emerging data suggest that volatile anaesthetic agents may be protective during critical illness. Methods: Three-month-old Sprague Dawley rats were randomly allocated to one of four groups: isoflurane during surgery followed by 3 days of ...
Keita Ikeda +2 more
doaj +1 more source
The effects of isoflurane anaesthesia on rats and mice
, 2021 The effects of isoflurane on the neurological system, cardiovascular system, respiratory system, digestive system, urinary system, endocrine system, reproductive system pregnancy and in paediatrics will be discussed in detail, including the consequences ...
Abegunde, Temitope
core
Preconditioning of isoflurane on spinal cord ischemia can increase the number of inducible nitric oxide synthase-expressing motor neurons in rat [PDF]
Korean Journal of Anesthesiology, 2010 BackgroundSpinal cord ischemia with resulting paraplegia remains one of the most common complications after repair of thoracoabdominal aortic aneurysms or dissection.
Yun-Hee Sung +6 more
doaj +1 more source
Isoflurane – Evaluation of a BAT value [PDF]
, 2023 The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area re-evaluated isoflurane [26675-46-7] and a maximum concentration at the workplace (MAK value) of 2 ml/m3 has been set for isoflurane.
Drexler, H +4 more
core +1 more source
Isoflurane-induced spatial memory impairment in mice is prevented by the acetylcholinesterase inhibitor donepezil. [PDF]
PLoS ONE, 2011 Although many studies have shown that isoflurane exposure impairs spatial memory in aged animals, there are no clinical treatments available to prevent this memory deficit.
Diansan Su +6 more
doaj +1 more source