Results 11 to 20 of about 218,062 (252)
Isoflurane aggravates pre-existing proteotoxicity in adult nematodes by suppressing mitochondrial fitness [PDF]
Scientific ReportsPost operative delirium (POD) is an acute complication, characterized by fluctuating attention and confusion, which may develop and persist into cognitive decline.
Tayir Elami +7 more
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British Journal of Anaesthesia, 1981 The introduction of isoflurane to clinical practice follows the search for a nonflammable, potent inhalation anesthetic which, above all, is chemically stable so as to resist biodegradation or attack by other chemicals. These attributes characterize isoflurane (Table 2).
J G, Wade, W C, Stevens
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Frontiers in Medicine, 2021 Objective: Surgery is the first line treatment of colorectal cancer (CRC). Anesthetic isoflurane may improve outcomes of cancer surgery. Herein, we investigated the effects of isoflurane on malignant behaviors of CRC cells and its underlying therapeutic ...
Zhe Cai, Liangyuan Suo, Zeqing Huang
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Paired assessment of volatile anesthetic concentrations with synaptic actions recorded in vitro. [PDF]
PLoS ONE, 2008 The volatile anesthetic isoflurane poses a number of experimental challenges in the laboratory. Due to its rapid evaporation, the open conditions of most in vitro electrophysiological recording systems make the determination of actual isoflurane ...
Stuart J McDougall +5 more
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Ferroptosis contributes to isoflurane-induced neurotoxicity and learning and memory impairment
Cell Death Discovery, 2021 Ferroptosis is a novel type of programmed cell death, which is different from apoptosis and autophagic cell death. Recently, ferroptosis has been indicated to contribute to the in vitro neurotoxicity induced by isoflurane, which is one of the most common
Pengfei Liu +5 more
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Stereoselectivity of isoflurane in adhesion molecule leukocyte function-associated antigen-1. [PDF]
PLoS ONE, 2014 Isoflurane in clinical use is a racemate of S- and R-isoflurane. Previous studies have demonstrated that the effects of S-isoflurane on relevant anesthetic targets might be modestly stronger (less than 2-fold) than R-isoflurane.
Weiming Bu +3 more
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Folia Histochemica et Cytobiologica, 2021 INTRODUCTION: Isoflurane anesthesia at the period of brain development can lead to neurotoxicity and long-term cognitive impairment. This study aimed to investigate the role of miR-497 on isoflurane-induced neurotoxicity.
Yuanyuan Que +5 more
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Anaesthesia, 1993 Summary A comparison of the analgesic efficacy of Entonox (50% nitrous oxide in oxygen) and Entonox with 0.2% isofturane was made in 18 consenting mothers during the first stage of labour. The inhalational gases were self‐administered during contractions over a 3 h study period using a standard Entonox demand valve and breathing ...
M Y, Wee, M A, Hasan, T A, Thomas
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Postanesthetic effects of isoflurane on behavioral phenotypes of adult male C57BL/6J mice. [PDF]
PLoS ONE, 2015 Isoflurane was previously the major clinical anesthetic agent but is now mainly used for veterinary anesthesia. Studies have reported widespread sites of action of isoflurane, suggesting a wide array of side effects besides sedation. In the present study,
Kumiko Yonezaki +6 more
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Biomedicines, 2022 The therapeutic effects of volatile anesthetics on mental diseases, particularly schizophrenia, have gained considerable interest. Although isoflurane is a commonly used volatile anesthetic, there’s no more evidence that it could work on treating ...
Hualing Peng +3 more
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