Results 21 to 30 of about 21,511 (293)

Low dose isoflurane exerts opposing effects on neuronal network excitability in neocortex and hippocampus. [PDF]

, 2012
The anesthetic excitement phase occurring during induction of anesthesia with volatile anesthetics is a well-known phenomenon in clinical practice. However, the physiological mechanisms underlying anesthetic-induced excitation are still unclear.
Dodt Hans-Ulrich, Hans-Ulrich Dodt, Eder, Matthias, Ranft, Andreas, Ludwig von Meyer, Zieglgänsberger Walter, Ranft Andreas, von Meyer, Ludwig, Klaus Becker, Eberhard Kochs, Becker, K., Walter Zieglgänsberger, Kochs Eberhard, Matthias Eder, Kochs, Eberhard, Becker Klaus, Andreas Ranft, von Meyer, L., Dodt, H., Dodt, H. U., Becker, Klaus, Zieglgänsberger, Walter, Eder, M., Eder Matthias, Zieglgänsberger, W., Meyer, Ludwig von, von Meyer Ludwig, Dodt, Hans-Ulrich, Ranft, A., Kochs, E.   +29 more
core   +1 more source

Isoflurane induces learning impairment that is mediated by interleukin 1β in rodents. [PDF]

PLoS ONE, 2012
Postoperative cognitive decline is a clinical syndrome. Volatile anesthetics are commonly used during surgery. It is conceivable that volatile anesthetics may contribute to postoperative cognitive decline.
Lin Cao, Liaoliao Li, Daowei Lin, Zhiyi Zuo   +3 more
doaj   +1 more source

Neuroprotective effects of miR-142-5p downregulation against isoflurane-induced neurological impairment

Diagnostic Pathology, 2020
Background Isoflurane can lead to neuron damage to the developing brain, resulting in learning and memory disability. The aim of this study was to investigate the role of miR-142-5p on isoflurane-induced neurological impairment.
Cuili Xie, Hongyue Wang, Yu Zhang, Yanhua Wei   +3 more
doaj   +1 more source

The effect of four anaesthetic protocols for maintenance of anaesthesia on trans-diaphragmatic pressure in dogs. [PDF]

PLoS ONE, 2013
The diaphragm is the main inspiratory muscle and the main indicator of diaphragmatic contractility is the trans-diaphragmatic pressure (Pdi). The aim of this clinical study was to determine the effect of four different anaesthetic protocols on Pdi in ...
Kiriaki Pavlidou, Ioannis Savvas, Yves P S Moens, Dimitrios Vasilakos, Dimitrios Raptopoulos   +4 more
doaj   +1 more source

Comparison of the effects of two anesthetics, isoflurane and urethane, on bladder function in rats

Journal of Pharmacological Sciences, 2023
We compared the effects of two anesthetics, isoflurane and urethane on bladder function in rats. Arterial pressure, cystometry (CMG), and rhythmic bladder contractions (RBCs) under isovolumetric conditions, mechanosensitive single-unit afferent ...
Naoki Aizawa, Tomoe Fujita
doaj   +1 more source

Isoflurane postconditioning reduces ischemia-induced nuclear factor-κB activation and interleukin 1β production to provide neuroprotection in rats and mice

Neurobiology of Disease, 2013
Application of isoflurane, a volatile anesthetic, after brain ischemia can reduce ischemic brain injury in rodents (isoflurane postconditioning). This study is designed to determine whether isoflurane postconditioning improves long-term neurological ...
Hong Li, Jinbo Yin, Liaoliao Li, Jiao Deng, Chenzhuo Feng, Zhiyi Zuo   +5 more
doaj   +1 more source

Isoflurane Bilaterally Modulates Neuronal Excitability

, 2019
Volatile anesthetics induce hyperactivity during induction while producing anesthesia at higher con- centrations. They also bidirectionally modulate many neuronal functions. However, the neuronal mechanism is unclear.
Ou, M (via Mendeley Data)
core   +3 more sources

The volatile anesthetic isoflurane increases endothelial adenosine generation via microparticle ecto-5'-nucleotidase (CD73) release.

PLoS ONE, 2014
Endothelial dysfunction is common in acute and chronic organ injury. Isoflurane is a widely used halogenated volatile anesthetic during the perioperative period and protects against endothelial cell death and inflammation.
Mihwa Kim, Ahrom Ham, Katelyn Yu-Mi Kim, Kevin M Brown, H Thomas Lee   +4 more
doaj   +1 more source

Isoflurane impairs oogenesis through germ cell apoptosis in C. elegans

Scientific Reports, 2021
Anesthetic isoflurane has been reported to induce toxicity. However, the effects of isoflurane on fecundity remain largely unknown. We established a system in C. elegans to investigate the effects of isoflurane on oogenesis.
Tao Zhang, Cheng Ni, Cheng Li, Pan Lu, Dan Chen, Yuanlin Dong, Johnathan R. Whetstine, Yiying Zhang, Zhongcong Xie   +8 more
doaj   +1 more source

Minocycline attenuates cognitive impairment induced by isoflurane anesthesia in aged rats. [PDF]

PLoS ONE, 2013
Postoperative cognitive dysfunction (POCD) is a clinical phenomenon characterized by cognitive deficits in patients after anesthesia and surgery, especially in geriatric surgical patients. Although it has been documented that isoflurane exposure impaired
Feijuan Kong, Shuping Chen, Yuan Cheng, Leilei Ma, Huishun Lu, Honghai Zhang, Wenwen Hu   +6 more
doaj   +1 more source