Results 21 to 30 of about 12,749 (205)

Neuroprotective effects of miR-142-5p downregulation against isoflurane-induced neurological impairment

open access: yesDiagnostic Pathology, 2020
Background Isoflurane can lead to neuron damage to the developing brain, resulting in learning and memory disability. The aim of this study was to investigate the role of miR-142-5p on isoflurane-induced neurological impairment.
Cuili Xie   +3 more
doaj   +1 more source

Isoflurane impairs oogenesis through germ cell apoptosis in C. elegans

open access: yesScientific Reports, 2021
Anesthetic isoflurane has been reported to induce toxicity. However, the effects of isoflurane on fecundity remain largely unknown. We established a system in C. elegans to investigate the effects of isoflurane on oogenesis.
Tao Zhang   +8 more
doaj   +1 more source

Effects of anesthesia on conventional and speckle tracking echocardiographic parameters in a mouse model of pressure overload [PDF]

open access: yes, 2015
Genetically‑modified mice are widely applied in cardiovascular studies as model organisms. Echocardiography is a key tool for evaluating cardiac and hemodynamic functions in mice.
Wu, Xiaofen   +7 more
core   +1 more source

Minocycline attenuates cognitive impairment induced by isoflurane anesthesia in aged rats. [PDF]

open access: yesPLoS ONE, 2013
Postoperative cognitive dysfunction (POCD) is a clinical phenomenon characterized by cognitive deficits in patients after anesthesia and surgery, especially in geriatric surgical patients. Although it has been documented that isoflurane exposure impaired
Feijuan Kong   +6 more
doaj   +1 more source

The effects of halothane and isoflurane on cardiovascular function in laterally recumbent horses [PDF]

open access: yes, 2005
Background. Experimental studies in adult horses have shown that general anaesthesia maintained with isoflurane is associated with less depression of cardiovascular function compared with halothane anaesthesia.
Henley, W   +5 more
core   +1 more source

Isoflurane postconditioning reduces ischemia-induced nuclear factor-κB activation and interleukin 1β production to provide neuroprotection in rats and mice

open access: yesNeurobiology of Disease, 2013
Application of isoflurane, a volatile anesthetic, after brain ischemia can reduce ischemic brain injury in rodents (isoflurane postconditioning). This study is designed to determine whether isoflurane postconditioning improves long-term neurological ...
Hong Li   +5 more
doaj   +1 more source

The effect of four anaesthetic protocols for maintenance of anaesthesia on trans-diaphragmatic pressure in dogs. [PDF]

open access: yesPLoS ONE, 2013
The diaphragm is the main inspiratory muscle and the main indicator of diaphragmatic contractility is the trans-diaphragmatic pressure (Pdi). The aim of this clinical study was to determine the effect of four different anaesthetic protocols on Pdi in ...
Kiriaki Pavlidou   +4 more
doaj   +1 more source

The volatile anesthetic isoflurane increases endothelial adenosine generation via microparticle ecto-5'-nucleotidase (CD73) release.

open access: yesPLoS ONE, 2014
Endothelial dysfunction is common in acute and chronic organ injury. Isoflurane is a widely used halogenated volatile anesthetic during the perioperative period and protects against endothelial cell death and inflammation.
Mihwa Kim   +4 more
doaj   +1 more source

Isoflurane anesthesia promotes cognitive impairment by inducing expression of β-amyloid protein-related factors in the hippocampus of aged rats. [PDF]

open access: yesPLoS ONE, 2017
Isoflurane anesthesia has been shown to be responsible for cognitive impairment in Alzheimer's disease (AD) and development of AD in the older age groups.
Shuai Zhang   +6 more
doaj   +1 more source

Janus Kinase Mediates Faster Recovery From Sevoflurane Anesthesia Than Isoflurane Anesthesia in the Migratory Locusts

open access: yesFrontiers in Physiology, 2022
Inhalation anesthetics isoflurane and sevoflurane have been widely used in clinical practice for anesthesia. However, the molecular mechanisms underlying the faster recovery from sevoflurane anesthesia than isoflurane anesthesia remain largely ...
Zongyuan Ma   +4 more
doaj   +1 more source

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