Results 31 to 40 of about 108,411 (239)
Comparison between sevoflurane and propofol on immunomodulation in an in vitro model of sepsis
IntroductionPatients with sepsis often require sedation and/or anesthesia. Although the immunomodulatory effects of anesthetics have been increasingly recognized, the molecular mechanisms require better elucidation. We compared the effects of sevoflurane
Tainá B. Oliveira+7 more
doaj +1 more source
Common anesthetic molecules prefer to partition in liquid disorder phase domain in a composite multicomponent membrane [PDF]
Despite a vast clinical application of anesthetics, the molecular level of understanding of general anesthesia is far from our reach. Using atomistic molecular dynamics simulation, we study the effects of common anesthetics: ethanol, chloroform and methanol in the fully hydrated symmetric multicomponent lipid bilayer membrane comprising of an ...
arxiv +1 more source
Sympathomimetic anesthetics [PDF]
The characteristic anaesthetic and other pharmacological properties of phencyclidine, ketamine, dexoxadrol and etoxadrol and the structure-activity relationship of these compounds have been described. Their possible mode of action is discussed in reference to the central depressant actions of the sympathomimetic amines.
openaire +3 more sources
Transport processes between aquaculture facilities activate the stress response in fish. To deal with these situations, the hypothalamic-pituitary-interrenal (HPI) axis releases cortisol, leading to an increase in circulating energy resources to restore ...
Ismael Jerez-Cepa+6 more
doaj +1 more source
Membrane Nanodomains Homeostasis During Propofol Anesthesia as Function of Dosage and Temperature [PDF]
Some anesthetics bind and potentiate gamma-aminobutyric-acid-type receptors, but no universal mechanism for general anesthesia is known. Furthermore, often encountered complications such as anesthesia induced amnesia are not understood. General anesthetics are hydrophobic molecules easily dissolving into lipid bilayers.
arxiv +1 more source
Performance of Marmoset Monkeys as Embryo Donors Is Reflected by Different Stress-Related Parameters
Non-human primates (NHPs) serve as embryo donors for embryo collection in order to mimic genetic diseases in humans by genetic modification. Reproductive health of the embryo donors is crucial, and chronic distress needs to be avoided.
Charis Drummer+5 more
doaj +1 more source
AS-IV enhances the antitumor effects of propofol in NSCLC cells by inhibiting autophagy
Non-small cell lung cancer (NSCLC) is one of the most lethal malignant tumors. It has been shown that the general anesthetic agents, propofol and astragaloside IV (AS-IV) both exert antitumor effects in NSCLC.
Liu Jintao+5 more
doaj +1 more source
Background: Propofol is a short-acting anesthetic, which is often used for induction and maintenance of general anesthesia, sedation for mechanically ventilated adults and procedural sedation.
Timo Längrich+6 more
doaj +1 more source
Anesthetics have been shown to alter tumor progression and seem to influence surgical cancer outcome. Circulating extracellular vesicles as mediators of intercellular communication are involved in cancer progression and may be influenced by anesthetics ...
Luisa Gluth+6 more
doaj +1 more source
Background and Aim: The postoperative shivering is one of the common complications of anesthesia, which can cause increased systemic blood pressure, oxygen consumption, intra optical pressure and heart rate in patients.
Maryam Kheirandish+3 more
doaj +2 more sources