ABSTRACT Background Oral leukoplakia (OL) is a potentially malignant disorder of the oral mucosa. Accurate prediction of malignant transformation (MT) remains a clinical challenge. This study aimed to develop and evaluate a machine learning model that integrates histopathological, demographic, and DNA content features to predict MT risk in OL.
Guilherme Iani Pontes +7 more
wiley +1 more source
Comparison of Preimplantation Genetic Diagnosis-Aneuploidy Screening (PGD-AS) With 5 Chromosome Versus 9/10 Chromosome Panels [PDF]
S. Sarajari +5 more
openalex +1 more source
The Evolving Landscape of CHD Genetics: A Contemporary Guide to Genetic Testing and Management
ABSTRACT Congenital heart disease (CHD) is the most common birth defect, affecting an estimated 9.4/1000 infants globally. The genetics of CHD is complex, with most cases thought to have multifactorial aetiology, implicating both genetic and environmental factors.
Bridget R. O'Malley +3 more
wiley +1 more source
EP09.03: Prenatal cf‐
D. M. Strah, Faris Mujezinović
openalex +1 more source
Comparative Analysis of the Tumour Mutational Burden in Erosive and Reticular Oral Lichen Planus
ABSTRACT Objective Oral lichen planus (OLP) is a chronic inflammatory disease classified as an oral potentially malignant lesion. The erosive and reticular forms of OLP have the potential for malignant transformation, with no consistent data indicating that one form is more likely to undergo malignant transformation than the other.
Priscila Laiza Rubim Leão +10 more
wiley +1 more source
The predictive value of anti-Müllerian hormone on embryo quality in PGT-A cycles analysis. [PDF]
Ni M +12 more
europepmc +1 more source
Cancer Hallmarks Expression in Oral Leukoplakia: Systematic Review and Meta‐Analysis
ABSTRACT Objectives To assess the available evidence on the expression of hallmarks of cancer and oral leukoplakia (OL) malignant transformation probability, with the goal of identifying the earliest oncogenic molecular events participating in oral cancer carcinogenesis.
I. González‐Ruiz +4 more
wiley +1 more source
UPR deficiency leads to poor growth, aneuploidy, and a trade-off between ER and general proteostasis in yeast. [PDF]
Bartolutti C +6 more
europepmc +1 more source
Susceptibility to Aneuploidy in Young Mothers of Down Syndrome Children [PDF]
Lucia Migliore +2 more
openalex +1 more source

