Results 181 to 190 of about 50,865 (308)

Phenotypic continuum and poor intracytoplasmic sperm injection intracytoplasmic sperm injection prognosis in patients harboring HENMT1 variants

Andrology, EarlyView.
Abstract Background Small RNAs interacting with PIWI (piRNAs) play a crucial role in regulating transposable elements and translation during spermatogenesis and are essential in male germ cell development. Disruptions in the piRNA pathway typically lead to severe spermatogenic defects and thus male infertility. The HENMT1 gene is a key player in piRNAs
Zeina Wehbe, Anne‐Laure Barbotin, Angèle Boursier, Caroline Cazin, Jean‐Pascal Hograindleur, Marie Bidart, Emeline Fontaine, Pauline Plouvier, Florence Puch, Véronique Satre, Christophe Arnoult, Selima Fourati Ben Mustapha, Raoudha Zouari, Nicolas Thierry‑Mieg, Pierre F. Ray, Zine‑Eddine Kherraf, Charles Coutton, Guillaume Martinez   +17 more
wiley   +1 more source

Preimplantation genetic testing for aneuploidy on previously cryopreserved unbiopsied blastocysts: a cohort study in women with IVF pregnancy loss. [PDF]

Reprod Biol Endocrinol
Cai H, Kirshenbaum M, Zhang D, Bai H, Li W, Xue X, Wang D, Wang X, Shi J.   +8 more
europepmc   +1 more source

Detection of aneuploidy in human spermatozoa using fluorescencein situ hybridization (FISH) [PDF]

, 1996
Hu He, Norio Miharu, Tomoya Mizunoe, Yoshiharu Nakaoka, Etsuji Okamoto, Koso Ohama   +5 more
openalex   +1 more source

Innovative all‐in‐one exome sequencing strategy for diagnostic genetic testing in male infertility: Validation and 10‐month experience

Andrology, EarlyView.
Abstract Background Current guidelines indicate that patients with extreme oligozoospermia or azoospermia should be tested for chromosomal imbalances, azoospermia factor (AZF) deletions and/or CFTR variants. For other sperm abnormalities, no genetic diagnostics are recommended.
Manon S. Oud, Nicole de Leeuw, Dominique F. C. M. Smeets, Liliana Ramos, Godfried W. van der Heijden, Raoul G. J. Timmermans, Maartje van de Vorst, Tom Hofste, Marlies J. E. Kempers, Marijn F. Stokman, Kathleen W. M. D'Hauwers, Brigitte H. W. Faas, Dineke Westra   +12 more
wiley   +1 more source

Aneuploidy confers a unique transcriptional and phenotypic profile to Candida albicans. [PDF]

Nat Commun
Mackey AI, Fillinger RJ, Hendricks PS, Thomson GJ, Cuomo CA, Bennett RJ, Anderson MZ.   +6 more
europepmc   +1 more source

Chromosome 1 aneusomy with 1p36 under‐representation is related to histologic grade, DNA aneuploidy, high c‐erb B‐2 and loss of bcl‐2 expression in ductal breast carcinoma [PDF]

, 1996
Fulvia Farabegoli, Claudio Ceccarelli, Donatella Santini, Davide Treré, Nicola Baldini, Mario Taffurelli, Massimo Derenzini   +6 more
openalex   +1 more source

Safety concerns of paternal drug exposure on fertility, pregnancy and offspring: An analysis based on the FDA adverse event reporting system

Andrology, EarlyView.
Abstract Background Growing evidence indicates that paternal condition significantly influences pregnancy outcomes and offspring health. However, assessing the safety of paternal drug exposure via randomized controlled trials poses ethical challenges, and relevant clinical studies consume a lot of resources to evaluate only a few drugs.
Yanbin Zeng, Wanlong Lin, Wei Zhuang
wiley   +1 more source

Aneuploidy of specific chromosomes is beneficial to cells lacking spindle checkpoint protein Bub3. [PDF]

PLoS Genet
Gadgil P, Ballew O, Sullivan TJ, Lacefield S.   +3 more
europepmc   +1 more source

Detection of aneuploidy for chromosomes 4, 6, 7, 8, 9, 10, 11, 12, 13, 17, 18, 21, X and Y by fluorescence in-situ hybridization in spermatozoa from nine patients with oligoasthenoteratozoospermia undergoing intracytoplasmic sperm injection [PDF]

, 1999
Myung‐Geol Pang
openalex   +1 more source

Role of intra‐individual variation in the detection of thresholds for DFI and for misclassification rates: A retrospective analysis of 14,775 SCSA® tests

Andrology, EarlyView.
Abstract Background Sperm DNA damage is associated with reduced male fertility after natural conception and intrauterine insemination. However, the impact on in vitro fertilization (IVF) and especially intracytoplasmic sperm injection (ICSI) treatments is still unclear.
Preben Christensen, Robert Fischer, Wolfgang Schulze, Vera Baukloh, Kimberly Kienast, Graham Coull, Erik T. Parner   +6 more
wiley   +1 more source