Results 181 to 190 of about 97,243 (292)

Development of a non-human primate sperm aneuploidy assay tested in the rhesus macaque (Macaca mulatta) [PDF]

, 2007
Lutz Froenicke, Pei-hsuan Hung, Catherine A. VandeVoort, Leslie A. Lyons   +3 more
openalex   +1 more source

Performance of Cell-Free DNA Screening for Fetal Common Aneuploidies and Sex Chromosomal Abnormalities: A Prospective Study from a Less Developed Autonomous Region in Mainland China [PDF]

, 2021
Yunli Lai, Xiaofan Zhu, Sheng He, Zirui Dong, Yanqing Tang, Fuben Xu, Yun Chen, Lintao Meng, Yuli Tao, Shang Yi, Jiasun Su, Hongqian Huang, Jingsi Luo, Tak Yeung Leung, Hongwei Wei   +14 more
openalex   +1 more source

Targeting ARPC1B+ Cancer Stem Cells to Sensitise Pancreatic Cancer to Gemcitabine Treatment

Cell Proliferation, EarlyView.
ARPC1B+ cancer stem cells (CSCs) in pancreatic cancer are identified as a subpopulation resistant to gemcitabine. In our study, drug repositioning, molecular docking, and surface plasmon resonance (SPR) technique jointly revealed that CK‐636 can directly target ARPC1B protein with high affinity. In vitro cytotoxicity, ex vivo organoid cultures, in vivo
Yang Wu, Jianpeng Zhang, Weixiong Zhu, Xinrui Zhu, Yi Liu, Xin Wang, Tianyu Zhao, Chun Zhang, Zili Zhang, Wenjie Shi, Run Shi, Zhaokai Zhou, Shaohui Xu   +12 more
wiley   +1 more source

Developmental arrest rate of an embryo cohort correlates with advancing reproductive age, but not with the aneuploidy rate of the resulting blastocysts in good prognosis patients: a study of 25,974 embryos. [PDF]

Aging (Albany NY)
Reig A, Seli E.
europepmc   +1 more source

Segmental aneuploidies in fetuses with isolated echogenic intracardiac focus among women younger than 35 years [PDF]

, 2020
Jing Wang, Lin Chen, Li Wang, Daishu Yin, Yang Zeng, Feng Tang, Yu Tian, Hongqian Liu   +7 more
openalex   +1 more source

Ovarian Aging: A Multifaceted Perspective on Mechanisms

Cell Proliferation, EarlyView.
A mechanistic network of ovarian aging, highlighting mitochondrial dysfunction as a central hub interconnected with genetic, metabolic, and inflammatory pathways.
Xiaoqing Zhang, Xinyi Dong, Xue Zhang, Suying Yuan, Qiran Zhang, Zilu Guo, Xiaoxue Yang, Qionghua Wang, Tianlan Yang, Donghui Huang   +9 more
wiley   +1 more source

Drivers of achiasmatic meiosis: sexual antagonism versus heteromorphy-dependent aneuploidy across sex-chromosome divergence. [PDF]

G3 (Bethesda)
Barboza A, Blackmon H.
europepmc   +1 more source

Human female meiosis revised: new insights into the mechanisms of chromosome segregation and aneuploidies from advanced genomics and time-lapse imaging [PDF]

, 2017
Antonio Capalbo, Eva R. Hoffmann, Danilo Cimadomo, Filippo Maria Ubaldi, Laura Rienzi   +4 more
openalex   +1 more source

Abnormal cleavage patterns in equine in vitro‐produced embryos lead to higher early pregnancy loss

Equine Veterinary Journal, EarlyView.
Summary Background Despite significant advances, in vitro production (IVP) of equine embryos continues to lack standardised embryo classification criteria and is associated with increased rates of early pregnancy loss compared with in vivo‐derived blastocysts.
Soledad Martin‐Pelaez, Alejandro de la Fuente, Kazuki Takahashi, Hugo Monteiro, Mauricio Mendes, Stuart Meyers, Pouya Dini   +6 more
wiley   +1 more source

Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models. [PDF]

Cancer Res Commun
Hu K, Liu CJ, Qin Z, Udager AM, Cieslik MP, Tomlins SA.   +5 more
europepmc   +1 more source