Results 181 to 190 of about 93,321 (331)

Multi‐Omics Reveal the Metabolic Changes in Cumulus Cells During Aging

open access: yesCell Proliferation, EarlyView.
Fatty acid β‐oxidation was elevated in cumulus cells from older mice. Tryptophan metabolism in aged cumulus cells was active. Supplementing with 5‐HT could mitigate aging damage in oocytes. ABSTRACT Maternal age has been reported to impair oocyte quality.
Liangyue Shi   +6 more
wiley   +1 more source

Revitalising Aging Oocytes: Echinacoside Restores Mitochondrial Function and Cellular Homeostasis Through Targeting GJA1/SIRT1 Pathway

open access: yesCell Proliferation, EarlyView.
ECH protects senescent oocytes by stabilising the cytoskeleton, restoring mitochondrial function, reducing oxidative stress and maintaining cellular homeostasis, primarily through the GJA1/SIRT1 signalling pathway. ABSTRACT As maternal age increases, the decline in oocyte quality emerges as a critical factor contributing to reduced reproductive ...
Liuqing Yang   +13 more
wiley   +1 more source

Aneuploidy in yeast. [PDF]

open access: bronze, 1960
B. S. Cox
openalex  

GANT61 Modulates Autophagy and Lipid Metabolism in Ovarian Cancer

open access: yesCell Proliferation, EarlyView.
GANT61 induced autophagy via the AKT pathway and promoted the accumulation of lipid droplets in both cell lines. The molecular mechanism behind this lipid accumulation appears to involve the mediation of SREBP1. Furthermore, the combination of GANT61 with CQ/Fatostatin significantly inhibited the proliferation and clonogenicity of SKOV3 and SKOV3PTX ...
Yibin Pan   +13 more
wiley   +1 more source

Clinical and biological significance of aneuploidy in human tumours.

open access: green, 1984
Michael Friedlander   +2 more
openalex   +1 more source

Detection of aneuploidy in human spermatozoa using fluorescencein situ hybridization (FISH) [PDF]

open access: bronze, 1996
Hu He   +5 more
openalex   +1 more source

Whole‐Genome Sequencing and Phenotyping Reveal Specific Adaptations of Lachancea thermotolerans to the Winemaking Environment

open access: yesMolecular Ecology, EarlyView.
ABSTRACT Adaptation to the environment plays an essential role in yeast evolution as a consequence of selective pressures. Lachancea thermotolerans, a yeast related to fermentation and one of the current trends in wine technology research, has undergone an anthropisation process, leading to a notable genomic and phenomic differentiation.
Javier Vicente   +5 more
wiley   +1 more source

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