P-168. Analysis of aneuploidy in unfertilized ICSI oocytes with two rounds of triple FISH [PDF]
Elena Martini+4 more
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USP33 Regulates DNA Damage Response and Carcinogenesis Through Deubiquitylating and Stabilising p53
Our findings demonstrated that USP33 deubiquitinates p53 and regulates its stability, and moreover, DNA damage can stabilise p53 through enhancing its association with USP33, leading to strong DNA damage response (DDR). However, USP33 deficiency results in defective DDR, facilitating DEN‐induced hepatocarcinogenesis in hepatocyte‐specific USP33 KO mice.
Yuqi Zhu+8 more
wiley +1 more source
AR alterations inform circulating tumor DNA detection in metastatic castration resistant prostate cancer patients. [PDF]
Knutson TP+15 more
europepmc +1 more source
Rapid determination of zygosity and common aneuploidies from amniotic fluid cells using quantitative fluorescent polymerase chain reaction following genetic amniocentesis in multiple pregnancies [PDF]
C.-P. Chen
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hESCsdel18q exhibit delayed and impaired anterior neuroectoderm induction, leading to deficient RPE specification. hESCsdel18q lines showed dysregulation of TGFβ signalling, and endogenous overactivation of activin/nodal/TGFβ in hESCsdel18q leads to improper anterior/posterior neuroectodermal fate commitments.
Yingnan Lei+9 more
wiley +1 more source
Perinatal Outcomes and Management of Umbilical Vein Varix: A Comprehensive Review of 392 Cases. [PDF]
Ghahremani T+5 more
europepmc +1 more source
Assessment of sex chromosome aneuploidy in sperm nuclei from 47,XXY and 46,XY/47,XXY males: comparison with fertile and infertile males with normal karyotype [PDF]
Nathalie Rives
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Multi‐Omics Reveal the Metabolic Changes in Cumulus Cells During Aging
Fatty acid β‐oxidation was elevated in cumulus cells from older mice. Tryptophan metabolism in aged cumulus cells was active. Supplementing with 5‐HT could mitigate aging damage in oocytes. ABSTRACT Maternal age has been reported to impair oocyte quality.
Liangyue Shi+6 more
wiley +1 more source
APCAD Part 2: A Novel Method for Detection of Meiotic Aneuploidy in Preimplantation Embryos. [PDF]
Verdyck P+5 more
europepmc +1 more source
Mechanisms involved in the induction of aneuploidy: the significance of chromosome loss [PDF]
Analía Seoane+2 more
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