Results 221 to 230 of about 95,739 (341)

Ubiquitination dynamics in human tumour viruses: Viral infection, oncogenesis and antiviral therapy

The FEBS Journal, EarlyView.
The ubiquitin system is essential for cellular homeostasis and regulates many processes. Viruses, including oncogenic ones, exploit or evade this system to survive and replicate. This review explores how human tumour viruses manipulate the ubiquitination system to complete their life cycle, evade immunity and promote cancer.
Oscar Trejo‐Cerro, Martina Bergant Marušič, Justyna Broniarczyk   +2 more
wiley   +1 more source

Detection of human brain cancers using genomic and immune cell characterization of cerebrospinal fluid through CSF-BAM. [PDF]

Cancer Discov
Pearlman AH, Wang Y, Kalluri A, Parker M, Cohen JD, Dudley J, Rincon-Torroella J, Xia Y, Gensler R, Alfonzo Horowitz M, Theodore JN, Dobbyn L, Popoli M, Ptak J, Silliman N, Judge K, Calabresi PA, Groves M, Jackson CM, Jackson EM, Jallo GI, Lim M, Luciano M, Mukherjee D, Naidoo J, Rozati S, Sterling CH, Weingart J, Koschmann C, Mansouri A, Glantz M, Kamson D, Schreck KC, Pardo CA, Holdhoff M, Konig MF, Paul S, Kinzler KW, Papadopoulos N, Vogelstein B, Douville C, Bettegowda C.   +41 more
europepmc   +1 more source

DNA aneuploidy and cell proliferation in relation to histology and prognosis in patients with Hodgkin's disease

, 1993
Frans Erdkamp, W.P.M. Breed, Harry C. Schouten, Willy C. M. Janssen, Johannes J.M.L. Hoffmann, JT Wijnen, G.H. Blijham   +6 more
openalex   +1 more source

Detection of aneuploidy in human spermatozoa using fluorescencein situ hybridization (FISH) [PDF]

, 1996
Hu He, Norio Miharu, Tomoya Mizunoe, Yoshiharu Nakaoka, Etsuji Okamoto, Koso Ohama   +5 more
openalex   +1 more source

Lysine demethylase 4A is a centrosome‐associated protein required for centrosome integrity and genomic stability

The FEBS Journal, EarlyView.
KDM4A, a chromatin eraser, localizes to the centrosomes. Its demethylase activity is essential for maintaining centrosome number and integrity, independent of gene expression changes. Loss of KDM4A leads to centrosome amplification, pseudo‐bipolar spindle formation, and chromosome segregation errors, including micronuclei and chromatin bridges.
Pratim Chowdhury, Xiaoli Wang, Richard I. Han, Manga Motrapu, Ashley G. Boice, Yuya Nakatani, Sofia Vargas‐Hernandez, Julia F. Love, Claude Chew, Sandra L. Grimm, Dereck Mezquita, Frank M. Mason, Elisabeth D. Martinez, Cristian Coarfa, Cheryl L. Walker, Anna‐Karin Gustavsson, Ruhee Dere   +16 more
wiley   +1 more source

Clinical experience of genome-wide non-invasive prenatal testing as a first-tier screening test in a cohort of 59,771 pregnancies. [PDF]

PLoS One
Zhen J, Zhang L, Wang H, Chen X, Wang W, Li L, Zhang Q.   +6 more
europepmc   +1 more source

Assessment and classification of sex cord‐stromal tumours of the testis: recommendations from the testicular sex cord‐stromal tumour (TESST) group, an Expert Panel of the Genitourinary Pathology Society (GUPS) and International Society of Urological Pathology (ISUP)

Histopathology, EarlyView.
FH immunohistochemistry is recommended in clinically malignant Leydig cell tumours and in primary Leydig cell tumours with aggressive histopathologic features. Aims Testicular sex cord‐stromal tumours (TSCSTs) are relatively rare, accounting for ~5% of all testicular neoplasms.
Andres M Acosta, Maurizio Colecchia, Eva Comperat, Kristine M Cornejo, Anthony J Gill, Sounak Gupta, John C Cheville, Muhammad T Idrees, Chia‐Sui Kao, Fiona Maclean, Andres Matoso, Maria Rosaria Raspollini, Kvetoslava Michalova, Miguel Reyes Mugica, Satish K Tickoo, Toyonori Tsuzuki, Thomas M Ulbright, Sean R Williamson, Stephanie Siegmund, Lynette M Sholl, Pilar Gonzalez‐Peramato, Daniel M Berney   +21 more
wiley   +1 more source

P-168. Analysis of aneuploidy in unfertilized ICSI oocytes with two rounds of triple FISH [PDF]

, 1997
Elena Martini, S.P. Flaherty, Nicholas J. Swann, D. Payne, C.D. Matthews   +4 more
openalex   +1 more source

Investigation of the Telomere Length in PERI‐Implant Oral Mucosa Cells

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background The biological effects of dental implants on peri‐implant tissues have been widely investigated. Recent reports of oral squamous cell carcinoma (OSCC) cases adjacent to dental implants have raised concerns regarding the potential impact of implant materials on cellular aging and oncogenic transformation.
Fernando Costa Giffoni, Thaís Ellen Chaves Gomes, Priscila Nazaré de Souza, Paula Valente e Silva, Luiz Alexandre Viana Magno, Amanda Lage Cândido, Marcelo Faria Lasmar, Sebastião Guilherme de Oliveira Neto, Marcus Vinicius Lucas Ferreira, Thiago Moreira Gonçalves Araujo, Luara Isabela dos Santos, Bruno Ramos Chrcanovic, Ricardo Santiago Gomez, Roberta Rayra Martins‐Chaves   +13 more
wiley   +1 more source

Global modulation of gene expression and transcriptome size in aneuploid combinations of maize. [PDF]

Proc Natl Acad Sci U S A
Yang H, Brennan V, Gao Z, Liu J, Boadu F, Cheng J, Birchler JA.   +6 more
europepmc   +1 more source