Results 71 to 80 of about 95,739 (341)
術中フローサイトメトリーを用いた頭蓋内悪性リンパ腫と膠芽腫の鑑別 [PDF]
, 2019 博士(医学) 甲第697号(主論文の要旨、要約、審査結果の要旨、本文)，著者名:Shunichi KORIYAMA・Masayuki NITTA・Takahiro SHIOYAMA・Takashi KOMORI・Takashi MARUYAMA・Takakazu KAWAMATA・Yoshihiro MURAGAKI，タイトル:Intraoperative Flow Cytometry Enables the Differentiation of Primary Central Nervous ...
郡山 峻一
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Advanced Science, EarlyView.Simulated microgravity induces distinct mitochondrial hyperactivation patterns‐elevated OXPHOS and MMP‐which accelerate meiosis without SAC failure but delays MTOC coalescence, leading to spindle defects and meiotic arrest. Prolonging M‐phase restores MTOC assembly and oocyte maturation.
Lei Ge +7 more
wiley +1 more source
Adaptation to high ethanol reveals complex evolutionary pathways [PDF]
, 2015 Tolerance to high levels of ethanol is an ecologically and industrially relevant phenotype of microbes, but the molecular mechanisms underlying this complex trait remain largely unknown.
Arslan, Ahmed +15 more
core +8 more sources
Sequencing the Major Mycosphaerella Pathogens of Wheat and Banana [PDF]
, 2009 Mycosphaerella is one of the largest genera of plant-pathogenic fungi with more than 1,000 named species, many of which are important pathogens causing leaf spotting diseases in a wide variety of crops including cereals, citrus, banana, eucalypts, soft ...
Kema, G.H.J.
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World Journal of Stem Cells, 2016 Stem cells hold enormous promise for regenerative medicine as well as for engineering of model systems to study diseases and develop new drugs. The discovery of protocols that allow for generating induced pluripotent stem cells (IPSCs) from somatic cells has brought this promise steps closer to reality.
Jorge Garcia-Martinez +4 more
openaire +3 more sources
Advanced Science, EarlyView.Meiosis is a specialized form of cell division that has different regulation and mechanisms with mitosis in numerous aspects. Particularly, meiosis I is unique and occurs only in germ cells to separate homologous chromosomes. Thus, determining how this unusual chromosome segregation behavior is established is central to understanding germ cell ...
Yu Li, Zihao Zhang, Yu Zhang, Bo Xiong
wiley +1 more source
Serine-Dependent Sphingolipid Synthesis Is a Metabolic Liability of Aneuploid Cells
Cell Reports, 2017 Aneuploidy disrupts cellular homeostasis. However, the molecular mechanisms underlying the physiological responses and adaptation to aneuploidy are not well understood.
Sunyoung Hwang +10 more
doaj +1 more source
Nuclear tau and its potential role in Alzheimer’s disease [PDF]
, 2016 Tau protein, found in both neuronal and non-neuronal cells, forms aggregates in neurons that constitutes one of the hallmarks of Alzheimer’s disease (AD).
Al-Hilaly, Youssra +2 more
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Transcriptional consequences of aneuploidy [PDF]
Proceedings of the National Academy of Sciences, 2012 Aneuploidy, or an aberrant karyotype, results in developmental disabilities and has been implicated in tumorigenesis. However, the causes of aneuploidy-induced phenotypes and the consequences of aneuploidy on cell physiology remain poorly understood.
Sheltzer, Jason Meyer +3 more
openaire +4 more sources
Benchmarking Ploidy Estimation Methods for Bulk and Single‐Cell Whole Genome Sequencing
Advanced Science, EarlyView.It comprehensively benchmarks computational tools for ploidy estimation from bulk and single‐cell whole‐genome sequencing data. The results highlight the strengths and limitations of each method under different conditions and identify PURPLE and SeCNV show top performance in bulk and single‐cell settings, respectively.
Yawei Song +8 more
wiley +1 more source