Results 81 to 90 of about 47,394 (257)

Toxic Effects of Bisphenol A and Its Analogs on Ovarian Structure and Function: A Narrative Review of Ovary‐Focused Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) is a widely used industrial chemical found in polycarbonate plastics and epoxy resins and is recognized for its endocrine‐disrupting properties. Human exposure is common due to its presence in food packaging and everyday products. As BPA use has been restricted, structurally similar compounds such as BPS, BPB, BPAF, and BADGE
Nurbanu Zengin, Marwa Tawfıq Ahmed Alsalım, Muhammed Canik, Sevda Bağdatlı, Nazan Deniz Yön   +4 more
wiley   +1 more source

Application of Cell‐Free DNA Barcode‐Enabled Single‐Molecule Test for Non‐Invasive Prenatal Testing of α‐Thalassemia and β‐Thalassemia

Journal of Clinical Laboratory Analysis, EarlyView.
We evaluated the cfBEST assay for non‐invasive prenatal testing of α‐ and β‐thalassemia in 72 families. The assay correctly identified 88 of 93 fetal alleles, achieving an overall accuracy of 94.6%, a sensitivity of 94%, and a specificity of 95.35%, with 100% concordance with postnatal follow‐up.
Qin Liu, Na Ma, Wanglan Tang, Qianting Chen, Deguo Tang, Chunyan Zeng, Xiaofeng Wang, Hui Xi   +7 more
wiley   +1 more source

Non-random Mis-segregation of Human Chromosomes

Cell Reports, 2018
Summary: A common assumption is that human chromosomes carry equal chances of mis-segregation during compromised cell division. Human chromosomes vary in multiple parameters that might generate bias, but technological limitations have precluded a ...
Joseph Thomas Worrall, Naoka Tamura, Alice Mazzagatti, Nadeem Shaikh, Tineke van Lingen, Bjorn Bakker, Diana Carolina Johanna Spierings, Elina Vladimirou, Floris Foijer, Sarah Elizabeth McClelland   +9 more
doaj   +1 more source

Detection and Clinical Significance of Chromosomal Mosaicism in Prenatal Diagnosis: A Retrospective Study From a Prenatal Diagnosis Center

Journal of Clinical Laboratory Analysis, EarlyView.
This retrospective study of 79 prenatal mosaicism cases found that noninvasive prenatal testing (NIPT) had significantly higher sensitivity (90.74%) than first‐ and second‐trimester serum screening, while chromosomal microarray analysis (CMA) showed better concordance with karyotyping (90.00%) than QF‐PCR (58.21%).
Yuanyuan Pei, Xiaojin Luo, Jian Ran, Liang Hu, Weiqiang Liu, Fengxiang Wei   +5 more
wiley   +1 more source

aneuploidy

Citation: 'aneuploidy' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10394 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +2 more sources

Current Evidence for Circulating Tumor DNA in Sarcoma: Challenges and Opportunities for Clinical Application

Journal of Surgical Oncology, EarlyView.
ABSTRACT Sarcomas represent a diverse group of mesenchymal tumors with high rates of recurrence after resection. While recent technical advances have enabled the detection of rare circulating tumor DNA (ctDNA) in other malignancies, the complexity and heterogeneity of sarcoma genomics have historically limited ctDNA in these cancers.
Kristin E. Goodsell, Jason A. Carter, Hannah R. Abrams, Harveshp Mogal, Elizabeth T. Loggers, Jeremy Sharib   +5 more
wiley   +1 more source

Fetal Heart Rate at 12 Weeks' Gestation and the Risk of Preterm Birth

Journal of Ultrasound in Medicine, EarlyView.
Objectives To prospectively validate the association between fetal heart rate (FHR) at the 12‐week scan and the risk of preterm birth (PTB), including spontaneous preterm birth (sPTB). Methods This prospective cohort study included 1276 singleton pregnancies undergoing routine first‐trimester screening at 11–13 + 6 weeks' gestation and followed until ...
José Morales‐Roselló, Alicia Soriano‐Payá, Blanca Novillo‐Del Álamo, Alicia Martínez‐Varea   +3 more
wiley   +1 more source

Feasibility and Reproducibility of a Structure‐Guided Deep Learning Model for Automatic Detection of the Standard Sagittal Plane in First‐Trimester Nuchal Translucency Assessment Using 3D Ultrasound

Journal of Ultrasound in Medicine, EarlyView.
Objectives Accurate nuchal translucency (NT) measurement for assessing the risk of fetal genetic abnormalities requires precise acquisition of the mid‐sagittal plane (MSP). However, achieving an appropriate MSP is technically challenging due to anatomical variability and operator dependence inherent in conventional 2‐dimensional (2D) ultrasound.
Hayan Kwon, Hyewon Hur, Hyun Cheol Cho, Yun ji Jung, Suhra Kim, Ja‐Young Kwon   +5 more
wiley   +1 more source

Selection forces underlying aneuploidy patterns in cancer

Molecular & Cellular Oncology
Aneuploidy, the presence of an aberrant number of chromosomes, has been associated with tumorigenesis for over a century. More recently, advances in karyotyping techniques have revealed its high prevalence in cancer: About 90% of solid tumors and 50–70 ...
Tamara C. Klockner, Christopher S. Campbell   +1 more
doaj   +1 more source

Differences between mitotically old and young endometrial tumors

The Journal of Pathology, EarlyView.
Abstract Human tumors likely differ in their mitotic ages, reflecting how many divisions elapse between the final tumor progenitor cell and surgical removal. We used a rapidly fluctuating CpG (fCpG) methylation clock to infer relative endometrial adenocarcinomas (EAC) mitotic ages.
Kellie Kim, Darryl Shibata
wiley   +1 more source