Results 131 to 140 of about 586,820 (418)

Elucidating the Molecular Landscape of Cystic Kidney Disease: Old Friends, New Friends and Some Surprises

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cystic kidney diseases (CyKD) are a diverse group of disorders affecting more than 1 in 1000 individuals. Over 120 genes are implicated, primarily encoding components of the primary cilium, transcription factors, and morphogens. Prognosis varies greatly by molecular diagnosis. Causal variants are not identified in 10%–60% of individuals due to
Deborah Watson, Frank Mentch, Jonathan Billings, Kayleigh Ostberg, Michael E. March, Jennifer M. Kalish, Dong Li, India Cannon, Lisa M. Guay‐Woodford, Erum Hartung, Alanna Strong   +10 more
wiley   +1 more source

Interpretation of an aneurysm: [PDF]

European Heart Journal, 2015
A 51-year-old female was referred to our institution for an accidentally found sinus of valsalva aneurysm (SVA). Multi-slice computer tomography and cardiovascular magnetic resonance imaging (CMR) well depicted a 76 × 43 mm right SVA sprawling over right ventricular outflow tract ( Panel A ).
Yongshi Wang, Michael Markl, Boting Wu, Xianhong Shu   +3 more
openaire   +3 more sources

Global Aortic Pulse Wave Velocity is Unchanged in Bicuspid Aortopathy With Normal Valve Function but Elevated in Patients With Aortic Valve Stenosis: Insights From a 4D Flow MRI Study of 597 Subjects

Journal of Magnetic Resonance Imaging, Volume 57, Issue 1, Page 126-136, January 2023., 2023
Background Aortopathy is common with bicuspid aortic valve (BAV), and underlying intrinsic tissue abnormalities are believed causative. Valve‐mediated hemodynamics are altered in BAV and may contribute to aortopathy and its progression. The contribution of intrinsic tissue defects versus altered hemodynamics to aortopathy progression is not known ...
Ethan M.I. Johnson, Michael B. Scott, Kelly Jarvis, Bradley Allen, James Carr, S. Christopher Malaisrie, Patrick McCarthy, Christopher Mehta, Paul W.M. Fedak, Alex J. Barker, Michael Markl   +10 more
wiley   +1 more source

Analysis of AneuRisk65 data: warped logistic discrimination [PDF]

arXiv, 2013
We analyze the AneuRisk65 curvature functions using a likelihood-based warping method for sparsely sampled curves, and combine it with logistic regression in order to discriminate subjects with aneurysms at or after the terminal bifurcation of the internal carotid artery (the most life-threatening) from subjects with no aneurysms or aneurysms along the
arxiv  

Single-center experience in the treatment of visceral artery aneurysms [PDF]

, 2019
Background: Visceral artery aneurysms (VAAs), although rare, represent a life-threatening disease with high mortality rates. With the more frequent use of diagnostic tests, there has been an incidental detection of these lesions which are mostly ...
Di Girolamo, A., Gattuso, R., Giglio, A., Gossetti, B., Irace, L., Martinelli, O.   +5 more
core   +1 more source

Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation for Diffuse Cutaneous Systemic Sclerosis: Identifying Disease Risk Factors for Toxicity and Long‐Term Outcomes in a Prospective, Single‐Arm Trial

Arthritis &Rheumatology, EarlyView.
Objective Two randomized trials for patients with diffuse systemic sclerosis (SSc) demonstrated an overall survival (OS) and event‐free survival (EFS) advantage of autologous hematopoietic stem cell transplantation (AHSCT) using CD34+ selected peripheral blood stem cells (PBSCs) compared with monthly cyclophosphamide (CY).
George E. Georges, Dinesh Khanna, Mark H. Wener, Matthew G. Mei, Maureen D. Mayes, Robert W. Simms, Vaishali Sanchorawala, Chitra Hosing, Suzanne Kafaja, Attaphol Pawarode, Leona A. Holmberg, Jason Kolfenbach, Daniel E. Furst, Keith M. Sullivan, Suiyuan Huang, Ted Gooley, Richard A. Nash   +16 more
wiley   +1 more source

IMPACT (Information Medically Pertinent in Acute Computed Tomography) requests: Delphi study to develop criteria standards for adequate clinical information in computed tomography requests in the Australian emergency department

Journal of Medical Radiation Sciences, Volume 69, Issue 4, Page 421-430, December 2022., 2022
Currently, in Australia there are no published guidelines on what constitutes adequate clinical information in requests for Computed Tomography (CT). An e‐Delphi study was conducted to gain consensus from CT reporting consultant radiologists as to what constitutes adequate clinical information for patients presenting to the emergency department with ...
Chelsea Castillo, Tom Steffens, Georgia Livesay, Lawrence Sim, Liam Caffery   +4 more
wiley   +1 more source

Tratamento endovascular de pseudoaneurisma de aorta torácica com fístula aorto-brônquica em pós-operatório tardio de cirurgia de correção de coarctação de aorta Endovascular treatment of thoracic aortic pseudoaneurysm with aortobronchial fistula in the late postoperative period of surgical correction of the aortic coarctation

Jornal Vascular Brasileiro, 2011
Fístula aorto-brônquica é uma conexão entre a aorta e o brônquio, e mesmo quando imediatamente reconhecida e tratada possui alto risco de letalidade. Pode se desenvolver após cirurgias de aorta, e é geralmente uma consequência de pseudoaneurisma.
Ana Augusta Gayoso Neves, Alexandre Gayoso Neves Maia de Oliveira, Roberto Teodoro Beck, Ricardo Virginio dos Santos, Francisco Carlos Padilha Moreira, Alexandre Campos Moraes Amato   +5 more
doaj   +1 more source

Modelling the evolution of cerebral aneurysms: biomechanics, mechanobiology and multiscale modelling [PDF]

, 2014
Intracranial aneurysms (IAs) are abnormal dilatations of the cerebral vasculature. Computational modelling may shed light on the aetiology of the disease and lead to improved criteria to assist diagnostic decisions.
Selimovic, Alisa, Ventikos, Yiannis, Watton, Paul N.   +2 more
core   +1 more source

Atherosclerotic Plaque Progression and Incident Cardiovascular Events in a 10‐Year Prospective Study of Patients With Systemic Lupus Erythematosus: The Impact of Persistent Cardiovascular Risk Factor Target Attainment and Sustained DORIS Remission

Arthritis &Rheumatology, EarlyView.
Objective Cardiovascular disease (CVD) is a leading cause of death in individuals with systemic lupus erythematosus (SLE). We assessed atherosclerotic plaque progression and incident cardiovascular events in patients with SLE over a 10‐year follow‐up.
Nikolaos Papazoglou, Petros P. Sfikakis, Maria G. Tektonidou   +2 more
wiley   +1 more source