Results 41 to 50 of about 261,967 (310)

Ventral Midline Hysterectomy, Ovariectomy, and Ovariohysterectomy in Mus Musculus: A Surgical Protocol

Scientific Reports
Mice (Mus musculus) are one of the most commonly used animal species in basic science and translational research worldwide. Ovariectomy and hysterectomy are frequently employed to explore the systemic effects of the sex-hormone axis and other ...
Peyton L. Nisson, Takuma Maeda, Hiroki Uchikawa, Oscar Cisneros, Michael T. Lawton, Tomoki Hashimoto   +5 more
doaj   +1 more source

Short- and Long-Term Effects of Rehabilitation after Perimesencephalic Subarachnoid Hemorrhage

Diseases, 2021
In about 25% of patients with spontaneous subarachnoid hemorrhage (SAH), a bleeding source cannot be identified during radiological diagnostics. Generally, the outcome of perimesencephalic or prepontine (PM) SAH is known to be significantly better than ...
Jens Schmitz, Sepide Kashefiolasl, Nina Brawanski, Nazife Dinc, Florian Gessler, Christian Senft, Stephanie Tritt, Volker Seifert, Jürgen Konczalla   +8 more
doaj   +1 more source

The ETTAA study protocol: a UK-wide observational study of 'Effective Treatments for Thoracic Aortic Aneurysm'. [PDF]

, 2015
Introduction Chronic thoracic aortic aneurysm (CTAA) affecting the arch or descending aorta is an indolent but life-threatening condition with a rising prevalence as the UK population ages.
Catarino, P., ETTAA Collaborators, Gray, J, Vallabhaneni, S, Vale, L., Vallabhaneni, Srinivasa, Cook, A., Moorjani, N, Moorjani, Narain, Vale, Luke, Sharples, L., Gray, Joanne, Cook, Andrew, Elefteriades, JA, Sastry, P., Sharples, Linda, Vallabhaneni, S. R., Sastry, P, Moorjani, N., Hughes, V., Elefteriades, John, Cook, A, Catarino, Pedro, Hughes, V, Elefteriades, J., Hayes, P, on behalf of the ETTAA collaborators, Thompson, M., Hayes, P., Gray, J., Vale, L, Large, Stephen, Catarino, P, Thompson, Matt, Sharples, L, Hughes, Victoria, Elefteriades, John A, Hayes, Paul, Thompson, M, Sastry, Priya, Large, Stephen R, Large, SR, Large, S. R.   +42 more
core   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

High-resolution magnetic resonance imaging of intracranial aneurysms treated by flow diversion

Interdisciplinary Neurosurgery, 2017
Object: Flow diverter treatment of intracerebral aneurysms is highly successful and has low rates of morbidity and mortality. Among the primary concerns after endovascular treatment are failure to achieve aneurysm obliteration and recurrence, and close ...
Jian Guan, MD, Michael Karsy, MD, PhD, Scott McNally, MD, PhD, Adam de Havenon, MD, M. Yashar S. Kalani, MD, PhD, Philipp Taussky, MD, Seong-Eun Kim, PhD, Min S. Park, MD   +7 more
doaj   +1 more source

Treatment of arterial aneurysms of anterior cerebral circulation [PDF]

Vojnosanitetski Pregled, 2002
Objectives: To analyze the outcome of either surgical or conservative treatment of patients with aneurysms on cerebral arteries. Design Retrospective study on 114 patients (89 operated and 25 not operated). Methods: Clinical state was graded from 0 to V,
Roganović Zoran, Pavlićević Goran, Tadić Radenko   +2 more
doaj   +1 more source

TGFβ signaling pathways in human health and disease

Frontiers in Molecular Biosciences, 2023
Transforming growth factor beta (TGFβ) is named for the function it was originally discovered to perform-transformation of normal cells into aggressively growing malignant cells. It became apparent after more than 30 years of research, however, that TGFβ
Pei-Yu Chen, Lingfeng Qin, Michael Simons, Michael Simons   +3 more
doaj   +1 more source

Stent treatment for huge aneurysm of the common hepatic artery: A case report [PDF]

, 2019
Objective/Background: Huge aneurysm of the visceral artery is rare and a treatment strategy for such cases has not yet been established. Here, we report a case of huge aneurysm of the common hepatic artery (44-mm diameter) successfully treated by stent ...
Adachi, Tomohiko, Yasuhiro Maruya, MD, PhD, Takatsuki, Mitsuhisa, Tomohiko Adachi, MD, PhD, Maruya, Yasuhiro, Baimakhanov, Zhassulan, Masaaki Hidaka, MD, PhD, Mitsuhisa Takatsuki, MD, PhD, Manat Zhakubayev, MD, Hidaka, Masaaki, Zhassulan Baimakhanov, MD, PhD, Susumu Eguchi, MD, PhD, Soyama, Akihiko, Sakomoto, Ichiro, Ichiro Sakomoto, MD, PhD, Eguchi, Susumu, Akihiko Soyama, MD, PhD, Zhakubayev, Manat   +17 more
core   +1 more source

Rheumatoid Arthritis, Frailty, and Outcomes of Surgical Hospitalizations: A National Population‐Based Analysis

Arthritis Care &Research, EarlyView.
Objective Hospitalization, particularly for surgery, represents a period of heightened stress. We evaluated how frailty attenuates the association of rheumatoid arthritis (RA) with negative health outcomes after elective noncardiac surgery. Methods We conducted a cross‐sectional study using the National Inpatient Sample (2018 to 2020), including adults
Ali Yazdanyar, Joshua Baker, Katherine D. Wysham, Mohammed Yousufuddin, Farah Acher Kaiksow, Michael M. Ward   +5 more
wiley   +1 more source

Arterial Spin Labeling Imaging of a Giant Aneurysm Leading to Subarachnoid Hemorrhage following Cerebral Infarction

Case Reports in Neurology, 2018
An 83-year-old Japanese man was admitted with dysarthria and right hemiparesis. He had had a large intracranial aneurysm on the left internal carotid artery 5 years before admission and had been followed up under conservative treatment.
Tatsuya Ueno, Tatsuya Sasaki, Masatoshi Iwamura, Tomoya Kon, Jin-ichi Nunomura, Hiroshi Midorikawa, Masahiko Tomiyama   +6 more
doaj   +1 more source