Results 31 to 40 of about 88,846 (343)
A 28-year-old native Romanian homeless man presented to emergency department with two episodes of hemoptysis (estimated 300 ml) in the previous three days. For about two months he had been suffering from a dry cough with concurrent right-sided chest pain, asthenia, weight loss and a slight fever.
Lombardi, MA+4 more
openaire +5 more sources
Randomized, open-label, phase 1/2a study to determine the maximum tolerated dose of intraventricular sustained release nimodipine for subarachnoid hemorrhage (NEWTON [Nimodipine Microparticles to Enhance Recovery While Reducing Toxicity After Subarachnoid Hemorrhage]) [PDF]
BACKGROUND AND PURPOSE—: We conducted a randomized, open-label, phase 1/2a, dose-escalation study of intraventricular sustained-release nimodipine (EG-1962) to determine safety, tolerability, pharmacokinetics, and clinical effects in aneurysmal ...
Aldrich, Francois+10 more
core +3 more sources
Erythropoietin in vasospasm. From bench to bedside?
Aneurysmal subarachnoid haemorrhage is one of the most deleterious acute neurological diseases. The cerebral ischemia secondary to arterial vasospasm occurring after aneurysmal subarachnoid haemorrhage is still responsible for the considerable morbidity ...
Leonardo Christiaan Welling+3 more
doaj +1 more source
TGFβ (transforming growth factor-β) blockade induces a human-like disease in a nondissecting mouse model of abdominal aortic aneurysm [PDF]
Objective-Current experimental models of abdominal aortic aneurysm (AAA) do not accurately reproduce the major features of human AAA. We hypothesized that blockade of TGF beta (transforming growth factor-beta) activity-a guardian of vascular integrity ...
Clément, Marc+12 more
core +2 more sources
Background The majority (80%) of spontaneous subarachnoid hemorrhage (SAH) cases are caused by cerebral aneurysm rupture. The reported case fatality rate of aneurysmal SAH is still as high as 25 to 50%.
Nadya Noor Ramadhania+2 more
doaj +1 more source
A 54-year-old man had sudden onset chest pain with radiation to back 4 years ago. Right-sided aortic arch, aberrant left subclavian artery, and type B dissection were noted. The symptoms resolved after conservative treatment. One month prior to …
Shu-Hsun Chu+2 more
openaire +3 more sources
Aneurysmal subarachnoid hemorrhage (SAH) has the highest morbidity and mortality rates of all types of stroke. Many aneurysmal SAH patients continue to suffer from significant neurological morbidity and mortality directly related to delayed cerebral ...
George Kwok Chu Wong, Wai Sang Poon
doaj +1 more source
Minimal long-term neurobehavioral impairments after endovascular perforation subarachnoid hemorrhage in mice [PDF]
Cognitive deficits are among the most severe and pervasive consequences of aneurysmal subarachnoid hemorrhage (SAH). A critical step in developing therapies targeting such outcomes is the characterization of experimentally-tractable pre-clinical models ...
Brody, David L+5 more
core +2 more sources
The Clinical Features, Risk Factors, and Outcome of Aneurysmal Lesions in Behcet’s Disease
Objective. To investigate the clinical features and potential risk factors of aneurysmal lesions in Behcet’s disease (BD). Methods. We retrospectively reviewed the clinical data of BD patients with aneurysmal lesions in our institute from 1997 to 2017 ...
Jiaxin Zhou+12 more
doaj +1 more source
Aneurysmal bone cyst is a type of benign bone pathology with expansile and osteolytic features whose etiology remains unclear. Graves’ disease is an autoimmune disease characterized by diffuse goiter and hyperthyroidism. Moyamoya disease is a progressive
Cai Gao-Rui+2 more
doaj +1 more source