Progression of Coronary Artery Disease (CAD) from Stable Angina (SA) Towards Myocardial Infarction (MI): Role of Oxidative Stress [PDF]
Introduction: There is now a consensus that atherosclerosis represents a state of heightened oxidative stress which is characterized by lipid and protein oxidation in the vascular wall.
Neha Uppal, Vibha Uppal, Pankaj Uppal
doaj +1 more source
Fractional flow reserve versus angiography in guiding management to optimize outcomes in non–ST-elevation myocardial infarction (FAMOUS-NSTEMI): rationale and design of a randomized controlled clinical trial [PDF]
<p>Background: In patients with acute non–ST-elevation myocardial infarction (NSTEMI), coronary arteriography is usually recommended; but visual interpretation of the angiogram is subjective.
Balachandran, Kanarath P.+10 more
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SELL and GUCY1A1 Gene Polymorphisms in Patients with Unstable Angina
Acute ischaemia is mostly caused by the rupture of an unstable atherosclerotic plaque in a coronary artery, resulting in platelet accumulation and thrombus formation, which closes the lumen of the coronary vessel.
Damian Malinowski+4 more
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Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk [PDF]
<p><b>Objective:</b> The goal of this study was to examine the association of the antiinflammatory interleukin-10 (IL-10) with risk of cardiovascular disease (CVD).</p> <p><b>Methods and Results:</b> In the ...
Craen, A.J.M. de+11 more
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Coronary CT Angiography and 5-Year Risk of Myocardial Infarction. [PDF]
BACKGROUND: Although coronary computed tomographic angiography (CTA) improves diagnostic certainty in the assessment of patients with stable chest pain, its effect on 5-year clinical outcomes is unknown.
Adamson, Philip D.+37 more
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BACKGROUND: Differentiating between unstable angina and myocardial infarction (MI) is clinically important as they require different treatments. High sensitivity C-reactive protein (hs-CRP) has recently been recognized as prognostic factor in acute ...
Reza Madadi+3 more
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RESISTANCE TO ACETYLSALICYLIC ACID AND PREVALENCE OF THROMBOSIS IN PATIENTS WITH STABLE ANGINA
Aim. To estimate the prevalence of atherothrombotic complications depending on platelet sensitivity to acetylsalicylic acids (ASA) in patients with stable angina.Material and methods.
N. F. Putchinyan+2 more
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Pathogen burden, inflammation, proliferation and apoptosis in human in-stent restenosis - Tissue characteristics compared to primary atherosclerosis [PDF]
Pathogenic events leading to in-stent restenosis (ISR) are still incompletely understood. Among others, inflammation, immune reactions, deregulated cell death and growth have been suggested. Therefore, atherectomy probes from 21 patients with symptomatic
Abdelmegui AE+24 more
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The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis [PDF]
Atherosclerosis is a chronic inflammatory disease that is mediated by both the innate and adaptive immune responses. T lymphocytes, that together with B cells are the cellular effectors of the adaptive immune system, are currently endowed with crucial ...
Antunes, RF, Dumitriu, IE, Kaski, JC
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AbstractThe pathophysiology of unstable angina has been better elucidated in the past five years and has led to more rational therapy. Coronary arteries in patients with unstable angina have atherosclerotic plaques which are often complex and are the site of platelet activation and fibrin deposition.
P. N. Yu, W. A. Wallace, J. F. Richeson
openaire +3 more sources