Results 41 to 50 of about 59,189 (229)

Prospective randomized controlled trial study of liver function tests in unstable angina risk prediction [PDF]

مجلة جامعة الانبار للعلوم الصرفة
Cardiovascular diseases continue to be the leading cause of morbidity and mortality in developed nations. Elevated levels of liver function have recently been implicated as possible risk factors for cardiovascular disease in the adult population.
Fatimah Mezaal, Sami Mishlish, Kutayba Dawood   +2 more
doaj   +1 more source

Reduced plasma adiponectin levels relative to oxidized low density lipoprotein and nitric oxide in coronary artery disease patients

Clinics, 2011
INTRODUCTION: Adiponectin is a circulating hormone that is produced exclusively by adipocytes and has antiinflammatory and anti-atherogenic properties. The hypothesis that there are differences in adiponectin levels between stable and unstable coronary ...
Gholam Basati, Morteza Pourfarzam, Ahmad Movahedian, Saed Ziaaldin Samsamshariat, Nizal Sarrafzadegan   +4 more
doaj   +1 more source

Marked variation in eligibility criteria across registrational trials for relapsed diffuse large B‐cell lymphoma limits applicability to clinical practice

British Journal of Haematology, EarlyView.
Summary Therapeutic options for relapsed or refractory diffuse large B‐cell lymphoma (rDLBCL) have expanded following accelerated approvals based largely on surrogate end‐points, yet confirmatory studies have not consistently reproduced these benefits across all agents, and outcomes for many patients remain poor.
Elizabeth Goodall, Jodie Palmer, Arina Martynchyk, Niamh Waters, Fiona Swain, Tran Binh Giang, Tamara Marconi, Jamie Brennan, Gareth P. Gregory, Chan Cheah, Colm Keane, Eliza A. Hawkes   +11 more
wiley   +1 more source

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes, Florian Buehning, Tobias Lerchner, Julia Vogel, Raluca I. Mincu, Matthias Totzeck, Tienush Rassaf, Lars Michel   +7 more
wiley   +1 more source

Which doctors are influenced by a patient's age? A multi-method study of angina treatment in general practice, cardiology and gerontology

, 2007
Background: Elderly patients with cardiovascular disease are relatively undertreated and undertested. Objectives: To investigate whether, and how, individual doctors are influenced by a patient?s age in their investigation and treatment of angina ...
Harries, C, Forrest, D, Harvey, N, Forrest, Damien, Harries, Clare, McClelland, A, McClelland, Alistair, McClelland, Alastair, Harvey, Nigel, Bowling, Ann, Harries, Claire, Bowling, A   +11 more
core   +1 more source

Expert considerations to guide the development and delivery of an exercise intervention in people with type 2 diabetes‐related foot ulcer disease

Diabetic Medicine, EarlyView.
Abstract Objective Engaging in exercise presents unique challenges for those with type 2 diabetes (T2D) and diabetes‐related foot ulcer disease (DFUD). This brief report describes the development of practical considerations aiming to support exercise in people with T2D and DFUD.
Vicki L. Johnson, Vicky Hall, Rachel Berrington, Julia Burdon, Sally Schreder, Matthew McCarthy, Chris Brough, Patrick J. Highton, Michelle Hadjiconstantinou, Frances L. Game, Lisa J. Keogh, Solomon Tesfaye, Jonathan Valabhji, John R. Petrie, Ketan K. Dhatariya, Tom Yates, Melanie J. Davies, Kamlesh Khunti   +17 more
wiley   +1 more source

Clinical characteristics and in‐hospital mortality among insulin pump users with acute coronary syndrome in the predominantly open‐loop era: A UK‐wide MINAP registry analysis

Diabetic Medicine, EarlyView.
Abstract Background We compared characteristics of adults with insulin‐treated diabetes using continuous subcutaneous insulin infusion (CSII) versus multiple daily insulin injections (MDI) during admission with acute coronary syndrome (ACS) and identified factors associated with in‐hospital mortality among CSII users.
Harshal Deshmukh, Moosa Shaikh, Emma G. Wilmot, Eric Kilpatrick, Sudipta Chattopadhyay, Thozhukat Sathyapalan, Joseph John   +6 more
wiley   +1 more source

Persistent and selective upregulation of renin–angiotensin system in circulating T lymphocytes in unstable angina [PDF]

, 2017
Introduction: Unstable angina is associated with an acute systemic inflammatory reaction and circulating T lymphocytes are activated. We investigated whether in unstable angina with marked immune system activation a selective upregulation of the ...
Maria Boddi, Poggesi, Loredana, Boddi, Maria, Mirella Coppo, Bandinelli, Manuela, Manuela Bandinelli, Chiostri, Marco, Marco Chiostri, Coppo, Mirella, Loredana Poggesi   +9 more
core   +1 more source

Survodutide for the Treatment of Obesity Disease in Japanese Participants: Rationale, Design and Baseline Characteristics of the Phase 3 SYNCHRONIZE‐JP Trial

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims There is an unmet need for effective pharmacotherapy for obesity disease management in Japan. Survodutide is a novel glucagon receptor/glucagon‐like peptide‐1 receptor (GLP‐1R) dual agonist with the potential to induce greater weight reductions than GLP‐1R mono‐agonists. We report the design and baseline participant characteristics of the
Koutaro Yokote, Toshimasa Yamauchi, Yasushi Fukushima, Yoji Takatsuka, Marie Kato, Shijia Yan, Takayoshi Inoue, Luiza Borowska, Martina Brueckmann, Wataru Ogawa, on behalf of the SYNCHRONIZE‐JP Trial Investigators   +10 more
wiley   +1 more source

Elevated Levels of Plasmin-α2 Antiplasmin Complexes in Unstable Angina

, 1999
SummaryThe evidence of elevated levels of several biochemical markers of prothrombotic state in patients with unstable angina suggests that thrombus formation and lysis play a pivotal role in acute coronary syndromes.
Josep Guindo, Jordi Fontcuberta, Antoni Bayés-Genís, Miquel Fiol, Jose Dominguez, Artur Oliver, Lina Badimon, Jose Mateo, Antoni Bayés de Luna, Joan Carles Souto   +9 more
core   +1 more source