Results 61 to 70 of about 51,139 (197)

Impact of CYP2C19 and CYP3A4 Inhibitor Use on Clopidogrel Clinical Effectiveness in CYP2C19 Genotyped Patients Undergoing Percutaneous Coronary Intervention

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 531-541, August 2026.
CYP2C19 and CYP3A4 contribute to clopidogrel bioactivation. CYP2C19 no‐function alleles diminish clopidogrel's antiplatelet effects and clinical effectiveness. Coadministration of either a CYP2C19 or a CYP3A4 inhibitor may also reduce clopidogrel's antiplatelet effects and lead to phenoconversion in patients without a CYP2C19 no‐function allele (normal/
Danwei Shao   +8 more
wiley   +1 more source

Relationship between high-sensitivity C-reactive protein serum levels and the severity of coronary artery stenosis in patients with coronary artery disease

open access: yesARYA Atherosclerosis, 2016
BACKGROUND: High-sensitivity C-reactive protein (hs-CRP) inflammatory biomarker is one of the best informative markers of prognosis of coronary artery disease (CAD) that has been studied.
Seyed Masoud Seyedian   +3 more
doaj  

UNSTABLE ANGINA

open access: yesThe Professional Medical Journal, 2010
Objective: To determine the direct treatment cost of unstable angina (UA) withlow molecular weight heparin (LMWH) in conservative management. Study design: Prospectivestudy. Settings: Government cardiovascular hospital and private tertiary care hospital, Karachi.Study period: One year.
Shazia Alam   +3 more
openaire   +2 more sources

The role of leuko‐glycemic index in predicting 30‐day mortality in diabetic and non‐diabetic patients with acute coronary syndrome

open access: yesHong Kong Journal of Emergency Medicine, Volume 33, Issue 4, August 2026.
Abstract Background The leuko‐glycemic index (LGI) has been suggested as a possible prognostic marker for Acute coronary syndrome (ACS) but, its predictive capacity for mortality, especially among individuals with diabetes, remains poorly understood.
Ahmet Öztürk   +6 more
wiley   +1 more source

THE INFLUENCE OF CELL AND PLASMA HEMOSTASIS AND BIOMARKER LEVELS ON CLINICAL OUTCOMES IN PATIENTS WITH UNSTABLE ANGINA AND RESISTANCE TO ANTIPLATELET AGENTS

open access: yesЕвразийский Кардиологический Журнал, 2016
SUMMARY Objective: to assess the impact of cell plasma hemostasis disorders and the level of biomarkers on clinical outcomes and to develop laboratory diagnostic criteria forecast recurrent coronary events in patients with unstable angina.
L. G. Gelis   +5 more
doaj   +1 more source

Association Between GRACE Score and Right Ventricular Function Assessed by 3D Echocardiography in Patients With Acute Inferior STEMI Undergoing Primary PCI: A Pilot Study

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Objective This pilot study aimed to explore the association between the GRACE score and right ventricular (RV) function, including ejection fraction, volumes, and stroke volume, assessed using three‐dimensional echocardiography in patients with acute inferior STEMI undergoing primary PCI.
Hedieh Alimi   +4 more
wiley   +1 more source

ANALYSIS OF PRE-HOSPITAL TREATMENT OF ACUTE CORONARY SYNDROME

open access: yesРациональная фармакотерапия в кардиологии, 2015
Aim. To evaluate the pre-hospital treatment of patients with acute coronary syndromes (acute myocardial infarction and unstable angina) in 2001 and 2006.Material and methods. Retrospective pre-hospital treatment survey was performed in 1114 patients with
O. V. Reshetko   +2 more
doaj   +1 more source

Paeonol as a Multi‐Target Therapy for Neurological Disorders: Mechanistic Insights Into Neuroprotection

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 8, August 2026.
Paeonol (PNL) exhibits neuroprotective effects by reducing oxidative stress, neuroinflammation, and apoptosis. It enhances antioxidant defenses (SOD and GSH), inhibits pro‐inflammatory pathways (NF‐κB and TLR4), and modulates apoptotic proteins (Bcl‐2 and Bax).
Md. Sakib Al Hasan   +9 more
wiley   +1 more source

Does a circadian variation occur in myocardial ischemia over 48 hours in patients with unstable angina?

open access: yesArquivos Brasileiros de Cardiologia, 2000
OBJECTIVE: To study the incidence of and variation in myocardial ischemia over 48 hours in patients with unstable angina. METHODS: Thirty-nine patients with unstable angina underwent long-term electrocardiography for 48 hours.
Luiz Antônio Machado César   +6 more
doaj   +1 more source

Hsa_circ_0044097 Serves as a Promising Biomarker of Atherosclerosis and Its Effects on Vascular Smooth Cell Proliferation and Migration

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Hsa_circ_0044097 expression level was decreased AS patients and in ox‐LDL‐HASMC. The expression level of hsa_circ_0044097 is negatively correlated with the levels of hs‐CRP and LDL‐C. Hsa_circ_0044097 can be a biomarker for the diagnosis and prediction of MACE.
Cencen Ren, Yungen Jiao
wiley   +1 more source

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