Results 11 to 20 of about 8,938 (224)

A Common Variant at the 3'untranslated Region of the CCL7 Gene (rs17735770) Is Associated With Decreased Susceptibility to Coronary Heart Disease

Frontiers in Cardiovascular Medicine, 2022
Monocytes participate in the development of atherosclerosis through the action of cytokines and other inflammatory mediators. Among them, CCR2 and its ligands, CCL2 and CCL7 play an important role, so the main objective of this work was to determine ...
José María Medina-Gil, Ana Pérez-García, Pedro Saavedra-Santana, Asunción Díaz-Carrasco, Efrén Martínez-Quintana, Fayna Rodríguez-González, Cristina M. Ramírez, Marta Riaño, Paloma Garay-Sánchez, Antonio Tugores   +9 more
doaj   +1 more source

Development of cryptotanshinone-loaded pellets for angina chronotherapy: In vitro/in vivo prediction and evaluation

Asian Journal of Pharmaceutical Sciences, 2018
The clinical manifestations of variant angina is unevenly distributed during the 24 h, thus the in vivo performance of drugs should be tailored according to the angina circadian rhythm.
Zhenghua Li, Shuangshuang Zhang, Hongxiang Yan, Jianping Liu   +3 more
doaj   +1 more source

Phenotypic characteristics of the p.Asn215Ser (p.N215S) GLA mutation in male and female patients with Fabry disease: A multicenter Fabry Registry study. [PDF]

, 2018
BackgroundThe p.Asn215Ser or p.N215S GLA variant has been associated with late-onset cardiac variant of Fabry disease.MethodsTo expand on the scarce phenotype data, we analyzed natural history data from 125 p.N215S patients (66 females, 59 males ...
Brand, Eva, Burlina, Alessandro, Cecchi, Franco, Garman, Scott C, Germain, Dominique P, Jovanovic, Ana, Kempf, Judy, Laney, Dawn A, Linhart, Aleš, Maródi, László, Nicholls, Kathy, Ortiz, Alberto, Pieruzzi, Federico, Shankar, Suma P, Waldek, Stephen, Wanner, Christoph   +15 more
core   +1 more source

Ventriculer fibrillation due to Prinzmetal angina in a pregnant patient

Türk Kardiyoloji Derneği Arşivi, 2015
Variant angina, which is also referred to as prinzmetal or coronary vasospastic angina, is a clinical entity characterized by episodes of angina pectoris, usually at rest and often between midnight and early morning, in association with ST-segment ...
Ahmet Gündeş, Ahmet Çelik, İsmail Türkay Özcan, Ahmet Çamsarı   +3 more
doaj   +1 more source

Morte súbita e angina vasoespástica [PDF]

, 2002
Variant angina is defined by chest pain occurring at rest associated with transitory ST segment elevation on ECG, and is caused by a spasm of a coronary artery.
Andrea G Maria, Cacilda Dias Pereira, Claudio M Costa-Neto, Elaine Medeiros Floriano, Fernando Luiz De Lucca, João B Pesquero, Miriam G Jasiulionis, Patricia Dillenburg-Pilla, Rosana I Reis, Simone Gusmão Ramos   +9 more
core   +4 more sources

Nifedipine in the treatment of unstable angina, coronary spasm and myocardial ischemia [PDF]

, 1981
The effects of nifedipine, a potent calcium antagonist, were studied in patients with unstable angina, coronary spasm and myocardial ischemia.
Brower, R.W. (Ronald), Hugenholtz, P.G. (Paul), Michels, H.R. (Herman), Serruys, P.W.J.C. (Patrick)   +3 more
core   +1 more source

The NLRP3 Genetic Variant (rs10754555) Reduces the Risk of Adverse Outcome in Middle-Aged Patients with Chronic Coronary Syndrome

Journal of Immunology Research, 2022
Background. Inflammation is central in development of cardiovascular disease (CVD). Aberrant function of the Nod-Like Receptor Protein 3 (NLRP3) inflammasome, a central mediator in the proinflammatory response, has been associated with atherosclerosis ...
Trine B. Opstad, Jostein Nordeng, Alf-Aage R. Pettersen, Sissel Åkra, Vibeke Bratseth, Hani Zaidi, Ragnhild Helseth, Svein Solheim, Ingebjørg Seljeflot   +8 more
doaj   +1 more source

The common-866G > A variant in the promoter of UCP2 is associated with decreased risk of coronary artery disease in type 2 diabetic men [PDF]

, 2008
OBJECTIVE-Uncoupling protein 2 (UCP2) is a physiological downregulator of reactive oxygen species generation and plays an antiatherogenic role in the vascular wall. A common variant in the UCP2 promoter (-866G>A) modulates mRNA expression, with increased
Bouche, Clara, Brenner, Guilherme M., Cheurfa, Nadir, Dubois-Laforgue, Daniele, Ferrarezi, Daniela A. F., Fumeron, Frederic, Le Feuvre, Claude, Marre, Michel, Reis, Andre F., Timsit, Jose, Velho, Gilberto   +10 more
core   +1 more source

Genetic Variation in ADAMTS13 is Related to VWF Levels, Atrial Fibrillation and Cerebral Ischemic Events

Clinical and Applied Thrombosis/Hemostasis, 2022
Introduction ADAMTS13 cleaves von Willebrand factor (VWF) multimers into less active fragments. Both markers have been related to cardiovascular disease (CVD).
Ellen M. K. Warlo MD, Vibeke Bratseth MSc, PhD, Alf-Åge R. Pettersen MD, PhD, Pål Andre Holme MD, PhD, Harald Arnesen MD, PhD, Ingebjørg Seljeflot PhD, Trine B. Opstad MSc, PhD   +6 more
doaj   +1 more source

Plasma proteome changes in cardiovascular disease patients: novel isoforms of apolipoprotein A1 [PDF]

, 2011
Background The aim of this proteomic study was to look for changes taking place in plasma proteomes of patients with acute myocardial infarction (AMI), unstable angina pectoris (UAP), and stable angina pectoris (SAP).
Pavel Májek, Zuzana Reicheltová, Jiří Suttnar, Martin Malý, Milan Oravec, Klára Pečánková, Jan E Dyr   +6 more
core   +1 more source