Results 41 to 50 of about 4,086 (172)

A 52‐Week Efficacy and Safety Study of Teneligliptin, as an Add‐On to Empagliflozin and Metformin in Patients With Type 2 Diabetes Mellitus: A Randomised, Double‐Blind, Placebo‐Controlled Phase 3 Trial (TERA305 Study)

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To evaluate the long‐term efficacy and safety of teneligliptin add‐on in patients with type 2 diabetes mellitus (T2DM) inadequately controlled with metformin and empagliflozin. Materials and Methods In this randomised, double‐blind, phase 3 trial, 214 patients received teneligliptin 20 mg (n = 107) or placebo (n = 107) once daily for 24 ...
Jun Sung Moon, Kyung Ah Han, Dong‐Lim Kim, Sang Yong Kim, Soo‐Kyung Kim, Bon Jeong Ku, Woo Je Lee, Tae Keun Oh, Ji A Seo, Sang‐Ah Chang, Moon‐Kyu Lee, Kyu Jeung Ahn, Chul Sik Kim, Tae Nyun Kim, Bong‐Soo Cha   +14 more
wiley   +1 more source

Perceived Confidence in Managing Medical Emergencies Among Dental Students: The Significance of Technical Knowledge and Emotional Intelligence

European Journal of Dental Education, EarlyView.
ABSTRACT Aim This study aimed to evaluate the technical, practical and emotional factors associated with the self‐reported confidence of dental students in managing medical emergencies and urgent situations. Materials and Methods A cross‐sectional study was conducted with 100 students enrolled in the clinical courses of a public dentistry programme in ...
Tecianny Nunes de Aquino, Taysllan Torquato Benevides, Maria Luísa de Assis Braga, Annyelle Anastácio Cordeiro, Ana Flávia Granville‐Garcia, Érick Tássio Barbosa Neves   +5 more
wiley   +1 more source

Online tool for refining socio‐economic analyses better than postcodes: the example of cardiovascular disease in type 2 diabetes in the FIELD trial

Internal Medicine Journal, EarlyView.
Abstract Background Socio‐economic status (SES) is strongly linked to health outcomes but remains difficult to measure accurately. Conventional approaches based on large geographical units (e.g. postcodes) may obscure SES effects evident at smaller scales.
Andrzej S. Januszewski, Liping Li, Rachel L. O'Connell, James D. Best, R. John Simes, David R. Sullivan, Timothy M. E. Davis, Anthony C. Keech, on behalf of FIELD Trial Investigators   +8 more
wiley   +1 more source

Long‐term effects of tofogliflozin on renal function in patients with type 2 diabetes: A retrospective multicenter study

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims To investigate the long‐term renal effects of tofogliflozin, with the shortest half‐life among sodium–glucose cotransporter 2 inhibitors, in real‐world clinical practice. Materials and methods We retrospectively enrolled patients with type 2 diabetes mellitus treated at three affiliated hospitals between January 2015 and May 2024.
Natsuko Shinagawa, Hiroshi Okada, Junya Hironaka, Shinta Yamamoto, Mari Yoneda, Sayaka Kawai, Yuto Saijyo, Tomoya Katayama, Hanako Nakajima, Akio Kishi, Noriyuki Kitagawa, Naoko Nakanishi, Masahide Hamaguchi, Michiaki Fukui   +13 more
wiley   +1 more source

Trial Protocol: A Randomised, Controlled Cross‐Over Trial Evaluating the Digital Sleep Revolution Diagnostic‐Therapeutic Pathway for Obstructive Sleep Apnoea

Journal of Sleep Research, EarlyView.
ABSTRACT Obstructive sleep apnoea (OSA) is common, but current diagnostic pathways rely on single‐night assessment and the apnoea–hypopnoea index. Both are limited for assessment of variability and linking only weakly to symptoms, comorbidity and treatment response.
Ludger Grote, Erna Sif Arnardottir, Özen K. Basoglu, Maria R. Bonsignore, Zoran Dogas, Marta Drummond, Francesco Fanfulla, Haralampos Gouveris, Carolina Lombardi, Stefan Mihaicuta, Athanasia Pataka, Thomas Penzel, Winfried Randerath, Silke Ryan, Tarja Saaresranta, Sophia Schiza, Pawel Sliwinski, Richard Staats, Dries Testelmans, Paschalis Steiropoulos, Georgia Trakada, Johan Verbraecken, Sebastien Bailly, Anna Sigridur Islind, Timo Leppänen, Dirk Pevernagie, Ding Zou, Dimitri Ferretti, Jan Hedner, the Sleep Revolution Collaborators   +29 more
wiley   +1 more source

Histological Helicobacter pylori Density Might Not be Associated With the Severity of Neutrophilic Inflammatory Activity

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Background While the Updated Sydney System classifies Helicobacter pylori density together with inflammatory scores, the clinical relevance of bacterial load remains uncertain. This study aimed to assess the association between histological H. pylori density and the severity of gastric inflammatory activity.
Guochun Lou, Zhengchen Yu, YongWei Wang, BingQiang Xu, Qin Du, Jun Ye   +5 more
wiley   +1 more source

Economic Burden of Overweight and Obesity in Sweden: Current Estimates and Future Projections

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 9871-9879, November 2026.
ABSTRACT Aims Overweight and obesity are major public health challenges and well‐established risk factors for cardiovascular disease, cancer and premature mortality. We estimated the economic burden of overweight and obesity in Sweden in 2023 and projected the future economic burden in 2040 under alternative scenarios of increasing prevalence ...
Adam Fridhammar, Jovanna Dahlgren, Marije Galavazi, Lena Hjelm, Jonatan Dereke, Katarina Steen Carlsson   +5 more
wiley   +1 more source

Luteolin-7-O-β-d-glucuronide Ameliorates Cerebral Ischemic Injury: Involvement of RIP3/MLKL Signaling Pathway

Molecules
Luteolin-7-O-β-d-glucuronide (LGU) is a major active flavonoid glycoside compound that is extracted from Ixeris sonchifolia (Bge.) Hance, and it is a Chinese medicinal herb mainly used for the treatment of coronary heart disease, angina pectoris ...
Xing Fan, Fang Lin, Yu Chen, Yuling Dou, Ting Li, Xinxin Jin, Jintao Song, Fang Wang   +7 more
doaj   +1 more source

Quality of Diabetes Care Among Older Adults in Germany—Results of the Study on Health of Older People 2022/2023 Compared With Previous National Health Surveys

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10018-10027, November 2026.
ABSTRACT Aims The study aims (1) to evaluate the quality of diabetes care considering guideline‐recommended medical therapies, cardiometabolic factors, and self‐management of health behaviours among older adults with diabetes in Germany, and (2) to examine time trends.
Yong Du, Giselle Sarganas, Beate Gaertner, Maike Buchmann, Judith Fuchs, Hannelore Neuhauser, Christin Heidemann   +6 more
wiley   +1 more source

Initiation of SGLT2 Inhibitors Versus DPP‐4 Inhibitors in Metformin Users and Risk of Incident Depression: A Nationwide, Claims‐Based Active‐Comparator New‐User Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10765-10779, November 2026.
ABSTRACT Aims To examine the association between initiation of sodium‐glucose cotransporter‐2 (SGLT2) inhibitors and risk of incident depression compared with dipeptidyl peptidase‐4 (DPP‐4) inhibitors among adults with newly diagnosed Type 2 diabetes receiving metformin.
Sangwoo Park, Seogsong Jeong, Hye Jun Kim, Dae Ho Lee, Soo Jung Choi, Sang Min Park   +5 more
wiley   +1 more source