Results 51 to 60 of about 4,086 (172)
Multitarget Drug Design for Cardiovascular Disease: Bridging Chemistry and Medicine
ChemMedChem, Volume 21, Issue 19, 14 October 2026.Many pathophysiological pathways associated with cardiovascular diseases involve multiple drug targets. This article reviews recent advances in the development of pharmacological compounds capable of simultaneously modulating multiple mechanisms. Multitarget drugs offer a promising therapeutic approach for complex cardiovascular disorders, including ...
Gyuzel Y. Mitronova +3 more
wiley +1 more source
The Risk of Cardiovascular Diseases for Shift Workers in the Prospective Heinz Nixdorf Recall Study
American Journal of Industrial Medicine, Volume 69, Issue 10, Page 845-856, October 2026.ABSTRACT Background Shift work can disrupt circadian rhythms and is postulated to play a role in cardiovascular diseases (CVD). In the German prospective population‐based Heinz Nixdorf Recall Study, we analyzed longitudinal associations between shift work and night‐shift work with CVD.
Katharina Wichert +7 more
wiley +1 more source
Cancer and Hypertension: Shared Mechanisms, Treatment Interactions, and Clinical Management
Cancer Medicine, Volume 15, Issue 10, October 2026.ABSTRACT Cancer and hypertension (HTN) frequently coexist, and their relationship is increasingly recognized as a clinically relevant intersection between oncology and cardiovascular medicine. However, the extent to which this association reflects shared risk factors, common biological mechanisms, or treatment‐related effects remains incompletely ...
Peizhi Jia +5 more
wiley +1 more source
Variant angina pectoris associated with FOLFOX4 therapy
World Journal of Gastrointestinal Oncology, 2011 The patient was a 71-year-old man who underwent a right hemicolectomy for ascending colon cancer (pT3, pN1, pM0) and who opted not to receive adjuvant chemotherapy. Eight months later, multiple liver metastases occurred. He therefore received FOLFOX4 (5-fluorouracil/leucovorin and 85 mg/m(2) oxaliplatin) therapy, up to a total of 5 courses, and showed ...
Hiromichi, Yamane +7 more
openaire +2 more sources
Clinical Cardiology, Volume 49, Issue 10, October 2026.Elevated hemoglobin glycation index is associated with higher cardiovascular disease prevalence in middle‐aged and older adults with hip fracture in CHARLS, independent of diabetes. Findings were attenuated in survey‐weighted NHANES. HGI may serve as a complementary marker of inter‐individual glycation variation.
Xinyu Ma, Bo Yuan
wiley +1 more source
Clinical Cardiology, Volume 49, Issue 10, October 2026.In Iran, age‐standardized ischemic heart disease mortality and incidence declined from 1990 to 2019, while absolute incident cases increased substantially. Burden remained higher in men and older adults, with marked provincial variation, highlighting the need for stronger prevention and more standardized national surveillance.
Mehrdad Rabiee Rad +12 more
wiley +1 more source
Postprandial Changes in Thoracic Aortic Flow Detected by 4D Flow MRI May Influence Study Results
Journal of Magnetic Resonance Imaging, Volume 64, Issue 4, Page 898-905, October 2026.ABSTRACT Background While there is a growing body of data using 4D flow MRI to distinguish between normal and abnormal blood flow values in the thoracic aorta, the extent of physiological variation or lack thereof is potentially undervalued. Physiological processes such as postprandial changes to hemodynamics might influence data, normal values, follow‐
Maren Friederike Balks +11 more
wiley +1 more source
Zdravniški Vestnik, 2004 Background. A variant form of angina pectoris (VAP) is caused by coronary vessel spasm and occures in patients with and without varying degrees of obstructive coronary artery disease.
Franci Cesar +2 more
doaj
Isosorbide dinitrate and nifedipine in variant angina pectoris
American Heart Journal, 1985 The efficacy of isosorbide dinitrate (ISDN) in variant angina is enhanced by the addition of a calcium antagonist. A prospective double-blind, crossover trial of ISDN, 40 to 120 mg/day, and nifedipine, 40 to 120 mg/day, in 19 patients with variant angina and various degrees of coronary atherosclerosis showed that although both agents were equally ...
Division of Cardiology, Department of Medicine, University of Florida College of Medicine Gainesville, Fla, USA. ( host institution ) +5 more
openaire +3 more sources
World Journal of Surgery, Volume 50, Issue 10, Page 2987-2995, October 2026.This study aimed to clarify the correlation between anastomotic leakage and anastomotic position after esophagectomy for esophageal cancer, stratified by gastric conduit blood flow assessed using indocyanine green (ICG) fluorescence imaging. ABSTRACT Background This study aimed to clarify the correlation between anastomotic leakage and anastomotic ...
Yamato Ninomiya +9 more
wiley +1 more source