Results 41 to 50 of about 561 (202)

Investigação de alterações no Exons 2 do gene ANGPT1 e 9 do gene PLG em pacientes com angioedema hereditário e C1-INH normal [PDF]

, 2019
Orientador: Prof. Dr. Nelson Rosário FilhoCoorientadora: Profa. Dra. Lilian Pereira FerrariDissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências da Saúde, Programa de Pós-Graduação em Medicina Interna.
Kruk, Tatielly
core  

Global, Regional, and National Burden of Urticaria (1990–2021) and Forecasts to 2036: Systematic Analysis of the Global Burden of Disease Study 2021

Medicine Advances, EarlyView.
In our study, we conducted a comprehensive and systematic analysis of the latest global disease burden of urticaria from an epidemiological perspective, employing multiple analytical approaches. Specifically, we examined the burden of urticaria in terms of incidence, prevalence, and disability‐adjusted life years, stratified by sex, age, and region, as
Xingke Zhu, Qing Lv
wiley   +1 more source

Hereditary angioedema: how to approach it at the emergency department?

Einstein (São Paulo)
Angioedema attacks are common causes of emergency care, and due to the potential for severity, it is important that professionals who work in these services know their causes and management.
Faradiba Sarquis Serpa, Eli Mansour, Marcelo Vivolo Aun, Pedro Giavina-Bianchi, Herberto José Chong Neto, Luisa Karla Arruda, Regis Albuquerque Campos, Antônio Abílio Motta, Eliana Toledo, Anete Sevciovic Grumach, Solange Oliveira Rodrigues Valle   +10 more
doaj   +2 more sources

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

Cross Sectional Study of Prenatal Diagnosis Uptake Among Individuals With Genetic Conditions

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Prenatal diagnostic genetic testing allows for early identification of significant fetal conditions and enables informed decision‐making regarding management options. The aim of this study was to assess prenatal testing practice among individuals with genetic conditions.
Ebunoluwa Ojo, Roni Zemet, Allyson Nevins, Katherine Abraham, April D. Adams   +4 more
wiley   +1 more source

Analysis of Sleep Quality in Patients with Hereditary Angioedema

ABCS Health Sciences
Introduction: Sleep plays a crucial role in human health, both physiologically and mentally, responsible for body repair and regeneration. This may be affected by patients with Hereditary Angioedema (HAE), a rare and serious genetic disease of the ...
Tatielly Kruk, Lucas Marques Fortunato, Caroline Guth de Freitas Batista de Moraes, Charles Francisco Ferreira, Laura Baccule Brandão, João Guilherme Fiorani Borgio, Herberto José Chong-Neto, Lilian Pereira Ferrari, Nelson Augusto Rosário Filho   +8 more
doaj   +1 more source

Clinical characteristics of immediate allergic adverse reactions to intravenous amoxicillin‒clavulanic acid in conscious dogs

Veterinary Record, EarlyView.
Abstract Background Amoxicillin‒clavulanic acid (AMC) is one of the most frequently used antibiotics in small animal practice, and reports on adverse reactions are scarce. The aim of this study was to describe the clinical characteristics of immediate allergic adverse reactions to intravenous (IV) AMC in conscious dogs. Methods The medical records of a
Leonel Frutuoso, Anna Threlfall
wiley   +1 more source

The hereditary angioedema syndromes [PDF]

Journal of Clinical Investigation, 2018
Hereditary angioedema (HAE) is a rare genetic disorder primarily caused by mutations in the SERPING1 gene encoding the C1 inhibitor (C1INH) that leads to plasma deficiency, resulting in recurrent attacks of severe swelling. In the current issue of the JCI, Haslund et al.
openaire   +2 more sources

Unmet needs in the management of hereditary angioedema from the perspective of Brazilian patients

World Allergy Organization Journal
Introduction: Hereditary angioedema (HAE) is a rare genetic disease characterized by recurrent, potentially life-threatening angioedema episodes. Despite its severity, including the risk of asphyxiation, HAE often remains underdiagnosed.
Pedro Giavina-Bianchi, MD, PhD, Mara Giavina-Bianchi, MD, PhD, Raquel de Oliveira Martins, Maria Cristina Fortunato, PharmD, Ana Claudia Guersoni, MD, PhD   +4 more
doaj   +1 more source

Medical Malpractice in the Management of Angioedema: A Multidisciplinary Westlaw Analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background The management of acute angioedema is challenging and involves providers in multiple specialties. Timing of evaluation and intervention is imperative and requires effective communication between these groups, as treatment delays and improper management can lead to airway compromise and death.
Emma De Ravin, Neel R. Sangal, Daniel Uralov, Karthik Rajasekaran   +3 more
wiley   +1 more source