Results 71 to 80 of about 616 (213)

Berotralstat and Health‐Related Quality of Life in Hereditary Angioedema: Pooled Analysis of the APeX‐2 and APeX‐J Trials

Clinical &Experimental Allergy, EarlyView.
Pooled analysis of the phase 3 APeX‐2 and APeX‐J trials evaluated the impact of berotralstat 150 mg on health‐related quality of life in patients with hereditary angioedema using the Angioedema Quality of Life (AE‐QoL) questionnaire. Berotralstat significantly improved AE‐QoL total and domain scores for daily functioning and fears/shame versus placebo ...
Teresa Caballero, Sorena Kiani‐Alikhan, Douglas T. Johnston, Aolin Wang, Lorena Lopez‐Gonzalez, Zheng‐Yi Zhou, Fan Yang, Hannah H. Kim, Sandra Nestler‐Parr, Dianne Tomita, Patrick Gillard, Tamar Kinaciyan   +11 more
wiley   +1 more source

Patch Test Results With the European Baseline Series, 2021/2022—Joint European Results of the ESSCAA and the EBSB Working Groups of the ESCD, and the GEIDACC

Contact Dermatitis, EarlyView.
ABSTRACT Background Patch test results obtained with the European Baseline Series (EBS) in its current version serve both contact allergy surveillance and (re‐)assessing the diagnostic value of EBS allergens. Objectives To present results of current EBS patch testing, obtained in 59 departments in 14 European countries during 2021 and 2022.
Wolfgang Uter, S. Mark Wilkinson, Olivier Aerts, Andrea Bauer, Leopoldo Borrego, Richard Brans, Timo Buhl, Heinrich Dickel, Aleksandra Dugonik, Francesca Larese Filon, Ana Giménez Arnau, Cataldo Patruno, Györgyi Pónyai, Stamatis Gregoriou, Steffen Schubert, Dagmar Simon, Luca Stingeni, Skaidra Valiukevičienė, Elke Weisshaar, Thomas Werfel, Margarida Gonçalo, Marie‐L. A. Schuttelaar, ESSCAA and EBSB ESCD Working Groups, and the GEIDACC, Birger Kränke, Alexander Navarini, Philip Spring, Ulrike Beiteke, Cecilia Dietrich, Sibylle Schliemann, Detlef Becker, Swen Malte John, Nicola Wagner, Dimitra Koumaki, Maddalena Napolitano, Anna Belloni Fortina, Francesca Larese Filon, Rosella Gallo, Thomas Rustemeyer, Radoslaw Spiewak, Maja Kalac Pandurovic, Tanja Kmecl, Mojca Simončič Godnič, Nada Kecelj, Philippa Cousen, Ella Dendooven, Juan Francisco Silvestre Salvador, José Manuel Carrascosa Carrillo, Mónica Munera Campos, Esther Serra Baldrich, Gemma Melé‐Ninot, Cristina Barrabés Torrella, David Pesqué, María Antonia Pastor Nieto, Francisco Navarro Triviño, Inmaculada Ruiz Gonzales, Enrique Gómez de la Fuente, Susana Córdoba Guijarro, Francisco Javier Ortiz de Frutos, Fátima Tous Romero, Tatiana Sanz Sánchez, Pablo Chicharro Manso, Marta Andreu Barasoain, Marta Elosua González, Araceli Sánchez Gilo, Paloma Sánchez‐Pedreño Guillén, Pedro Mercader‐García, Carmen Paredes Suárez, María Elena Gatica Ortega, José Juan Pereyra Rodríguez, Javier Miquel Miquel, Mercedes Rodríguez Serna, Violeta Zaragoza Ninet, Ricardo González Pérez   +73 more
wiley   +1 more source

Acquired angioedema. Case report [PDF]

, 2019
Introducción: el angioedema adquirido es una rara enfermedad. Se clasifica en hereditario y adquirido. Las causas son variadas, pueden ser secundarios a enfermedades autoinmunes, síndromes linfoproliferativos y otras neoplasias.
López Ruiz, Osmany, Oyarzábal Guerra, Augusto, Oyarzábal Guerra, Luis Felipe   +2 more
core   +1 more source

The Shared Genetic Architecture of Modifiable Risk for Dementia and its Influence on Brain Health [PDF]

, 2022
Targeting modifiable risk factors for dementia may prevent or delay dementia. However, the mechanisms by which risk factors influence dementia remain unclear and current research often ignores commonality between risk factors.
Foote, I
core  

Garadacimab for the long‐term prophylaxis of hereditary angioedema

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Hereditary angioedema (HAE), a rare and debilitating disease characterized by recurrent and spontaneous attacks of tissue swelling, has a high unmet therapeutic need, with many patients experiencing insufficient disease control with current prophylactic treatments.
Emel Aygören‐Pürsün, Regina Treudler, Petra Staubach, Inmaculada Martinez Saguer, Thomas Linhoff, Markus Magerl   +5 more
wiley   +1 more source

Virtual reality in specialized dentistry: employing virtual reality for the alleviation of pain and anxiety in hereditary angioedema patients. [PDF]

BACKGROUNDː Following an episode of hereditary angioedema (HAE), dental anxiety commonly arises, and many patients find it challenging to access proper care.
Arcuri C., Cardelli P., De Angelis R., Pujia A. M., Rosa A.   +4 more
core  

Hereditary Angioedema: Research Project: Clinic and Podiatric Attitude [PDF]

, 2018
[Resumen] El Angioedema Hereditario (AEH), es una enfermedad poco frecuente, pero de gran importancia para la calidad de vida de la persona que la padece, debido a la recurrencia de los síntomas y al riesgo vital en ciertas circunstancias.
Lois Antelo, María José
core  

Cricothyroidotomy in a angiotensin-converting enzyme (ACE) Inhibitor tongue´s angioedema. [PDF]

, 2013
[ES] El angioedema hereditario por Inhibidores de la enzima convertidora de angiotensina (IECA) es un trastorno muy infrecuente. Suele afectar a la mucosa de la vía aérea supeior y producir cuadros obstructivos de rápida evolución con necesidad de ...
Acle Cervera, Leticia, García Zornoza, Roberto, Morales Angulo, Carmelo, Rubio Suárez, Antonio   +3 more
core   +1 more source

Gene Editing for Haemophilia—The Next Frontier

Haemophilia, EarlyView.
ABSTRACT The recently approved haemophilia A and B gene therapies via adeno‐associated virus (AAV) showed a promising therapeutic response after a single injection, but there are still limitations, including the potential loss of transgene expression and restriction in adults.
Mirko Pinotti, Gregory A. Newby, Sundar Selvaraj, Steven W. Pipe   +3 more
wiley   +1 more source

Angioedema: a diagnostic dilemma [PDF]

, 2011
Introduction: Angioedema is a rare but potentially life threatening (fatal laryngeal edema) disease. It is a relapsing subcutaneous or submucosal edema caused by various factors.
Kaushik, Rachna, Pushpanshu, Kumar
core   +1 more source