Results 91 to 100 of about 251,433 (257)

A Triboelectric‐Hydrogel System for Mechano‐Metabolic Re‐Coupling in Skin Expansion: Recharging From Energy Crisis

Advanced Healthcare Materials, EarlyView.
Progressive skin expansion creates an energy crisis that compromises regenerative capacity. A self‐powered triboelectric‐hydrogel system (TP‐PAM/G) re‐couples mechanical loading with cellular metabolism by combining motion‐generated electrical stimulation and stress redistribution.
Xing Huang, Yuduo Zhu, Fei Liu, Lei Liu, Shengzhou Shan, Yujui Lai, Peiyi Li, Xiao Zhang, Xusong Luo, Mengling Chang, He Xu   +10 more
wiley   +1 more source

Correlation Between Treatment‐Related Adverse Events and Efficacy of Camrelizumab in Combination With Apatinib in Patients With Unresectable Hepatocellular Carcinoma

Cancer Medicine
Background The relationship between treatment‐related adverse events (TRAEs) and efficacy in patients receiving immune checkpoint inhibitors (ICIs) combined with anti‐angiogenic therapy remains unclear.
Ting Zhang, Sicheng Du, Ying Zhang, Rongrui Liu, Juan Li, Chuanhua Zhao, Jianming Xu   +6 more
doaj   +1 more source

Modeling Early Metastatic Progression in Breast Cancer Using a Barrier‐Free, Perfusable Spheroid‐on‐a‐Chip Platform

Advanced Healthcare Materials, EarlyView.
Open‐port, barrier‐free microfluidic device for modeling early metastatic progression. A centrally positioned tumor spheroid releases invasive cells that migrate through the surrounding matrix and intravasate into endothelialized lateral channels.
Vira Sharko, Claudia Olaizola‐Rodrigo, Clara Bayona, Teodora Ranđelović, Rosa Monge, Estela Solanas, Sara Oliván, Ignacio Ochoa   +7 more
wiley   +1 more source

Brain-Specific Angiogenesis Inhibitor 3 Is Expressed in the Cochlea and Is Necessary for Hearing Function in Mice. [PDF]

Int J Mol Sci, 2023
Saegusa C, Kakegawa W, Miura E, Aimi T, Mogi S, Harada T, Yamashita T, Yuzaki M, Fujioka M.   +8 more
europepmc   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source

Biocompatible Conjugated Electrospinning Nanofibrous Membrane With Self‐Powered Piezoelectric Capacity for Accelerated Wound Healing

Advanced Healthcare Materials, EarlyView.
A self‐powered PCL/gelatin‐PVDF‐TrFE/MXene conjugated electrospun membrane integrates biocompatibility with enhanced piezoelectric responsiveness. Mechanical deformation is converted into localized electrical signals that stimulate wound‐repair cells proliferation and migration, promote angiogenesis and tissue remodeling, and accelerate full‐thickness ...
Diandian Li, Ke Wu, Yangyang Lu, Qinglan Xia, Jialong Chen, Yifan Zhang, Zhaoyu Chen, Zhiyuan She, Junjin Jie, Juzi Xia, Muran Zhou, Aimei Zhong   +11 more
wiley   +1 more source

Charge‐Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti‐Cancer Treatment

Advanced Materials, EarlyView.
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol, Bochuan Hu, Eduard O. Bobylev, Martina Farber, Petrus C. M. Laan, Thomas J. F. Kock, Bauke Fontein, Johanna Erbani, Oscar Escalona‐Rayo, Seline S. Roose, Tom Keijer, Gabriel Forn‐Cuní, B. Ewa Snaar‐Jagalska, Leila Akkari, Joost N. H. Reek, Alexander Kros, Dennis Aschmann   +16 more
wiley   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Comparative In Vitro Studies of Materials Properties of Uncoated and Multifunctional/Biocompatible Ultrananocrystalline Diamond (UNCD) Coated‐Bioactive Bovine Nanohydroxyapatite Scaffolds for Transformational Bone Tissue Engineering

Advanced Materials Interfaces, EarlyView.
Research/technology development demonstrated physicochemical/mechanical properties of transformational integration of hydroxyapatite (HAp) scaffolds and HAp scaffolds coated with a unique breakthrough biocompatible ultrananocrystalline diamond (UNCD) coating produced by microwave plasma chemical vapor deposition (MPCVD) process.
Angelica M. Castillo‐Paz, Leon R. Bernal‐Alvarez, Dorian F. Cañon‐Davila, Lerma H. Chan‐Chan, Orlando Auciello, Rafael Ramírez‐Bon, Mario E. Rodriguez‐Garcia   +6 more
wiley   +1 more source

The Angiogenesis Inhibitor Isthmin-1 (ISM1) Is Overexpressed in Experimental Models of Glomerulopathy and Impairs the Viability of Podocytes. [PDF]

Int J Mol Sci, 2023
Sahiri V, Caron J, Roger E, Desterke C, Ghachem K, Mohamadou I, Serre J, Prakoura N, Fellahi S, Placier S, Adriouch S, Zhang L, Chadjichristos CE, Chatziantoniou C, Lorenzo HK, Boffa JJ.   +15 more
europepmc   +1 more source