Results 21 to 30 of about 251,433 (257)

Neoadjuvant chemotherapy with angiogenesis inhibitor in early-stage breast cancer: a systematic review and meta-analysis. [PDF]

Front Oncol
BackgroundBreast cancer, as a prevalent malignant tumor among women worldwide, has its malignant progression closely linked to angiogenesis mechanisms.
Wu J, Li H, Wei L, Yan X, Fang J, Peng L, Zhao X.   +6 more
europepmc   +2 more sources

Therapeutic Response of Soft Tissue Sarcoma With Novel SS18-POU5F1 Fusion: A Case Report

Frontiers in Oncology, 2021
A novel SS18-POU5F1 fusion gene was recently reported in soft tissue sarcoma occurring in three adolescent and young adult patients. Herein, we firstly reported the treatment response of SS18-POU5F1 sarcoma to immune checkpoint inhibitor, angiogenesis ...
Zengjun Liu, Zengjun Liu, Hongtu Yuan, Mingyong Han   +3 more
doaj   +1 more source

Comparative characteristics of the outcomes of the use of multidirectional intravitreal pharmacotherapy in the treatment of diabetic macular edema

Офтальмохирургия, 2021
Purpose. To conduct a comparative analysis of the effectiveness of intravitreal injection of dexamethasone-containing implant and aflibercept in macular edema in patients with diabetes mellitus.Material and methods.
M. M. Bikbov, K. I. Kudoyarova, R. M. Zainullin, T. R. Gilmanshin   +3 more
doaj   +1 more source

Thalidomide is an inhibitor of angiogenesis. [PDF]

Proceedings of the National Academy of Sciences, 1994
Thalidomide is a potent teratogen causing dysmelia (stunted limb growth) in humans. We have demonstrated that orally administered thalidomide is an inhibitor of angiogenesis induced by basic fibroblast growth factor in a rabbit cornea micropocket assay.
R J, D'Amato, M S, Loughnan, E, Flynn, J, Folkman   +3 more
openaire   +2 more sources

LncRNA LINC01857 reduces metastasis and angiogenesis in breast cancer cells via regulating miR-2052/CENPQ axis

Open Medicine, 2022
Long non-coding RNAs have been confirmed closely related to the metastasis and angiogenesis of breast cancer (BC). LINC01857 can promote the growth and metastasis of BC cells.
Qian Weiwei, Yang Linlin, Ni Yi, Yin Fei, Qin Lili, Yang Yang   +5 more
doaj   +1 more source

Angiogenesis Inhibitors as Anti-Cancer Therapy Following Renal Transplantation: A Case Report and Review of the Literature

Current Oncology, 2021
Solid organ transplant recipients on long-term immunosuppressive medication are at increased risk of developing malignancy, and treatment of advanced cancers with angiogenesis inhibitors in this context has not been widely studied.
Lawrence Kasherman, Jeffrey Doi, Katherine Karakasis, Jeffrey Schiff, Abhijat Kitchlu, Stephanie Lheureux, Amit M. Oza   +6 more
doaj   +1 more source

Efficacy and safety of angiogenesis inhibitors in advanced gastric cancer: a systematic review and meta-analysis

Journal of Hematology & Oncology, 2016
Monoclonal antibodies and small molecule tyrosine kinase inhibitors (TKIs) directed against the vascular endothelial growth factor (VEGF) or its receptors have been investigated in several studies for the treatment of advanced gastric cancer (GC). In the
Jing Yu, Yue Zhang, Lai-Han Leung, Lian Liu, Fan Yang, Xiaojun Yao   +5 more
doaj   +1 more source

Major Adverse Cardiovascular Events in Angiogenesis Inhibitor-Based Cancer Therapy: A Systematic Review and Meta-Analysis. [PDF]

J Am Heart Assoc
Background Angiogenesis inhibitors (AIs) are effective in cancer therapy due to their ability to suppress tumor vasculature. However, these agents are associated with significant cardiovascular toxicities, including hypertension, thrombosis, and heart ...
Tao Y, Cui W, Song W, Xu H, Zeng J, Li H.   +5 more
europepmc   +2 more sources

Angiogenesis Inhibitors in NSCLC [PDF]

International Journal of Molecular Sciences, 2017
Angiogenesis is a complex biological process that plays a relevant role in sustaining the microenvironment, growth, and metastatic potential of several tumors, including non-small cell lung cancer (NSCLC). Bevacizumab was the first angiogenesis inhibitor approved for the treatment of patients with advanced NSCLC in combination with chemotherapy ...
Manzo, Anna, Montanino, Agnese, Carillio, Guido, Costanzo, Raffaele, Sandomenico, Claudia, Normanno, Nicola, Piccirillo, Maria Carmela, Daniele, Gennaro, Perrone, Francesco, Rocco, Gaetano, Morabito, Alessandro   +10 more
openaire   +2 more sources

VEGF sticky‐trap: the first report of a non‐systemically acting angiogenesis inhibitor

EMBO Molecular Medicine, 2014
Current therapeutic anti‐angiogenic biologics used for the treatment of pathological ocular angiogenesis such as in diabetic retinopathy and wet macular degeneration often lead to detrimental side effects due to their interference with normal blood ...
David M Favara, Adrian L Harris
doaj   +1 more source