Results 31 to 40 of about 251,433 (257)

Delayed Healing of Tooth Extraction Sockets with Ramucirumab Use

Case Reports in Dentistry, 2020
Objective. An angiogenesis inhibitor can cause medication-related osteonecrosis of the jaw (MRONJ). To our knowledge, there has been no report that an angiogenesis inhibitor causes delayed healing of tooth extraction socket.
Yosuke Iijima, Miki Yamada, Shunsuke Hino, Motohiko Sano, Takahiro Kaneko, Norio Horie   +5 more
doaj   +1 more source

Inhibition of Pathological Retinal Neovascularization by a Small Peptide Derived from Human Tissue-Type Plasminogen Kringle 2

Frontiers in Pharmacology, 2020
Retinal neovascularization is a hallmark pathological process of numerous ocular diseases which comprise the most common causes of blindness and affect millions of people from infants to the elderly.
Qian Sun, Qian Sun, Qian Sun, Yinchen Shen, Yinchen Shen, Yinchen Shen, Li Su, Li Su, Li Su, Xun Xu, Xun Xu, Xun Xu   +11 more
doaj   +1 more source

Angiogenesis and angiogenesis inhibitors in paediatric diseases

European Journal of Pediatrics, 1992
Angiogenesis, the generation of new capillaries from existing blood vessels, is rarely observed in the healthy organism, but can present during various paediatric diseases. In this review, we describe recent progress in the understanding of pathological angiogenesis and approaches for an improved therapy of angiogenic childhood diseases.
Schweigerer, L., Fotsis, T.
openaire   +3 more sources

Angelica Dahurica ethanolic extract improves impaired wound healing by activating angiogenesis in diabetes. [PDF]

PLoS ONE, 2017
Abnormal angiogenesis plays an important role in impaired wound healing and development of chronic wounds in diabetes mellitus. Angelica dahurica radix is a common traditional Chinese medicine with wide spectrum medicinal effects.
Xiao-Na Zhang, Ze-Jun Ma, Ying Wang, Bei Sun, Xin Guo, Cong-Qing Pan, Li-Ming Chen   +6 more
doaj   +1 more source

Marine Cyanobacteria as Sources of Lead Anticancer Compounds: A Review of Families of Metabolites with Cytotoxic, Antiproliferative, and Antineoplastic Effects

Molecules, 2022
The marine environment is highly diverse, each living creature fighting to establish and proliferate. Among marine organisms, cyanobacteria are astounding secondary metabolite producers representing a wonderful source of biologically active molecules ...
Benjamín Robles-Bañuelos, Lorena María Durán-Riveroll, Edgar Rangel-López, Hugo Isidro Pérez-López, Leticia González-Maya   +4 more
doaj   +1 more source

Combination Therapy in Cancer: Doxorubicin in Combination with an N-terminal Peptide of Endostatin Suppresses Angiogenesis and Stimulates Apoptosis in the Breast Cancer [PDF]

International Journal of Molecular and Cellular Medicine, 2023
The combination of chemotherapy drugs with angiogenesis inhibitors improves response and survival and reduces the cytotoxic side effects and drug resistance in patients compared to chemotherapy alone. Here, we investigated the efficacy of the concomitant
Narges Sarabi, Reyhane Chamani, Elham Assareh, Omid Saberi, S. Mohsen Asghari   +4 more
doaj  

A case of retinal tear associated with use of sorafenib

Frontiers in Oncology, 2014
Inhibition of angiogenesis is a target in the treatment of a variety of malignancies. Sorafenib is an oral inhibitor of multiple tyrosine kinases involved in tumor angiogenesis.
Kelly M. Gaertner, Stephen H. Caldwell, Osama eRahma   +2 more
doaj   +1 more source

A MetAP2 inhibitor blocks adipogenesis, yet improves glucose uptake in cells

Adipocyte, 2019
Adipose tissue expansion involves angiogenesis to remodel its capillary network. The enzymemethionine aminopeptidase 2(MetAP2) promotes angiogenesis.MetAP2 inhibitors suppress angiogenesis and have potential anti-obesity effect.
Md Abu Bakkar Siddik, Bhaskar C. Das, Louis Weiss, Nikhil V. Dhurandhar, Vijay Hegde   +4 more
doaj   +1 more source

Discovery of a highly selective VEGFR2 kinase inhibitor CHMFL-VEGFR2-002 as a novel anti-angiogenesis agent

Acta Pharmaceutica Sinica B, 2020
Angiogenesis is an essential process in tumor growth, invasion and metastasis. VEGF receptor 2 (VEGFR2) inhibitors targeting tumor angiogenic pathway have been widely used in the clinical cancer treatment.
Zongru Jiang, Li Wang, Xuesong Liu, Cheng Chen, Beilei Wang, Wenliang Wang, Chen Hu, Kailin Yu, Ziping Qi, Qingwang Liu, Aoli Wang, Jing Liu, Guangchen Hong, Wenchao Wang, Qingsong Liu   +14 more
doaj   +1 more source

Host angiogenic reprogramming by Echinococcus multilocularis protoscoleces protein via PDGFR/PI3K/AKT cascade

Frontiers in Microbiology
BackgroundAlveolar echinococcosis (AE) is a globally present zoonotic disease caused by Echinococcus multilocularis (E. multilocularis) infection, characterized by the formation of tumor-like growths primarily in the liver, with the potential to spread ...
Xiaojuan Bi, Ning Yang, Ying Ke, Junlong Xue, Xue Zhang, Hui Liu, Jin Chu, Liang Li, Yingmei Shao, Guodong Lü, Tuerganaili Aji, Renyong Lin   +11 more
doaj   +1 more source