Results 1 to 10 of about 55,141 (338)

Conjunctival lymphangiectasia and retinal angiopathy in hereditary transthyretin amyloidosis [PDF]

open access: goldInternational Journal of Retina and Vitreous, 2022
Background Hereditary transthyretin amyloidosis (ATTR amyloidosis) is a rare condition where a mutation in the transthyretin gene leads to systemic deposition of amyloid.
Nikhil S. Patil   +2 more
doaj   +2 more sources

APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function

open access: yesScience Translational Medicine, 2021
Targeting APOE using an anti-APOE antibody ameliorates amyloid pathology while protecting cerebrovascular integrity and function. Controlling amyloid in brain and vasculature The genetic variant ε4 of the gene APOE (APOE4) is associated with increased ...
Monica Xiong   +2 more
exaly   +2 more sources

Convexity subarachnoid haemorrhage has a high risk of intracerebral haemorrhage in suspected cerebral amyloid angiopathy [PDF]

open access: hybrid, 2017
The risk of future symptomatic intracerebral haemorrhage (sICH) remains uncertain in patients with acute convexity subarachnoid haemorrhage (cSAH) associated with suspected cerebral amyloid angiopathy (CAA).
Ambler, G   +5 more
core   +3 more sources

Chronic Stress Exacerbates Cerebral Amyloid Angiopathy Through Promoting Neutrophil Extracellular Traps Formation

open access: yesAdvanced Science
Cerebral amyloid angiopathy (CAA) is the leading cause of vascular dementia among the elderly. Neuropsychiatric symptoms are commonly manifested in cerebral amyloid angiopathy patients but are usually considered as consequences of cerebral amyloid ...
Huipeng Huang   +11 more
doaj   +2 more sources

Understanding the Pathophysiology of Cerebral Amyloid Angiopathy [PDF]

open access: goldInternational Journal of Molecular Sciences, 2020
Cerebral amyloid angiopathy (CAA), one of the main types of cerebral small vessel disease, is a major cause of spontaneous intracerebral haemorrhage and an important contributor to cognitive decline in elderly patients. Despite the number of experimental
L. Gatti   +10 more
semanticscholar   +2 more sources

Cerebral Amyloid Angiopathy

open access: yesS.S. Korsakov Journal of Neurology and Psychiatry
Cerebral amyloid angiopathy (CAA) is a progressive disease characterized by the deposition of β-amyloid in the walls of blood vessels in the brain, which leads to their damage and disruption of normal blood flow. Morphologically, CAA is characterized by both isolated lesions (microhemorrhages with the appearance of cortical superficial siderosis ...
Singh J, Hegazy MI.
europepmc   +5 more sources

Cerebral amyloid angiopathy and Alzheimer disease — one peptide, two pathways

open access: yesNature Reviews Neurology, 2019
Steven M Greenberg   +2 more
exaly   +2 more sources

Efficacy and Safety of Berberine Alone for Several Metabolic Disorders: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

open access: yesFrontiers in Pharmacology, 2021
Background: Metabolic activity is the basic life activity of organisms and the fundamental for maintaining body functions. With the improvement of living standards, the incidence of metabolic disorder is also increasing.
Yu Ye   +7 more
doaj   +1 more source

Retinal amyloid angiopathy [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 2022
A 57-year-old male with previous myocardiopathy, polyneuropathy, bilateral cataract, and autonomic dysfunction had a family history of Familial Amyloid Polyneuropathy (FAP),. When he was 55 years old, he underwent a genetic testing, which detected a deleterious heterozygous mutation c.325G>A, Glu109Lys, on exon 3 of the Transthyretin gene, for the ...
Alex Tiburtino Meira   +3 more
openaire   +3 more sources

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