The Role of Basement Membranes in Cerebral Amyloid Angiopathy
Frontiers in Physiology, 2020 Dementia is a neuropsychiatric syndrome characterized by cognitive decline in multiple domains, often leading to functional impairment in activities of daily living, disability, and death.
M. Howe, L. McCullough, A. Urayama
semanticscholar +1 more source
Parkinson's Disease and Salivary Issues: A Survey
Gerodontology, EarlyView.ABSTRACT Background Salivary dysfunction, including xerostomia and drooling, is common in Parkinson's disease and further impairs oral health and quality of life, which are already compromised in this population. Their effective management demands deeper insight into the complexity of salivary dysfunction.
Beau D. M. van Dijk +3 more
wiley +1 more source
Applying the Canadian Head CT Criteria to Older Adults Seen in the Emergency Department After a Fall
Journal of the American Geriatrics Society, EarlyView.Prevalence of intracranial bleeding in adults based on the CCTHR criteria. ABSTRACT Background The Canadian CT Head Rule (CCTHR) is validated in adults who hit their head and experience loss of consciousness, amnesia, or disorientation. There is less evidence to guide brain imaging when the fall history is unclear.
Geoff Kerr +22 more
wiley +1 more source
The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy. [PDF]
, 2015 Chronic traumatic encephalopathy (CTE) is a neurodegeneration characterized by the abnormal accumulation of hyperphosphorylated tau protein within the brain. Like many other neurodegenerative conditions, at present, CTE can only be definitively diagnosed
Alvarez, Victor E +16 more
core +3 more sources
Identifying diagnostic and prognostic factors in cerebral amyloid angiopathy‐related inflammation: A systematic analysis of published and seven new cases [PDF]
, 2023 Levente Szalárdy +11 more
openalex +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker +2 more
wiley +1 more source
Early onset cerebral amyloid angiopathy following childhood exposure to cadaveric dura
Annals of Neurology, 2019 Amyloid‐β transmission has been described in patients both with and without iatrogenic Creutzfeldt–Jakob disease; however, there is little information regarding the clinical impact of this acquired amyloid‐β pathology during life.
G. Banerjee +10 more
semanticscholar +1 more source
Evaluation of Copper Chelation Therapy in a Transgenic Rat Model of Cerebral Amyloid Angiopathy
, 2023 Ashwin Ambi +6 more
openalex +2 more sources
Amyloid β alters vascular CaV1.2 channel spatiotemporal properties
The Journal of Physiology, EarlyView.Abstract figure legend Amyloid‐β1‐42 (Aβ1‐42) triggers a male‐specific signalling cascade influencing CaV1.2 spatiotemporal properties in cerebral vascular smooth muscle. The signalling pathway involves NADPH oxidase (NOX)‐derived reactive oxygen species (ROS) activation of protein kinase C (PKC). Aβ1‐42 can also activate protein kinase A (PKA).
Jade L. Taylor +5 more
wiley +1 more source