Results 131 to 140 of about 42,626 (296)

Parkinson's Disease: The Epidemiology, Risk Factors, Molecular Pathogenesis, Prevention, and Therapy

open access: yesMedComm, Volume 6, Issue 12, December 2025.
This graphical abstract summarizes the major components of this review on Parkinson's disease, including epidemiological trends, risk factor classification, peripheral and molecular pathogenesis, and both preventive and therapeutic strategies. The framework reflects the multidimensional organization of the text, covering disease burden, mechanistic ...
Xue‐Yao Guo   +5 more
wiley   +1 more source

The comparison of hearing loss among diabetic and non-diabetic patients [PDF]

open access: yes, 2011
Introduction: The prevalence of Diabetes Mellitus is steadily increasing. This is a multi- systemic abnormality, causing side- effects which are mainly irreversible.
Mansourian Azad, R., Taziki Mohammad, H.
core  

Target analysis and identification of curcumin against vascular calcification

open access: yesScientific Reports
To investigate the mechanism of curcumin (CUR) on vascular calcification (VC), we screen for common targets of CUR and atherosclerosis and verify the targets genes in vivo and in vitro experiments.
Qingjie Li   +8 more
doaj   +1 more source

Advances in molecular regulation and function of LDLR family in viral infection

open access: yesFrontiers in Microbiology
The low-density lipoprotein receptor (LDLR) family represents a crucial interface between cellular cholesterol homeostasis and viral pathogenesis. This review systematically examines the dual roles of these receptors in viral infections, encompassing ...
Qing Yao   +6 more
doaj   +1 more source

Systematized delusions in a patient with covert hepatic encephalopathy: A clinicopathological insight into prodromal dementia with Lewy bodies

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 4, Issue 4, December 2025.
Abstract Background Late‐onset psychosis is an early clinical manifestation of psychiatric‐onset prodromal dementia with Lewy bodies (DLB); however, its underlying neuropathology remains poorly understood. Clinicopathological correlations are often limited by the gap between symptom onset and the autopsy.
Hiroshige Fujishiro   +6 more
wiley   +1 more source

Superficial siderosis: a potential diagnostic marker of cerebral amyloid angiopathy in Alzheimer disease [PDF]

open access: yes, 2008
BACKGROUND AND PURPOSE: Superficial siderosis of the central nervous system results from chronic bleeding in the superficial layers of the cortex and spinal cord.
Feldman, H.   +5 more
core  

Monoclonal Antibody Therapies in Alzheimer's Disease: A Guide for Emergency Physicians

open access: yesEmergency Medicine Australasia, Volume 37, Issue 6, December 2025.
ABSTRACT Whilst the advent of novel disease‐modifying medications for Alzheimer's disease represents potential benefit for patients and caregivers, they may be associated with adverse events that present important considerations for emergency and primary care. This article seeks to highlight some of the challenges Emergency Departments may encounter in
Scott Wrigley   +7 more
wiley   +1 more source

Endoplasmic Reticulum Stress: A Novel Target for the Prevention and Treatment of Hypertension and Its Related Diseases

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 23, December 2025.
ABSTRACT Endoplasmic reticulum stress (ERS) emerges as a critical pathophysiological nexus in hypertension and related cardiovascular diseases. Chronic ERS activation via the IRE1α‐XBP1, ATF6, and PERK pathways drives vascular endothelial dysfunction (reduced NO bioavailability, increased ET‐1), renin‐angiotensin system (RAS) hyperactivation ...
Xin Ma   +6 more
wiley   +1 more source

A Holistic Nursing Programme Based on 24 h Holter Monitoring for Coronary Angiography Patients in the Perioperative Period

open access: yesJournal of Evaluation in Clinical Practice, Volume 31, Issue 8, December 2025.
ABSTRACT Aim This study developed, implemented, and evaluated the effectiveness of a holistic nursing program based on 24 h Holter monitoring for patients undergoing coronary angiography, aiming to improve nursing quality and reduce the incidence of coronary complications during the perioperative period.
Ting Liu, ShuangJiao Xu, Pingping Wang
wiley   +1 more source

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